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Beyond the Anamnesis: Big Data Reveals Rash, Not Bleeding, as the Critical Predictor of Dengue Shock Syndrome Muhammad Almanfaluthi; Stefani Widodo; Arif Burhanuddin; Irma Putri Damayanti; Yusuf Adi Gunawan
Indonesian Journal of Innovation Science and Knowledge Vol. 3 No. 4 (2026): IJISK 2026
Publisher : Fakultas Pendidikan Ilmu Keguruan, Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/ijisk.v3i4.810

Abstract

Dengue shock syndrome (DSS) is a critical, life-threatening complication; however, early prediction remains highly challenging. Clinicians historically rely on classic warning signs obtained through subjective anamnesis, such as persistent fever and spontaneous bleeding, to triage patients despite the potential for observational bias. To address this clinical gap, this study aimed to evaluate the objective predictive value of isolated, patient-reported symptoms on the incidence of shock using a large-scale population dataset. A retrospective observational design utilized big data analytics on routine surveillance records from the Banyumas Regional Health Agency, spanning from 2024 to 2025. The analyzed dataset comprised 1,381 patients, and statistical models, including bivariate analyses and logistic regression, were constructed to quantify the association between individual clinical symptoms and shock outcomes. The findings reveal a striking clinical anomaly: classically feared symptoms, including bleeding and fever, lack significant predictive power for shock deterioration. Conversely, the presence of a rash emerges as a critical clinical indicator; patients presenting with a rash demonstrate a nearly twofold increased risk of progressing to shock (OR = 1.95). Relying exclusively on subjective anamnesis and universal symptom profiles proves unpredictable and insufficient for anticipating severe dengue. Therefore, a rash serves as a crucial early red flag for underlying plasma leakage, mandating healthcare providers to move beyond rigid textbook paradigms and adopt a holistic, adaptive diagnostic approach to optimize patient safety.
Defying Demographic Barriers: High Procedural Success of CTO-PCI in a Real-World Irma Putri Damayanti; Rahageng Wida Kusuma; Muhammad Almanfaluthi; Stefani Widodo; Yusuf Adi Gunawan
Indonesian Journal of Innovation Science and Knowledge Vol. 3 No. 4 (2026): IJISK 2026
Publisher : Fakultas Pendidikan Ilmu Keguruan, Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/ijisk.v3i4.811

Abstract

Chronic Total Occlusion (CTO) historically represented the "final frontier" in percutaneous coronary intervention, frequently resulting in surgical referral due to high failure rates. Procedural success was traditionally hypothesized to be limited by patient-specific demographic factors, such as advanced age and female gender, alongside the urgency of clinical presentation. To address this clinical gap, this study aimed to evaluate the real-world success rates of CTO interventions and determine whether these baseline demographic and clinical factors significantly predict procedural outcomes. A retrospective observational study was conducted using big data analytics on a catheterization logbook from a high-volume center, yielding a cohort of 187 patients who underwent CTO-PCI. Procedural outcomes, age, gender, and clinical status (emergency vs. elective) were evaluated using bivariate analysis and multivariable logistic regression. The findings reveal an exceptionally high overall procedural success rate of 93.0%. Statistical modeling demonstrates that advanced age, female gender, and emergency clinical status do not significantly predict procedural failure. Operator expertise and advanced crossing techniques effectively neutralize the anatomical complexities traditionally associated with adverse demographic profiles. In conclusion, CTO-PCI is highly safe and efficacious across diverse patient demographics; thus, patients must not be denied minimally invasive revascularization based on perceived, yet statistically unproven, demographic limitations.