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Tea Constituent in Protecting Glyphosate Effect on Human Breast Cancers Cells (MCF-7) Growth Batubara, Irmanida; Suprihatini, Rohayati; Mariya, Silmi; Achmadi, Suminar Setiati; Sokoastri, Valentina; Mulyatni, Agustin Sri; Hakim, Arif Rakhman
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 9, No. 2, November 2023
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v9i2.33229

Abstract

Glyphosate, which has been documented as a contaminant in tea, promotes the proliferation of human breast cancer cells (MCF-7). Tea, on the other hand, includes various antioxidants, including epigallocatechin gallate (EGCG), which may protect against cancer cell proliferation. The purpose of this research is to determine the preventive effect of concentrated brewed green tea on MCF-7 development caused by glyphosate. The glyphosate concentration that promotes MCF-7 development was determined using a serial concentration of glyphosate. Glyphosate concentrations of up to 64 mg/L were shown to have no effect on MCF-7 cell proliferation. Concentrated brewed tea and EGCG 200 mg/L have the potential to suppress MCF-7 cell proliferation in the presence of glyphosate up to 512 mg/L. The combination of glyphosate and concentrated brewed tea or EGCG protects against glyphosate toxicity via altering the expression of tumor suppressor protein (p53).
Studi Preferensi Kumbang Lepidiota stigma F. (Coleoptera: Scarabaeidae) Terhadap Berbagai Sumber Cahaya Perangkap dan Tanaman Di Sekitar Kebun Tebu Achadian, Etik Mar'ati; Mulyatni, Agustin Sri; Saputra, Deddy Praditya; Putra, Anandya; Kardianasari, Alfarina
Indonesian Sugar Research Journal Vol 5, No 1 (2025): Indonesian Sugar Research Journal
Publisher : Pusat Penelitian Perkebunan Gula Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54256/isrj.v5i1.140

Abstract

Penggunaan perangkap cahaya (light trap) untuk monitoring dan pengendalian populasi kumbang Lepidiota stigma sangat membantu menekan populasi hama uret. Karena itu tujuan dari penelitian ini ialah mengamati ketertarikan kumbang L. stigma terhadap beberapa sumber cahaya perangkap dan tanaman di sekitar kebun. Pengamatan dilakukan di petak M7, M13, M15 dan M28, Kebun Sumberlumbu serta petak J24 Kebun Onggoboyo, Kediri pada musim tanam 2024/2025. Sumber cahaya perangkap yang digunakan ialah lampu spotlight halogen, lampu Self ballasted High-pressure Mercury Vapour (SHMV), lampu Merkuri, lampu LED dan lampu darurat. Hasil pengamatan menunjukkan kumbang lebih tertarik pada sumber cahaya dari jenis lampu spotlight halogen. Kumbang L. stigma hinggap dan makan dedaunan dari beberapa pepohonan diantaranya asam (Tamarindus indica), rumput gajah (Pennisetum purpureum), trembesi (Samanea saman), kembang telekan (Lantana camara) dan petai (Parkia speciosa).
Effect of combination of organosulfur and polyphenols organic fungicide on Ganoderma-infected oil palm seedlings Yusup, Ciptadi Achmad; Eris, Deden Dewantara; Mulyatni, Agustin Sri; Pradana, Mahardika Gama; Widiastuti, Happy; Santoso, Djoko
Jurnal Hama dan Penyakit Tumbuhan Tropika Vol. 26 No. 1 (2026): MARCH, JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA: JOURNAL OF TROPICAL PLANT PE
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jhptt.126136-146

Abstract

The curative potential of an organic fungicide against Ganoderma boninense was previously assessed in vitro and yielded promising results. This organic fungicide was formulated using a combination of organosulfur compounds and polyphenols (OSC-P) as active ingredients. This study aimed to evaluate the effectiveness of OSC-P application in controlling basal stem rot (BSR) disease in infected oil palm seedlings of different varieties and to determine the optimum application dose. Two oil palm varieties were used: a G. boninense-susceptible variety and a moderately tolerant variety. The seedlings were artificially infected with G. boninense using inoculated rubber wood blocks (RWB). OSC-P was applied to 16-week-old seedlings by soil drenching at a volume of 200 mL per plant at 2-week intervals for 24 weeks. A total of six treatments, including controls, were arranged with four replications and observed at 4-week intervals. Each replication consisted of 10 seedlings. Observed parameters included disease incidence, disease severity, and vegetative growth parameters. The results showed that OSC-P application significantly reduced the incidence and severity of BSR disease in infected oil palm seedlings. BSR symptoms were less severe in the moderately tolerant variety than in the susceptible variety; however, disease incidence did not differ significantly between the two varieties. The optimum application dose of OSC-P was 0.8% (v/v), and variations in application dose did not significantly affect disease incidence or severity at 24 weeks after application. These findings are expected to complement existing preventive strategies for BSR management.