<![CDATA[Nurses' compliance with the use of personal protective equipment (PPE) is a critical component of infection prevention and the protection of healthcare workers from occupational hazards. However, PPE compliance remains inconsistent and is influenced by various individual, organizational, and workplace factors. This study aimed to map the available scientific evidence regarding the determinants of nurses' compliance with PPE use in hospital settings. A scoping review was conducted following the PRISMA Extension for Scoping Reviews (PRISMA-ScR) guidelines. A systematic literature search was performed using PubMed, Scopus, ScienceDirect, SpringerLink, Google Scholar, and Garuda. Search terms related to nurses, personal protective equipment, compliance, determinants, and hospitals were combined using Boolean operators (AND/OR). Articles published between 2022 and 2026 in either English or Indonesian were screened according to predefined inclusion and exclusion criteria. Data were extracted, synthesized narratively, and the methodological quality of the included studies was assessed using the Critical Appraisal Skills Programme (CASP). A total of 19 studies met the inclusion criteria. The findings indicated that nurses' PPE compliance is influenced by multiple factors. Individual determinants included knowledge, attitudes, risk perception, self-efficacy, work experience, and motivation. Organizational determinants comprised PPE availability, infection prevention training, hospital policies, leadership support, supervision, and safety culture. Workplace factors, such as workload, staff shortages, and patient overcrowding, also affected compliance. Overall, organizational support and continuous training emerged as the most consistent factors associated with improved PPE compliance. In conclusion, nurses' compliance with PPE use is a multifactorial behavior shaped by the interaction of individual, organizational, and workplace factors. Improving compliance requires a comprehensive approach through continuous education, adequate PPE provision, strengthened safety culture, effective supervision, and organizational support to enhance healthcare worker safety and improve the quality of nursing care.]]>
