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All Journal Jurnal Kedokteran Diponegoro Medica Hospitalia

Wikanta, Edmond Rukmana

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Author-ID : 1148984

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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THE INFLUENCE OF CHEESE CONSUMPTION ON THE DEGREE OF ACNE VULGARIS IN STUDENTS OF MEDICINE FACULTY OF DIPONEGORO UNIVERSITY Koncara, Fatan Khalif; Wibowo, Dhega Anindita; Riyanto, Puguh; Wikanta, Edmond Rukmana
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 2 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Introduction : Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles with a polymorphic clinical picture consisting of various skin disorders in the form of blackheads, papules, pustules, nodules, and scar tissue. Four pathogenesis underlying the emergence of AV include polysebaseal follicle hyperproliferation, excess sebum production, inflammation, and the presence of Propionibacterium acnes. The cause of this multifactorial AV, one of which is a factor of consuming fatty foods, especially saturated fat, one of the foods is cheese. Cheese is one of the foods that we usually consume as processed foods that contain lots of saturated fat. Consuming fatty foods on an irregular basis can cause acne vulgaris. Objectives : To determine the relationship of fatty food consumption with the severity of acne vulgaris in Diponegoro University Kedokeran Faculty studentsMethods : This study uses a descriptive observational design with cross sectional design in which the researcher will describe how the incidence of acne vulgaris, the severity of acne vulgaris and the factors that influence acne vulgaris, especially regarding saturated fat consumption in excess cheese in Diponegoro University Medical School students. Samples were taken by purposive sampling to produce 40 students who met the inclusion and exclusion criteria. Assessment is assessed by filling out questionnaires suffering from acne vulgaris and assessing acne vulgaris in respondents. Analysis of the data used in the study is an analysis with the Chi Square test. Result : In conclusion, clustered pimples are a dominant factor in the assessment of acne (p<0,05). Conclusion: In this study it was found that there was no significant relationship between cheese consumption with the severity of acne vulgaris and pimples arising from acne is acne that occurred before the existence of this studyKeywords : acne vulgaris, fat, cheese

THE EFFECT OF JENGKOL SEED (Archidendron pauciflorum) EXTRACT TO PLASMA MDA LEVEL DUE TO DEEP SECOND DEGREE BURN WOUND IN SPRAGUE DAWLEY RATS Kurniati, Steffi; Batubara, Lusiana; Wikanta, Edmond Rukmana; Johan, Andrew
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Background: During inflammatory phase of the burn healing process, the number of plasma MDA levels tend to increase, which may cause damage towards cells and thus delay the resolution of burn wounds. Some research has been done in order to find alternative treatment for burn wound, including the application of antioxidant. Jengkol contains many antioxidant compounds which are expected to reduce plasma MDA levels, so it can accelerate the healing of burn wound. Aim: To prove that administration of jengkol extract can reduce plasma MDA level in Sprague dawley rats which were been given burn wound. Method: This experiment was using pre and post-test control group design, with 20 Sprague dawley rats as samples. All of the samples were given deep second degree burn wound which were then divided equally into 2 groups, treatment group (given jengkol extract 500 mg/KgBW) and control group (not given anything). Plasma MDA levels were then analyzed by using TBARS method. Data was analyzed using paired T-test, Wilcoxon, Mann-Whitney, and independence T-test. Result: There is no significant difference between the mean of plasma MDA levels in pre and post-test of either control group (p=0.771) or in the treatment group (p=1.00). Using Mann-Whitney test, there isn’t any significant difference in the pre-test between control and treatment group (p=0.677) or in the post-test between control and treatment group (p=0.916) by using independence T-test. Conclusion: Jengkol extract cannot reduce plasma MDA levels of Sprague dawley rats which were given burn wound.

PERBEDAAN RIWAYAT PENYAKIT TIROID TERDAHULU, METASTASIS DAN ABNORMALITAS PEMERIKSAAN ULTRASONOGRAFI ANTARA PASIEN KARSINOMA TIROID PAPILER KLASIK DAN VARIAN FOLIKULER DI RSUP Dr. KARIADI SEMARANG Firdauzi Putri, Nabila Zenska; Istiadi, Hermawan; Wikanta, Edmond Rukmana; Miranti, Ika Pawitra
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 1 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Background: Papillary thyroid carcinoma (PTC) is the most common carcinoma, accounting for more than 90% of all malignancies, where the most variants are classic papillary thyroid carcinoma and follicular variant papillary thyroid carcinoma (PTCVF). The characteristics of previous thyroid disease history, regional metastases, and ultrasound examination results can influence the clinical examination between the two variants of PTC, namely classic PTC and PTCVF. Aim: Understanding the differences in the history of previous thyroid disease, metastases, and ultrasound examination abnormalities between Classical Papillary Carcinoma and Follicular variants at Dr. Kariadi Hospital, Semarang. Methods: A cross sectional study with consecutive sampling method in classic PTC and PTCVF patients in Dr. Kariadi Hospital, Semarang who was diagnosed in the period January to June 2019. In this study, the number of samples obtained was 18 medical records with classic PTC cases and 20 medical records with PTCVF cases. The dependent variables, namely history of previous thyroid disease, regional metastases, and ultrasound examination abnormalities, all of which were on an ordinal scale, were analyzed using non-parametric chi-square test and Fisher's Exact test. Results: In the non-parametric chi-square test and Fisher's Exact test, the results were not significant (p = 0.474), regional metastases were not significant (p = 0.359), ultrasound size abnormalities were not significant (p = 0.323), and abnormalities. ultrasound nodal was not significant (p = 0.595). Conclusion: There was no statistically significant difference in the history of previous thyroid disease, regional metastases, and ultrasound examination abnormalities between classic PTC and PTCVF patients at Dr. Kariadi Hospital, Semarang.

PERBEDAAN USIA, UKURAN MAKROSKOPIS TUMOR, DAN PROFIL HORMON ANTARA PASIEN KARSINOMA TIROID PAPILER KLASIK DAN VARIAN FOLIKULER DI RSUP DR KARIADI SEMARANG Nabila, Alin; Istiadi, Hermawan; Wikanta, Edmond Rukmana; Miranti, Ika Pawitra; Puspasari, Dik
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 2 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Background: New cases of Papillary Thyroid Carcinoma and Carcinoma patients at Dr. Kariadi Hospital, Semarang is quite high, where the most types are Classical Papillary Thyroid Carcinoma and Follicular Variant Papillary Thyroid Carcinoma. On the other hand, in diagnosing PTC, histopathological examination which is a gold standard sometimes has a subjective value. Therefore, it is necessary to have a correlation with the clinical characteristics of the patient in order to get a correct diagnosis. Aim: Understanding the differences in age characteristics, tumor macroscopic size and hormone profile between Classical Papillary Thyroid Carcinoma and Follicular Variant patients at Dr. Kariadi Hospital, Semarang. Method: Analytic observational research with cross sectional design. The number of samples was 38 medical records in which 18 cases of Classic Papillary Thyroid Carcinoma and 20 cases of Follicular Variant Papillary Thyroid Carcinoma. Data with a nominal scale, namely age were analyzed using the Fisher exact test, while the data with a numerical scale, namely the macroscopic size of the tumor and the hormone profile, were tested for normality of Saphiro Wilk then continued with the Mann-Whitney test. Result: Based on the Fisher exact test, there was significant difference (p = 0,009) between age characteristics and Classical Papillary Thyroid Carcinoma and Follicular Variant. In the Mann-Whitney test there was no significant difference (p = 0.3) between the macroscopic size of the classical papillary carcinoma and follicular variant and there was no significant difference TSHs (p = 0.501) and fT4 (p = 0.953) hormone profiles between Classic Papillary Thyroid Carcinoma and Follicular Variants. Conclusion: There was significant difference between the characteristics of age at diagnosis, and there was no significant difference between the macroscopic size of the tumor and the hormonal profile of Classical Papillary Carcinoma and Follicular Variants in Dr. Kariadi Hospital, Semarang.

Co-Authors Andrew Johan Dhega Anindita Wibowo, Dhega Anindita Dik Puspasari, Dik Firdauzi Putri, Nabila Zenska Hermawan Istiadi Ika Pawitra Miranti Koncara, Fatan Khalif Kurniati, Steffi Lusiana Batubara Nabila, Alin Puguh Riyanto

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