Micro, small, and medium enterprises (MSMEs) play a strategic role in the Indonesian economy by absorbing labor, supporting economic growth, and promoting equitable community welfare. However, improving MSME performance remains an important challenge, particularly in ensuring that internal organizational factors can effectively support productivity, operational efficiency, and customer satisfaction. This study aimed to examine the effects of organizational culture and organizational behavior on MSME performance in Makassar City. A quantitative research approach was employed using primary data collected through questionnaires distributed to 100 MSMEs in Makassar City. The data were analyzed using descriptive statistical analysis and Statistical Package for the Social Sciences (SPSS) version 27.00. The results showed that organizational culture had a positive and significant effect on MSME performance, indicating that better implementation of organizational culture was associated with higher productivity, operational efficiency, and customer satisfaction. Organizational behavior also had a positive and significant effect on MSME performance, demonstrating that effective organizational behavior further improved productivity, operational efficiency, and customer satisfaction. These findings indicate that organizational culture and organizational behavior are important internal factors in strengthening MSME performance. The study contributes to the understanding of organizational factors that support MSME development and provides practical implications for MSME owners and managers in developing a supportive organizational culture and effective behavior to improve performance and competitiveness in Makassar City.