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All Journal JOURNAL OF Pharmacy and Tropical Issues
Theodora Liefanda Bunga
Universitas Nusa Cendana
Medicine & Pharmacology

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Penentuan kadar metabolit sekunder dan aktivitas antioksidan ekstrak faloak (Sterculia quadrifida R.Br.) Theodora Liefanda Bunga; Muhajirin Dean; Mathias N. Kolobani; Muntasir Muntasir
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 4 (2026): August edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Sarjana Farmasi Indonesia (ISFI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i4.3982

Abstract

Background: Faloak (Sterculia quadrifida R.Br.) is a medicinal plant native to East Nusa Tenggara that has potential as an antioxidant. Purpose: To determine total flavonoid, tannin, and phenolic contents of 95% ethanol and aqueous extracts of faloak root bark, stem bark, and twigs, and to evaluate antioxidant activity of selected extract. Method: This quantitative descriptive-exploratory research used maceration (95% ethanol) and decoction (water) methods. Metabolite contents were determined spectrophotometrically, while antioxidant activity was tested using the DPPH method ( ). Results: Highest secondary metabolite content was consistently found in the twigs. In the 95% ethanol extract, flavonoid, tannin, and phenolic contents of twigs were 0.7495, 38.8472, and 94.2777 mg/g extract, respectively, while in aqueous extract, they were 0.8093, 31.6775, and 59.7342 mg/g extract. 95% ethanol extract was selected as superior extract because it yielded higher metabolite levels than aqueous extract. DPPH testing showed  values for root bark, stem bark, and twigs of 26.502, 36.110, and 21.524 ppm, respectively, classifying all samples into very strong antioxidant category. Conclusion: Flavonoid, tannin, and phenolic contents vary depending on the plant part and solvent type. Faloak twigs possess highest metabolite content and most potent antioxidant activity.   Keywords: Antioxidant; Faloak; Metabolites; Sterculia Quadrifida R.Br.
Co-Authors Mathias N. Kolobani Muntasir, Muntasir