Arifiani Agustin Amalia
Universitas 'Aisyiyah Yogyakarta

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HUBUNGAN KADAR SGOT DAN SGPT DENGAN JUMLAH TROMBOSIT PADA PASIEN DEMAM BERDARAH DENGUE DI RUMAH SAKIT NURHIDAYAH Rena Rahmaliani Tsalits; Joko Murdiyanto; Arifiani Agustin Amalia
Indonesian Journal of Health Research Innovation Vol. 3 No. 3 (2026): Indonesian Journal of Health Research Innovation
Publisher : Yayasan Menawan Cerdas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64094/affedd53

Abstract

Demam Berdarah Dengue (DBD) masih menjadi masalah kesehatan masyarakat. Trombositopenia dan peningkatan kadar SGOT serta SGPT merupakan temuan laboratorium yang sering dijumpai pada pasien DBD. Penelitian ini bertujuan menganalisis hubungan kadar SGOT dan SGPT dengan jumlah trombosit pada pasien DBD di Rumah Sakit Nurhidayah. Penelitian observasional analitik ini menggunakan desain cross-sectional dan data sekunder rekam medis. Sebanyak 50 pasien dipilih menggunakan purposive sampling. Data dianalisis secara deskriptif, dilanjutkan dengan uji Shapiro-Wilk, korelasi Spearman, dan regresi linear berganda pada α=0,05. Rerata kadar SGOT, SGPT, dan jumlah trombosit masing-masing sebesar 165,74±41,52 U/L, 102,76±14,15 U/L, dan 37,36±19,11 ×10³/µL. SGOT (rₛ=-0,761; p<0,001) dan SGPT (rₛ=-0,540; p<0,001) berkorelasi negatif dengan jumlah trombosit. Model regresi signifikan (F=34,729; p<0,001; R²=0,596). Dalam model multivariat, SGOT berhubungan dengan jumlah trombosit (B=-0,458; 95% CI=-0,615 hingga -0,301; p<0,001), sedangkan SGPT tidak signifikan (B=0,401; 95% CI=-0,064 hingga 0,866; p=0,090). SGOT dan SGPT berkorelasi negatif dengan jumlah trombosit, tetapi hanya SGOT yang tetap signifikan dalam model multivariat.
Hubungan Kadar Kolesterol Total dengan Tekanan Darah pada Penderita Diabetes Mellitus Tipe 2 Layanan Kesehatan Primer Putri Amellia Sari; Chairil Anwar; Arifiani Agustin Amalia
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2026): Agustus 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i3.8192

Abstract

Type 2 Diabetes Mellitus (T2DM) was a chronic metabolic disease characterized by hyperglycemia caused by insulin resistance and impaired insulin secretion. This condition is often accompanied by dyslipidemia, which may increase the risk of atherosclerosis and changes in blood pressure. This reseach was purposelly to established the relation among total cholesterol grades also blood pressure in patients with T2DM at Mantrijeron Community Health Center. This reseach was analyzing observational design with a cross-sectional approach use secondary data included from the medical records of T2DM patients from June to December 2025. The reseach population total of 105 patients, also amount 67 patients who met the inclusion and exclusion criteria were selecting using purposive sampling. The respondents were predominantly aged 45–54 years (53.73%) and female (82.09%). Data were analyzing use the Kolmogorov–Smirnov normality test and Spearman correlation test. The yields shown that most respondents has normal total cholesterol grades (<200 mg/dL), accounting for 45 patients (67.16%), systolic blood pressure in the prehypertension category, accounting for 45 patients (67.16%), and normal diastolic blood pressure (≤80 mmHg), accounting for 29 patients (43.38%). The correlation analysis shown that dont has significant relation among total cholesterol grades also systolic blood pressure (p = 0.645) or diastolic blood pressure (p = 0.658). the yields was including total cholesterol grades dont has significantly associated with either systolic or diastolic blood pressure in patients with T2DM at Mantrijeron Community Health Center.