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All Journal TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Sehat Rakyat: Jurnal Kesehatan Masyarakat Indonesian Journal of Health Research Innovation
Arifiani Agustin Amalia
Universitas 'Aisyiyah Yogyakarta
Humanities Computer Science & IT Dentistry Engineering Health Professions Medicine & Pharmacology Nursing Public Health Veterinary Other

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HUBUNGAN KADAR SGOT DAN SGPT DENGAN JUMLAH TROMBOSIT PADA PASIEN DEMAM BERDARAH DENGUE DI RUMAH SAKIT NURHIDAYAH Rena Rahmaliani Tsalits; Joko Murdiyanto; Arifiani Agustin Amalia
Indonesian Journal of Health Research Innovation Vol. 3 No. 3 (2026): Indonesian Journal of Health Research Innovation
Publisher : Yayasan Menawan Cerdas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64094/affedd53

Abstract

Demam Berdarah Dengue (DBD) masih menjadi masalah kesehatan masyarakat. Trombositopenia dan peningkatan kadar SGOT serta SGPT merupakan temuan laboratorium yang sering dijumpai pada pasien DBD. Penelitian ini bertujuan menganalisis hubungan kadar SGOT dan SGPT dengan jumlah trombosit pada pasien DBD di Rumah Sakit Nurhidayah. Penelitian observasional analitik ini menggunakan desain cross-sectional dan data sekunder rekam medis. Sebanyak 50 pasien dipilih menggunakan purposive sampling. Data dianalisis secara deskriptif, dilanjutkan dengan uji Shapiro-Wilk, korelasi Spearman, dan regresi linear berganda pada α=0,05. Rerata kadar SGOT, SGPT, dan jumlah trombosit masing-masing sebesar 165,74±41,52 U/L, 102,76±14,15 U/L, dan 37,36±19,11 ×10³/µL. SGOT (rₛ=-0,761; p<0,001) dan SGPT (rₛ=-0,540; p<0,001) berkorelasi negatif dengan jumlah trombosit. Model regresi signifikan (F=34,729; p<0,001; R²=0,596). Dalam model multivariat, SGOT berhubungan dengan jumlah trombosit (B=-0,458; 95% CI=-0,615 hingga -0,301; p<0,001), sedangkan SGPT tidak signifikan (B=0,401; 95% CI=-0,064 hingga 0,866; p=0,090). SGOT dan SGPT berkorelasi negatif dengan jumlah trombosit, tetapi hanya SGOT yang tetap signifikan dalam model multivariat.
Hubungan Kadar Kolesterol Total dengan Tekanan Darah pada Penderita Diabetes Mellitus Tipe 2 Layanan Kesehatan Primer Putri Amellia Sari; Chairil Anwar; Arifiani Agustin Amalia
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2026): Agustus 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i3.8192

Abstract

Type 2 Diabetes Mellitus (T2DM) was a chronic metabolic disease characterized by hyperglycemia caused by insulin resistance and impaired insulin secretion. This condition is often accompanied by dyslipidemia, which may increase the risk of atherosclerosis and changes in blood pressure. This reseach was purposelly to established the relation among total cholesterol grades also blood pressure in patients with T2DM at Mantrijeron Community Health Center. This reseach was analyzing observational design with a cross-sectional approach use secondary data included from the medical records of T2DM patients from June to December 2025. The reseach population total of 105 patients, also amount 67 patients who met the inclusion and exclusion criteria were selecting using purposive sampling. The respondents were predominantly aged 45–54 years (53.73%) and female (82.09%). Data were analyzing use the Kolmogorov–Smirnov normality test and Spearman correlation test. The yields shown that most respondents has normal total cholesterol grades (<200 mg/dL), accounting for 45 patients (67.16%), systolic blood pressure in the prehypertension category, accounting for 45 patients (67.16%), and normal diastolic blood pressure (≤80 mmHg), accounting for 29 patients (43.38%). The correlation analysis shown that dont has significant relation among total cholesterol grades also systolic blood pressure (p = 0.645) or diastolic blood pressure (p = 0.658). the yields was including total cholesterol grades dont has significantly associated with either systolic or diastolic blood pressure in patients with T2DM at Mantrijeron Community Health Center.
Analisis IQC dan Sigma Metrik Pemeriksaan Bilirubin Total Level Normal di RS Tipe C Kota Yogyakarta Nia Wulandari; Havida Widyastuti; Arifiani Agustin Amalia
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 7, No 3 (2026)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v7i3.16588

Abstract

Background: The implementation of Internal Quality Control is crucial in clinical laboratories to ensure the accuracy and precision of test results, particularly for total bilirubin, which serves as an indicator of hepatobiliary disorders. Objective: This study aimed to analyze Internal Quality Control and sigma metrics for normal-level total bilirubin testing at a Type C hospital in Yogyakarta City by evaluating accuracy, precision, Levey-Jennings charts based on Westgard rules, and sigma metric values. Methods: This was a descriptive study with a quantitative approach utilizing secondary data from A total of 181 daily QC results from January–June 2025 were analyzed. Total sampling was employed. Data were processed using Microsoft Excel to calculate the mean, standard deviation (SD), Coefficient of Variation (CV%), bias (d%), and sigma metric values based on the 2024 CLIA Total Allowable Error (TEa) of 20%. Results: The Coefficient of Variation (CV%) values from January to June were 16.66%, 9.80%, 11.76%, 5.88%, 13.72%, and 10.78%, respectively. Only April met the precision criterion (CV ≤7%). Bias (d%) values were 8.62%, 9.80%, 8.82%, 10.59%, 11.76%, and 7.84%, respectively; all values fell below the Total Allowable Error (TEa) limit, indicating acceptable testing accuracy. Levey-Jennings charts revealed violations of the Westgard 1₂s rule from February to June and the 1₃s rule in May. Sigma metric values from January to June were 0.72, 1.04, 0.95, 1.56, 0.60, and 0.85, respectively. All results fell into the <3 sigma category. Conclusion: Total bilirubin testing demonstrated acceptable accuracy, yet precision was suboptimal. Evaluation of Levey-Jennings charts and sigma metric values indicates that the Internal Quality Control process requires improvement.
Perbandingan Kadar Trigliserida Postprandial 4 Jam Setelah Konsumsi Nasi Rendang pada Dewasa Muda Sehat Rizky Aguspriyanto Hasan; Arifiani Agustin Amalia; Joko Murdiyanto
TRILOGI: Jurnal Ilmu Teknologi, Kesehatan, dan Humaniora Vol 7, No 3 (2026)
Publisher : Universitas Nurul Jadid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33650/trilogi.v7i3.16211

Abstract

Consumption of high-fat meals can increase postprandial triglyceride levels, although the magnitude of the response varies among individuals. Continuous elevation of triglyceride levels may increase the risk of lipid metabolism disorders and cardiovascular diseases. This study aimed to determine the difference in triglyceride levels before and after the consumption of a high-fat meal consisting of one serving of Nasi Padang with rendang, containing approximately 8–12 g of fat, in healthy adult subjects. This study used a pre-experimental method with a one group pretest-posttest design. The sample consisted of 36 respondents selected using a purposive sampling technique. Triglyceride levels were measured before high-fat food consumption and 4 hours after consumption using the GPO-PAP method. Data were analyzed using the Shappiro-Wilk normality test and Paired t-test. The results showed that the mean triglyceride level before consumption of high-fat food was 134.58 ± 13,09 mg/dL and increased to 147.97 ± 12,56 mg/dL after 4 hours of consumption. The average increase in triglyceride levels was 13.39 mg/dL with an increase range of 5–27 mg/dL. The Paired t-test result showed a significance value of 0.000 (p<0.05), indicating that there was a significant difference in triglyceride levels before and after consumption of high-fat food among healthy adults.
Co-Authors Chairil Anwar Havida Widyastuti murdiyanto, joko Nia Wulandari Putri Amellia Sari Rena Rahmaliani Tsalits Rizky Aguspriyanto Hasan