Muhammad Wirawan Harahap
Universitas Muslim Indonesia

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Risk factors influencing caesarean wound infection (CWI) Yolanda Salsabila Dwi Putri; Reeny Purnamasari Juhamran; Ronaldo August Rambulangi; Nasrudin Andi Mappaware; Muhammad Wirawan Harahap
Malahayati International Journal of Nursing and Health Science Vol. 8 No. 9 (2025): Volume 8 Number 9
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v8i9.1342

Abstract

Background: Cesarean section (CS) is a delivery method that continues to increase and carries a risk of complications, one of which is surgical wound infection (SWI). SWI can hinder healing and increase morbidity. Risk factors for infection include preoperative, intraoperative, and postoperative conditions, necessitating analysis to prevent postoperative complications. Purpose: To identify risk factors for surgical site infection in Cesarean section procedures and to determine the association between nutritional status, hemoglobin levels, and wound care with the occurrence of surgical site infection. Method: This study is an observational analytical study using a cross-sectional approach conducted at RSIA Sitti Khadijah 1 Muhammadiyah Makassar from March to June 2025. Data were analyzed using univariate and bivariate analysis with the Chi-square test at a significance level of p < 0.05. Results: There was a significant association between several risk factors and the occurrence of postoperative wound infections following Cesarean section. Based on bivariate analysis, nutritional status, hemoglobin (Hb) levels, wound care, and type of cesarean section procedure were found to influence the occurrence of postoperative wound infections. However, although the duration of surgery showed a statistical association, the data obtained were not varied, so a definitive conclusion regarding the relationship between surgery duration and postoperative wound infections after cesarean section could not be drawn. Conclusion: Nutritional status, hemoglobin levels, wound care, and type of cesarean section are factors associated with the occurrence of postoperative wound infections after cesarean section. These findings highlight the importance of attention to maternal nutritional status, hemoglobin levels, wound care standards, and the selection of Cesarean section type in efforts to prevent postoperative infections. A comprehensive evaluation of these factors is necessary to minimize the risk of complications and improve patient safety.
Potential of Soursop Leaf Extract (Annona Muricata L.) as an Antimicrobial Against Staphylococcus epidermidis Aqil Fauziy; Nurelly N. Waspodo; Andi Alamanda Irwan; Yani Sodiqah; Dhian Karina; Muhammad Wirawan Harahap
International Journal of Health Science and Technology Vol. 7 No. 1 (2025): July
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v7i1.3966

Abstract

Staphylococcus epidermidis is an opportunistic bacterium that can cause infections, particularly in individuals with weakened immune systems. The increasing resistance to antibiotics has encouraged the use of medicinal plants such as soursop leaves (Annona muricata L.), which contain antibacterial compounds. This study aims to evaluate the antibacterial effectiveness of soursop leaf extract against the growth of Staphylococcus epidermidis at concentrations of 50%, 75%, and 100%. The study specifically investigated the inhibition zones formed at each concentration (50%, 75%, and 100%) of Annona muricata L. extract against Staphylococcus epidermidis, and compared the antibacterial activity across these three concentrations. This research used a laboratory experimental design with the Kirby-Bauer disc diffusion method to assess the antibacterial activity. The extract was prepared using 96% ethanol and tested at the concentrations stated. Gentamicin 10 μg was used as a positive control, while sterile distilled water served as the negative control. The inhibition zones were observed after 24 hours of incubation at 37°C. The results showed that soursop leaf extract at 50% and 75% concentrations produced inhibition zones categorized as resistant. At 100% concentration, the inhibition zone ranges from resistant to intermediate. The comparison across all three concentrations indicates that the 100% concentration demonstrated notable antimicrobial activity against Staphylococcus epidermidis.