Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Diponegoro Diponegoro International Medical Journal (DIMJ)
Mochtar, Arufiadi Anityo
Unknown Affiliation
Medicine & Pharmacology Neuroscience

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
KEJADIAN FISTULA UROGENITAL PADA PEREMPUAN DI RSUP DR. KARIADI SEMARANG Mukti, Ngesti Anggita; Mochtar, Arufiadi Anityo; Wiyati, Putri Sekar
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 1 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (389.12 KB) | DOI: 10.14710/dmj.v7i1.19378

Abstract

Latar Belakang: Fistula urogenital adalah hubungan abnormal antara saluran reproduksi wanita dan saluran kemih yang dapat mengakibatkan kebocoran urin. Fistula urogenital dapat menimbulkan dampak fisik maupun psikososial.Tujuan:Mengetahui angka kejadian serta karakteristik umum, faktor obstetri dan faktor ginekologi kejadian fistula urogenital pada perempuan di RSUP Dr. Kariadi Semarang.Metode: Penelitian deskriptif retrospektif. Data diambil dari data rekam medis pasien dengan fistula urogenital di RSUP Dr. Kariadi Semarang Periode Tahun 2013 – 2016. Analisis statistik dilakukan secara deskriptif dimana hasil penelitian disajikan dalam bentuk tabel distribusi dan frekuensi untuk setiap karakteristiknya.Hasil: Kejadian fistula urogenital pada perempuan di RSUP Dr. Kariadi Semarang selama periode 2013 – 2016 adalah sebanyak 36 kasus. Karakteristik umum pasien fistula urogenital, berdasarkan jenis fistula sebagian besar adalah fistula vesikovaginal ( 97,2%) dan sebagian besar terdiagnosis pada usia lebih dari 35 tahun (86,1 %). Status rujukan pasien terbanyak adalah bukan merupakan pasien rujukan (66,7%). Sebagian besar  pasien mengeluhkan munculnya keluhan inkontinensia urin adalah antara satu bulan sampai satu  tahun (50%).  Faktor ginekologi yang paling banyak menyebabkan fistula adalah operasi  histerektomi total (30,6%).Faktor obstetri terbanyak yang menyebabkan timbulnya fistula adalah persalinan dengan seksio sesarea (11,1%) dengan karakteristik maternal multipara, menikah pada usia diatas 18 tahun dan tingkat pendidikan terakhir yang ditempuh adalah SD.Kesimpulan: Kejadian fistula urogenital pada perempuan di RSUP Dr. Kariadi Semarang, sebagian besar disebabkan oleh faktor ginekologi, yaitu operasi histerektomi total.
The Effect of Moringa oleifera Extract on Histopathological of Mice Testes Exposed by Monosodium Glutamate Handoyo, Regenio Akira; Saraswati, Indah; Mochtar, Arufiadi Anityo; Armalina, Desy; Miranti, Ika Pawitra
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 6 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i6.37311

Abstract

Background: Monosodium glutamate (MSG) consumption in excess can have an impact on a man's fertility and lead to infertility. MSG has the potential to produce free radicals, which can harm cells. Antioxidants can fight off free radicals. Exogenous antioxidants are required to maintain equilibrium since there will be an imbalance if the body produces more free radicals than endogenous antioxidants. Exogenous antioxidants flavonoids are present in the leaves of the Moringa plant (Moringa oleifera L). It is thought that flavonoids have 4-5 times more antioxidant potential than vitamins. Objectives: To evaluate how moringa leaf extract affects the histopathological profile of MSG-exposed mouse testes. Methods: Only the posttest was used as a control group in this study. 25 male mice were used as the sample, and they were split up into five groups. The treatment group 1 (P1) received 6 g/day of MSG exposure + 300 mg/kg BW/day of moringa leaf extract, the treatment group 2 (P2) received 6 g/day of MSG exposure + 600 mg/kg BW/day of moringa leaf extract, and the treatment group 3 (P3) received 6 g/day of MSG exposure + 1200 mg/kg BW/day of moringa leaf extract. The control group (K-) received only standard feed. The mice were put to death after 30 days. The testes were removed for histological examination using hematoxylin-eosin staining, and the Johnsen scoring criteria were applied to their evaluation. Results: The data were not significant according to the Shapiro-Wilk test in the P3 group (MSG 6 g/day + Moringa Extract 1200 mg/kg BW/day). The Kruskal-Wallis test revealed that there was no significant difference between the seminiferous tubules according to the treatment group (p = 0.117). Conclusion: Moringa oleifera leaf extract protects the histopathological picture of the testes of male mice compared to the group given monosodium glutamate. 
Factors Associated With Recurrence Of Epithelial Ovarian Cancer In RSUP Dr. Kariadi Semarang Kurube, Isabela Marsialina; Ambari, Ediwibowo; Iskandar, Teuku Mirza; Tjahjanto, Hary; Dewantiningrum, Julian; Mochtar, Arufiadi Anityo; Trisetiyono, Yuli
Diponegoro International Medical Journal Vol 3, No 2 (2022): December 2022
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v3i2.15448

Abstract

Introductions: Epithelial ovarian cancer accounts for 90% of all ovarian malignancies. More than 70% of patients will experience a relapse even after receiving operative therapy and chemotherapy. There are several prognostic factors that influence the recurrence of ovarian cancer. In Indonesia, especially at Dr. Kariadi Hospital, Semarang, the data as mentioned above is still very limited.objective: Knowing the disease-free survival rate, optimizing surgery and factors related to the incidence of recurrence in epithelial ovarian cancer patients at Dr. Kariadi Hospital SemarangMethods: This study is a retrospective cohort study with survival analysis. Data were collected through medical records, with the study population are patients with a diagnosis of epithelial ovarian cancer who were treated at Dr. Kariadi Hospital Semarang in period January 2018-December 2019. Furthermore, patients who had been remission were observed for signs of disease recurrence for 2 years period.Results: There were 361 patients with epithelial ovarian cancer who underwent primary treatment at Dr. Kariadi Hospital, Semarang in  2018-2019. Furthermore, there were observations of recurrence in 148 patients who achieved remission. Of these 76 patients (51.4%) experienced recurrence, while 72 patients not relapse. From 148 epithelial ovarian cancer patients who underwent cytoreduction surgery at Dr. Kariadi Hospital, Semarang, 113 patients (76.4%) achieved optimal operation with a residu less than 2 cm, while 35 patients (23.6%) were not optimal with a residu more than 2 cm. FIGO stage (HR 2.44) and tumor residu (HR 2.15) were shown to be significant factors associated with the recurrence of epithelial ovarian cancer.Conclusion: Overall disease-free survival in epithelial ovarian cancer at Dr. Kariadi Semarang were 74.8% (6 months), 57.1% (1 year), 42.5% (18 months), and 37.4% (2 years). Tumor residual factors and FIGO stage were shown to be significant prognostic factors influencing the recurrence of epithelial ovarian cancer. 
Co-Authors Desy Armalina Ediwibowo Ambari Handoyo, Regenio Akira Hary Tjahjanto Ika Pawitra Miranti Indah Saraswati Julian Dewantiningrum Kurube, Isabela Marsialina Mukti, Ngesti Anggita Putri Sekar Wiyati Teuku Mirza Iskandar, Teuku Mirza Yuli Trisetiyono, Yuli