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Nutritional, Hypoglycemic, and Haematinic Potentiality of Edible Mushroom Pleurotus tuber-regium (Rumph. ex Fr.) Singer Dandapat, Sukumar; Kumar, Manoj; Ranjan, Rakesh; Sinha, Manoranjan Prasad
Journal of Tropical Life Science Vol 9, No 2 (2019)
Publisher : Journal of Tropical Life Science

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Mycochemical composition, calorific value, the antioxidant activity of Pleurotus tuber- regium was analyzed and impact of P. tuber- regium extract on rat model especially glycemic, vitamins and blood parameters were explored to validate its medicinal importance. Mycochemical screening showed the presence of biochemicals such as phenols, flavonoids, proteins, carbohydrates etc. The extract showed good antioxidant activity (33.62% total antioxidant activity equivalent to 21.30 Âµg ascorbic acid). The extract showed dose -dependent hypoglycaemic activity by significant decreased average blood glucose level at high dose (100.62 Â± 1.04mg/dL) compare to control (124.40 Â± 1.45 mg/dL), haematinic activity by elevation of hemoglobin (14.75 Â± 0.24 g/dL) at a high dose of extract compared to control (11.66 Â± 0.21 g/dL). P. tuber-regium extract elevated vitamin B12 of rats at high dose of extract (449.60 Â± 3.12 pg/mL) compared to control (420.00 Â± 2.86pg/mL). P. tuber-regium extract showed a positive response to hypoglycemic, haematinic, and vitamin level of the body and posses high calorific value. Hence P. tuber-regium can be used as good fodder, medicinal and nutritional supplement.

Cutaneous Horn on the Right Supraclavicular Region in an Adolescent Female, a Rare Case Report Gupta, Rohit; Kumar, Manoj; Sinha, Ruchi; Sahu, Reva Shankar
The New Ropanasuri Journal of Surgery
Publisher : UI Scholars Hub

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Cutaneous horn (CH) is an outgrowth from the skin surface, composed of keratin, and associated with benign to malignant skin lesions. We report a case of CH in a 15-year-old female associated with Keratoacanthoma. It is uncommon in young people and is associated with a good prognosis because of its benign nature. This case needs to be reported as it highlights the rare occurrence of this condition in the younger age group and its good prognosis. Surgical excision is the treatment of choice, with histopathologic diagnosis playing a critical role in determining the nature and further treatment of this condition if required.

Physical and Numerical Modelling of Rockwool Insulated Landfill Liner Materials as a Heat Mitigation Method Widjaja, Emmanuella Stephanie; Ahmad, Afnan; Kumar, Manoj; Anggraini, Vivi
Indonesian Geotechnical Journal Vol. 3 No. 3 (2024): Vol. 3, No. 3, December 2024
Publisher : Himpunan Ahli Teknik Tanah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56144/igj.v3i3.106

The growing global amount of waste emphasizes the urgency of effective landfill management. The large amount of organic matter in landfill liners undergoes rapid biodegradation, generating significant heat. This heat production can cause various environmental issues, such as the release of volatile organic compounds, an increased risk of groundwater contamination from leachate migration, unpleasant odors, and a reduction in the structural integrity of the landfill liner. Therefore, efficient heat mitigation methods in landfill liners are crucial for minimizing detrimental environmental effects. Utilizing insulation material in landfills can be an effective and novel method in the environmental geotechnical field while promoting material sustainability. This study aims to evaluate the effectiveness of rockwool as an insulation material in reducing heat transfer inside landfill liners. The effectiveness of rockwool was assessed by using both physical and numerical modelling with varying thicknesses of rockwool, moisture conditions, and elevated temperatures in the landfill liner system. The insulated landfill liner system was simulated numerically using ANSYS software. A wooden box prototype was built to simulate a real-life insulated landfill liner system to evaluate the feasibility of insulation material as a heat mitigation method in landfills. The findings suggest that rockwool is effective in mitigating the heat in landfill liners. Overall, rockwool reduced the elevated temperatures up to 48.45% despite the system being wet which reduces the effectiveness of insulation performance. Comparatively, the 20 mm rockwool was efficient in minimizing average level of elevated temperatures, meanwhile, rockwool with thicknesses of 35 mm and 50 mm were needed to attenuate extremely elevated temperatures. These results were demonstrated through numerical simulation and validated by physical modelling results. It can imply an effective method for mitigating heat in landfill liners, which advances the development of environmental geotechnics for sustainable waste management.

Identification and Antifungal Susceptibility Pattern of Candida Isolates Recovered from Urine and Blood Specimens from Patients Admitted in Wards of a Tertiary Care Hospital, North Delhi Jain, Sanjay; Khatri, Shilpa; Kumar, Manoj; Bharara, Tanisha; Yadav, Abhishek
Journal of Epidemiology and Public Health Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.02.08

Background: Candida species are responsible for various clinical infections ranging from mucocutaneous infection to life-threatening invasive diseases. Increased resistance to antifungal drugs during the last decade has become a serious concern. Therefore, identification of Candida up to species level and its antifungal susceptibility testing is very important in the management of Candida infections. This study aimed to identify these organisms and study their susceptibility patterns.Subjects and Method: A retrospective study was conducted over 9 months (July 2022 to March 2023) from urine and blood samples collected from 80 IPD patients admitted to various wards of Hindu Rao Hospital. The samples were selected based on their growth on blood agar. The variables of interest are the different species of Candida and susceptibility to antibiotics. Identification of Candida species was done by Gram stain, Germ tube formation test, color on HiCrome Candida agar medium, chlamydospore formation on corn meal agar, and VITEK 2 Compact System. The MICs were interpreted according to the CLSI guidelines 2022.Results: 47 and 33 of urine and blood cultures were positive for Candida species respectively. Most of the isolates were from the Paediatric ward (28.75%), followed by the Medicine ward (27.5%). The most common species was C. tropicalis (56.25%) followed by C. albicans (23.75%). Most species of Candida were sensitive to amphotericin B, fluconazole, voriconazole, caspofungin, micafungin, and flucytosine except Candida albicans which showed 100% resistance to amphotericin B and Candida krusei which showed 66% sensitivity to voriconazole and 33% to caspofungin.Conclusion: Candida colonization has a considerable prevalence among patients hospitalized in our hospital. The species identification of Candida isolates along with their antifungal susceptibility pattern can help the clinician in better treatment of patients with candiduria and candidemia. Keywords: Candida, bloodstream infection, minimum inhibitory concentration

Prevalence of Infections Caused by Hepatitis B Virus, Hepatitis C Virus and Their Co-Infection in A Tertiary Care Centre, Delhi, India Kumar, Manoj; Jain, Sanjay
Journal of Epidemiology and Public Health Vol. 10 No. 1 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2025.10.01.08

Background: Hepatitis B and C are the most dominant causes of viral hepatitis, leading to both acute and chronic infections. This study was done to determine the magnitude of the prevalence of Hepatitis B and C and their co-infection.Subjects and Method: A retrospective cross-sectional observational study was conducted in the Department of Microbiology, North DMC Medical College and Hindu Rao Hospital, Delhi, India from July 2023 to June 2024. All blood samples received from indoor and outdoor patients from all departments were tested by Monolisa HBsAg Ultra and anti-HCV(Ag-Ab Ultra V2) Monolisa by ELISA method. The variables studied were age, sex, in-patient/out-patient, and type of ward. The data was analyzed using the Chi-Square test and Mann-Whitney test.Results: Of a total of 20,000 blood samples received, 5,358(26.80%) samples were from inpatient department/IPD (2,210 female, 3,148 male) and 14642 (73.20%) and outpatient department/OPD (9,201 female, 5,441 male). 422 samples (2.11%) were positive for HBsAg (210 IPD -77 female, 133 male; 212 OPD - 121 female, 91 male) and 614 (3.07%) for anti-HCV (408 IPD - 135 female, 273 male; 206 OPD - 100 female, 106 male). Co-infection of Hepatitis B and C viruses was seen in 40 patients, 31 IPD (10 female, 21 male) and 9 OPD (1 female, 8 male). Maximum cases were seen from medicine wards among IPD patients of HBsAg positive, anti-HCV positive, and co-infection and in the age group 41-60 years in all three categories.Conclusion: Screening for HBV and HCV infection is compulsory so that preventive measures are implemented to improve public health.

The Neutrophil Percentage-to-Albumin Ratio (NPAR) is Associated with In-Hospital Mortality in Patients with Liver Cirrhosis Lastiana, Ni Made Putri; Mariadi, Ketut; Sindhughosa, Dwijo Anargha; Kumar, Manoj
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 2 (2025): VOLUME 26, NUMBER 2, AGUSTUS, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2622025101-106

Background: Studies show that the Neutrophil Percentage-to-Albumin Ratio (NPAR) predicts mortality in a number of illnesses. On the other hand, there is currently limited clinical support for using NPAR in liver cirrhosis patients. Investigating the associated of NPAR and hospital mortality outcome patients with liver cirrhosis is the goal of this study.Methods: All cirrhosis patients who were admitted to the hospital were included in this retrospective cohort analysis. The percentage of neutrophils and albumin levels on the first day of hospitalization were compared to determine the NPAR. Data were analyzed using the Mann-Whitney test, operating curve (ROC) analysis, and Kaplan-Meier survival curves. P-value 0.05 was considered statistically significant. Results: This study included 98 patients with liver cirrhosis. It was found that NPAR had a high incidence of patient mortality compared to surviving patients who were hospitalised (35.13 vs. 25.33, p 0.001). The median overall survival for all subjects was 10 days, indicating that 50% of the subjects had died within 10 days. According to ROC analysis, NPAR has an ideal cutoff value of 29.63 and can be utilized as a predictor of in-hospital mortality (sensitivity 74.1%, specificity 72.7%, AUC 0.8, p 0.001). Survival analysis stratified by NPAR showed that patients with NPAR ≥ 29.63 had a lower median survival compared to those with NPAR 29.6.Conclusion: In patients with liver cirrhosis, the Neutrophil Percentage-to-Albumin Ratio (NPAR) is a metric that can be used to assess in-hospital mortality outcomes

Identification and Antifungal Susceptibility Pattern of Candida Isolates Recovered from Urine and Blood Specimens from Patients Admitted in Wards of a Tertiary Care Hospital, North Delhi Jain, Sanjay; Khatri, Shilpa; Kumar, Manoj; Bharara, Tanisha; Yadav, Abhishek
Journal of Epidemiology and Public Health Vol. 9 No. 2 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2024.09.02.08

Background: Candida species are responsible for various clinical infections ranging from mucocutaneous infection to life-threatening invasive diseases. Increased resistance to antifungal drugs during the last decade has become a serious concern. Therefore, identification of Candida up to species level and its antifungal susceptibility testing is very important in the management of Candida infections. This study aimed to identify these organisms and study their susceptibility patterns.Subjects and Method: A retrospective study was conducted over 9 months (July 2022 to March 2023) from urine and blood samples collected from 80 IPD patients admitted to various wards of Hindu Rao Hospital. The samples were selected based on their growth on blood agar. The variables of interest are the different species of Candida and susceptibility to antibiotics. Identification of Candida species was done by Gram stain, Germ tube formation test, color on HiCrome Candida agar medium, chlamydospore formation on corn meal agar, and VITEK 2 Compact System. The MICs were interpreted according to the CLSI guidelines 2022.Results: 47 and 33 of urine and blood cultures were positive for Candida species respectively. Most of the isolates were from the Paediatric ward (28.75%), followed by the Medicine ward (27.5%). The most common species was C. tropicalis (56.25%) followed by C. albicans (23.75%). Most species of Candida were sensitive to amphotericin B, fluconazole, voriconazole, caspofungin, micafungin, and flucytosine except Candida albicans which showed 100% resistance to amphotericin B and Candida krusei which showed 66% sensitivity to voriconazole and 33% to caspofungin.Conclusion: Candida colonization has a considerable prevalence among patients hospitalized in our hospital. The species identification of Candida isolates along with their antifungal susceptibility pattern can help the clinician in better treatment of patients with candiduria and candidemia. Keywords: Candida, bloodstream infection, minimum inhibitory concentration

Prevalence of Infections Caused by Hepatitis B Virus, Hepatitis C Virus and Their Co-Infection in A Tertiary Care Centre, Delhi, India Kumar, Manoj; Jain, Sanjay
Journal of Epidemiology and Public Health Vol. 10 No. 1 (2025)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2025.10.01.08

Background: Hepatitis B and C are the most dominant causes of viral hepatitis, leading to both acute and chronic infections. This study was done to determine the magnitude of the prevalence of Hepatitis B and C and their co-infection.Subjects and Method: A retrospective cross-sectional observational study was conducted in the Department of Microbiology, North DMC Medical College and Hindu Rao Hospital, Delhi, India from July 2023 to June 2024. All blood samples received from indoor and outdoor patients from all departments were tested by Monolisa HBsAg Ultra and anti-HCV(Ag-Ab Ultra V2) Monolisa by ELISA method. The variables studied were age, sex, in-patient/out-patient, and type of ward. The data was analyzed using the Chi-Square test and Mann-Whitney test.Results: Of a total of 20,000 blood samples received, 5,358(26.80%) samples were from inpatient department/IPD (2,210 female, 3,148 male) and 14642 (73.20%) and outpatient department/OPD (9,201 female, 5,441 male). 422 samples (2.11%) were positive for HBsAg (210 IPD -77 female, 133 male; 212 OPD - 121 female, 91 male) and 614 (3.07%) for anti-HCV (408 IPD - 135 female, 273 male; 206 OPD - 100 female, 106 male). Co-infection of Hepatitis B and C viruses was seen in 40 patients, 31 IPD (10 female, 21 male) and 9 OPD (1 female, 8 male). Maximum cases were seen from medicine wards among IPD patients of HBsAg positive, anti-HCV positive, and co-infection and in the age group 41-60 years in all three categories.Conclusion: Screening for HBV and HCV infection is compulsory so that preventive measures are implemented to improve public health.

Analytical Solution of Equations Governing Aligned Plane Rotating Magnetohydrodynamic Fluid Through Porous Media by Martin’s Method Birendra, Birendra Kumar Vishwakarma; Sil, Sayantan; Kumar, Manoj
Journal of the Indonesian Mathematical Society VOLUME 30 NUMBER 1 (MARCH 2024)
Publisher : IndoMS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22342/jims.30.1.1356.40-62

This investigation is an approach to setup an analytical solution of steady plane allied MHD fluid flow having infinite electrical conductivity in a rotating frame through porous media by Martin’s method. The governing non-linearequations of the fluid flow are transformed into a new form called Martin’s form by employing differential geometry where the curvilinear co-ordinates (Φ, Ψ) in the plane of flow shows that, the co-ordinate lines Ψ are the streamlines of flow and the co-ordinate lines Φ are arbitrary constants. Exact solution is obtained and velocity,vorticity, current density magnetic field and pressure distribution are found out. Also, the diagrams have been plotted to sketch the streamline patterns and to study variation of pressure function with angular velocity.

Implementation of Game-Based Learning in Improving Learning Motivation of Elementary School Students Kumar, Manoj; Chang, Xin Wei; Faqh, Ameer
International Journal of Educational Insights and Innovations Vol. 1 No. 1 (2024): September 2024 - International Journal of Educational Insights and Innovations
Publisher : PT. Technology Laboratories Indonesia (TechnoLabs)

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This study aims to explore the effect of Game-Based Learning (GBL) implementation on students' learning motivation in primary schools. GBL is a learning approach that integrates game elements into the teaching and learning process, designed to increase student engagement and motivation. In the context of primary education, learning motivation is an important factor that contributes to students' academic success. The research method used was a pseudo-experiment with a pretest-posttest control group design. The research sample consisted of 80 fourth grade students in one elementary school who were divided into two groups, namely the experimental group using GBL and the control group using conventional learning methods. Data regarding students' learning motivation was collected through a learning motivation questionnaire adapted from a standardized learning motivation scale. The results of the data analysis showed that there was a significant increase in the learning motivation of students using GBL compared to the control group. The average learning motivation score in the experimental group increased significantly after the implementation of GBL, with a p value <0.05. These findings suggest that GBL is effective in increasing students' learning motivation in primary schools. This study suggests that GBL can be integrated into the learning curriculum in primary schools as one of the strategies to increase students' learning motivation. In addition, further research is recommended to explore various other aspects of GBL, such as its impact on students' learning outcomes and social skills.

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