The adjustment of students living away from home is an individual's ability to face and overcome demands from within themselves and the environment in order to achieve balance in life. One factor suspected to play a role is self-disclosure, namely the ability of individuals to express thoughts, feelings, experiences, and information about themselves to others. This study aims to determine the effect of self-disclosure on the adjustment of students living away from home from Eastern Indonesia in Jakarta. The study used a quantitative approach with a predictive correlational design. The research sample consisted of 200 students living away from home from Eastern Indonesia in Jakarta, selected through purposive sampling. Data collection used a Likert-model psychological scale, namely a self-disclosure scale arranged based on aspects of self-disclosure and a self-adjustment scale arranged based on aspects of self-adjustment. Data analysis used simple linear regression with the help of SPSS 25. The results showed that self-disclosure had a positive and significant effect on adjustment, with F = 20.637 and p = 0.000 (p < 0.05). The regression equation obtained was Y = 88.835 + 0.948X, and the standardized coefficient (β) of 0.307 indicates that the higher the self-disclosure, the higher the adjustment. Self-disclosure contributed 9.4% to self-adjustment (R Square = 0.094), while the remaining 90.6% was related to other factors that were not studied, such as environmental conditions, social support, self-esteem, personal experience, personality, and individual capacity to cope with change.