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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran Diponegoro
Dhega Anindita Wibowo, Dhega Anindita
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Health Professions Medicine & Pharmacology

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THE INFLUENCE OF CHEESE CONSUMPTION ON THE DEGREE OF ACNE VULGARIS IN STUDENTS OF MEDICINE FACULTY OF DIPONEGORO UNIVERSITY Koncara, Fatan Khalif; Wibowo, Dhega Anindita; Riyanto, Puguh; Wikanta, Edmond Rukmana
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 2 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.253 KB) | DOI: 10.14710/dmj.v9i2.27076

Abstract

Introduction : Acne vulgaris is a chronic inflammatory disease of pilosebaceous follicles with a polymorphic clinical picture consisting of various skin disorders in the form of blackheads, papules, pustules, nodules, and scar tissue. Four pathogenesis underlying the emergence of AV include polysebaseal follicle hyperproliferation, excess sebum production, inflammation, and the presence of Propionibacterium acnes. The cause of this multifactorial AV, one of which is a factor of consuming fatty foods, especially saturated fat, one of the foods is cheese. Cheese is one of the foods that we usually consume as processed foods that contain lots of saturated fat. Consuming fatty foods on an irregular basis can cause acne vulgaris. Objectives : To determine the relationship of fatty food consumption with the severity of acne vulgaris in Diponegoro University Kedokeran Faculty studentsMethods : This study uses a descriptive observational design with cross sectional design in which the researcher will describe how the incidence of acne vulgaris, the severity of acne vulgaris and the factors that influence acne vulgaris, especially regarding saturated fat consumption in excess cheese in Diponegoro University Medical School students. Samples were taken by purposive sampling to produce 40 students who met the inclusion and exclusion criteria. Assessment is assessed by filling out questionnaires suffering from acne vulgaris and assessing acne vulgaris in respondents. Analysis of the data used in the study is an analysis with the Chi Square test. Result : In conclusion, clustered pimples are a dominant factor in the assessment of acne (p<0,05). Conclusion: In this study it was found that there was no significant relationship between cheese consumption with the severity of acne vulgaris and pimples arising from acne is acne that occurred before the existence of this studyKeywords : acne vulgaris, fat, cheese
The Effect of Coffee on Spermatozoa Motility and Morphology of BALB/c Mice Exposed to Electric Mosquito Repellent Mulyono, Yehezkiel Andrew; Prihasna, Septika Nuri; Wibowo, Dhega Anindita; Johan, Andrew; Ngestiningsih, Dwi; Juniarto, Achmad Zulfa
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 12, No 1 (2021): June 2021
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (946.485 KB) | DOI: 10.30659/sainsmed.v12i1.12580

Abstract

Introduction: Electric mosquito repellent which contains d-allethrin producing free radicals, affects the quality of sperm motility and morphology. Antioxidants contained in coffee can counteract the free radicals in the body. Objective: To evaluate the effect of coffee on sperm motility and morphology of BALB/c mice exposed to electric mosquito repellent. Methods: In this experimental study was conducted with post-test only control group design, 24 BALB/c mice randomized into 4 groups. The negative control group was a group without treatment. The positive control group was exposed to electric mosquito repellent. Group P1 and P2 were exposed to electric mosquito and given the coffee solutions with the doses respectively 52 mg/0.5 mL and 78 mg/0.5 mL. The treatment was given for 35 days. On the 36th day, all mice were terminated and their sperm motility and morphology were examined. The data were then analyzed with the non-parametric test of Kruskal-Wallis. Differences were considered significant when the value of p<0.05 with confidence interval 95%.Results: The result of pairwise comparison test progressive sperm motility shows that there was a significant difference between positive control group with P2 group (p=0.006), positive control group with negative control group (p<0.001), and P1 group with negative control group (p=0.004). The result of Kruskal-Wallis test for sperm morphology shows that there was no significant difference between those four groups (p=0.885).Conclusion: Coffee can significantly increase the sperm motility but didn’t significantly increase the normal sperm morphology percentage of BALB/c mice exposed by electric mosquito repellent.
The Effect of Moringa Leaves Extracts on MDA Level in Male Mice Exposed to Electromagnetic Radiation of Mobile Phones Amalia, Nadia Ilmi; Budisulistyo, Trianggoro; Wibowo, Dhega Anindita; Sareharto, Tun Paksi
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 4 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i4.43905

Abstract

Background: The use of cell phones causes anxiety about the effects of electromagnetic wave radiation emitted because of the production of free radicals in the body is increased by cell phone electromagnetic wave radiation. This escalation results in an elevated production of Reactive Oxygen Species (ROS), resulting in elevated Malondialdehyde (MDA) levels due to lipid peroxidation, which is toxic to the body. One way to reduce MDA levels is to introduce antioxidants into the body. Previous studies have found that Moringa leaf extract can be used as a good source of antioxidants.Objective: The aim of this research was to assess the impact of Moringa leaf extract administration on the MDA levels in BALB/C mice subjected to electromagnetic waves emitted by cell phones.Methods: This study employed an experimental study with a post-test only control group design. The research involved 23 male BALB/c mice, divided into four groups. The healthy control group received no treatment, while the negative control group was exposed to cell phone electromagnetic waves for 2 hours/day. Groups P1 and P2 received Moringa leaf extract at doses of 100 mg/kgBW and 400 mg/kgBW, respectively, in addition to being exposed to cellular phone electromagnetic waves for 2 hours/day. The treatment was administered for 30 days following a 7-dayadaptation period. On the 31st day, blood plasma samples were takenfrom all mice and examined for MDA levels. The data underwent analysis through non-parametric One-Way ANOVA and subsequent Pos Hoc LSD tests. Significance is acknowledged for p-values less than 0.05.Results: The highest MDA levels were found in the K (-) group, namely 0.43 ± 0.18 ppm, and the lowest MDA levels were observed in the P1 group, with values of 0.19 ± 0.08 ppm. A significant difference was noted between the K (-) group and the P1 group (p = 0.05), while no significant difference were observed in the other groups.Conclusion: Administering Moringa leaf extract at a dose of 100 mg/kgBW/day can reduce MDA levels in mice exposed to electromagnetic waves from cell phones.
Co-Authors Achmad Zulfa Juniarto Amalia, Nadia Ilmi Andrew Johan Budisulistyo, Trianggoro Djuara P Lubis Koncara, Fatan Khalif Mulyono, Yehezkiel Andrew Prihasna, Septika Nuri Puguh Riyanto Tun Paksi Sareharto Wikanta, Edmond Rukmana