<![CDATA[Background: Diabetes In-home smoking is a critical public health problem because it exposes household members, particularly children and pregnant women, to secondhand and thirdhand smoke. The proportion of "no household member smokes" indicator at Tanjung Agung Public Health Center, OKU Regency, remained far below the 80% target for three consecutive years (27% in 2023, 26% in 2024, 29% in 2025). Method: This study used a descriptive-analytic design with a cross-sectional approach. A total of 100 respondents aged ≥15 years were selected through systematic purposive sampling from 12 villages/sub-districts in the Tanjung Agung working area, using proportional allocation based on the Slovin formula. Data were collected through structured interviews and analyzed using univariate, bivariate (Chi-Square/Fisher's Exact), and multivariate (multiple logistic regression) analyses. Results: Of 100 respondents, 52% smoked inside the home. Bivariate analysis showed significant associations between sex (p=0.001), education (p=0.019), income (p=0.001), knowledge (p=0.001), and attitude (p=0.001) with in-home smoking behavior, while age showed no significant association (p=0.272). Multivariate analysis identified income (OR=20.407; 95% CI 3.306–125.980) as the dominant factor, followed by knowledge (OR=7.054; 95% CI 2.106–23.630). Conclusion: In-home smoking prevalence remains high, and low income combined with poor knowledge substantially increases the risk of this behavior. Health promotion targeting low-income households and strengthening smoke-free home policies are recommended. Keywords: In-home smoking, secondhand smoke, income, knowledge, PHBS]]>
