Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Journal of Food and Pharmaceutical Science Journal of Food and Pharmaceutical Sciences
Mikhania Christiningtyas Eryani
Master of Pharmacy Study Program, Faculty of Pharmacy, Universitas Jember, Jember, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Formulation and Characterization of Curcumin Micellar Powder Sublingual Tablets Nina Wijiani; Helmy Yusuf; Dewi Isadiartuti; Mikhania Christiningtyas Eryani
Journal of Food and Pharmaceutical Sciences Vol 14, No 4 (2026): J.Food.Pharm.Sci (In Press)
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.28325

Abstract

Curcumin is the most active compound contained in turmeric rhizome (Curcuma longa). Curcumin has low solubility in water, which affects its bioavailability. Efforts to increase curcumin solubility are made in micelle systems. However, micelle solutions have the short shelf life, so they need to be to be converted to dry micelle powder by spray drying. Curcumin micelle powder was formulated into sublingual tablets to provide a convenient dosage form, which may improve patient compliance due to ease of administration and avoidance of swallowing difficulties. This study aims to manufacture sublingual tablets containing curcumin micelles prepared with varying concentrations of sucrose and casein and to characterize them. Tablets were prepared by direct compression method. Tablet characterization carried out included tablet hardness, tablet friability, tablet disintegration time, and dissolution. The results showed that all formulas met the requirements for hardness, friability, disintegration time, and dissolution. This study concludes that variations in casein and sucrose concentrations affect the friability, disintegration time, and dissolution of sublingual tablets but do not affect tablet hardness.
Formulation and Characterization of Curcumin Micellar Powder Sublingual Tablets Nina Wijiani; Helmy Yusuf; Dewi Isadiartuti; Mikhania Christiningtyas Eryani
Journal of Food and Pharmaceutical Sciences Vol 14, No 4 (2026): J.Food.Pharm.Sci (In Press)
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.28325

Abstract

Curcumin is the most active compound contained in turmeric rhizome (Curcuma longa). Curcumin has low solubility in water, which affects its bioavailability. Efforts to increase curcumin solubility are made in micelle systems. However, micelle solutions have the short shelf life, so they need to be to be converted to dry micelle powder by spray drying. Curcumin micelle powder was formulated into sublingual tablets to provide a convenient dosage form, which may improve patient compliance due to ease of administration and avoidance of swallowing difficulties. This study aims to manufacture sublingual tablets containing curcumin micelles prepared with varying concentrations of sucrose and casein and to characterize them. Tablets were prepared by direct compression method. Tablet characterization carried out included tablet hardness, tablet friability, tablet disintegration time, and dissolution. The results showed that all formulas met the requirements for hardness, friability, disintegration time, and dissolution. This study concludes that variations in casein and sucrose concentrations affect the friability, disintegration time, and dissolution of sublingual tablets but do not affect tablet hardness.
Co-Authors Dewi Isadiartuti Helmy Yusuf Nina Wijiani