<![CDATA[Cervical cancer is one of the diseases caused by HPV virus infection. Cervical cancer ranks second as the leading cause of death in women in Indonesia. Based on WHO recommendations, HPV vaccine administration is the main prophylaxis to prevent cervical cancer which can be given from the age of 9 years. The effectiveness of the HPV vaccination program is influenced by one's knowledge and attitude. The purpose of this study was to determine the relationship between the level of knowledge and attitude of parents/guardians with the acceptance of the Human papillomavirus (HPV) vaccine in 5th grade elementary school students in Ambon City in 2024. This study used a correlation analytic design with a cross sectional approach. There were 112 respondents from ten grade 5 elementary schools selected by total sampling technique. Data were collected using a questionnaire research instrument of knowledge level, attitude, and acceptance of HPV vaccine. The data analysis technique used the Chi-square test. The results showed that the majority of respondents had a high level of knowledge (92.0%) with a high attitude (83.9%), and the majority accepted (50.9%). There was no relationship between knowledge and acceptance (p=0.015) with a value of r=0.105. There is no relationship between attitude and acceptance (p=0.734), with a value of r=0.735. So, it can be concluded that there is no significant relationship between the level of knowledge and attitude of parents/guardians with HPV vaccine acceptance.]]>
