<![CDATA[According to the World Health Organization (WHO), diaper rash is relatively common worldwide and remains a prevalent health problem among infants and young children. International studies have reported 184,097 cases of diaper rash among children aged 0–3 years during the study period, with an average of 15,341 cases per year. A report from the Indonesian Ministry of Health in 2024 indicated that the prevalence of diaper rash among infants may reach approximately 50–65% during the diaper-use period. This high prevalence indicates that diaper rash remains a significant health concern and requires appropriate attention in primary healthcare services (Kilic et al., 2024). Diaper rash can be managed through non-pharmacological interventions, one of which is the use of aloe vera (Aloe vera). Aloe vera contains active compounds, including aloin, saponins, lignin, and vitamins A, C, and E, which contribute to accelerating wound healing and promoting skin tissue regeneration (Yanti et al., 2023). The aim of this study was to analyze the effect of aloe vera (Aloe vera) hydrogel application on diaper rash among infants aged 0–12 months. This study employed a pre-experimental design using a one-group pretest–posttest design to determine the effect of aloe vera hydrogel application on reducing the severity of diaper rash by comparing the condition before and after the intervention. The results showed a difference in the mean severity of diaper rash before and after the administration of aloe vera hydrogel. Statistical analysis demonstrated a p-value < 0.05, indicating a statistically significant difference in the mean severity of diaper rash before and after the administration of aloe vera hydrogel among infants aged 0–12 months at the Midwife Practice (BPM) in Bangun Sari Village, Asahan Regency. Therefore, aloe vera hydrogel can be considered a potential non-pharmacological intervention for reducing the severity of diaper rash in infants aged 0–12 months. Keywords: Aloe Vera Hydrogel, Diaper Rash, Infants]]>
