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Mudzakir Taufiqurrahman
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NEPHROPROTECTIVE EFFECT OF GARLIC CHIVES (Allium tuberosum) ON BUN AND CREATININE LEVELS OF WISTAR RATS INDUCED BY DOXORUBICIN Erfan Efend; Fuad Adi Prasetyo; Mudzakir Taufiqurrahman; Kiky Martha Ariesaka; Ain Yuanita Insani; Brilliant Givya Ariansari
NurseLine Journal Vol. 1 No. 2 (2016): November 2016
Publisher : Program Studi Ilmu Keperawatan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v1i2.60086

Abstract

Cancer is the most leading disease that cause of death. Doxorubicin chemotherapy is often used in cancer treatment, because of its effectiveness. Although doxorubi cin has a positive effect for killing cancer cell, doxorubicin has many side effects, one of which doxorubicin can cause kidney damage through the process of inter stitial fibrosis. Utilization garlic chives ex-tract as co chemotherapy to reduce renal damage induced by doxorubicin is a prospective opportunities. This study aimed toanalyze the effect of garlic chives extract as a nephropro-tective on levels of BUN and creatinine of wistar rats induced by doxorubicin. The research method was quasi experimental design with post test only randomized controlled group. Theresults showed that extracts of garlic chives can reduce levels of BUN and creati nine (p <0.05) in the group that only induced by doxorubicin. In conclusion, ex tract of garlic chives has nephroprotecive effects on wistar rats which were in duced by doxorubicin
Co-Authors Ain Yuanita Insani Brilliant Givya Ariansari Erfan Efend Fuad Adi Prasetyo Kiky Martha Ariesaka