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All Journal Acta Pharmaciae Indonesia : Acta Pharm Indo JURNAL PENDIDIKAN TAMBUSAI CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Jurnal Sains dan Kesehatan
Pratama, Anggara Martha
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Cost-effectiveness analysis of lopinavir, ritonavir, and nevirapine toward HIV AIDS patients as antiretroviral: a systematic review Pratama, Anggara Martha; Pramestutie, Hananditia Rachma; Krisnadewi, Kadek Ida; Pratiwi, Hening
Acta Pharmaciae Indonesia Vol 11 No 2 (2023): Acta Pharmaciae Indonesia: Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2023.11.2.6916

Abstract

Background: The mobilization of resources to prevent and treat human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) is unparalleled in the history of public health. Nevirapine resistance may decrease the effectiveness of viral suppression with nevirapine-based HIV in women infected with human immunodeficiency virus (HIV) with previous exposure to single-dose nevirapine. However, the alternative lopinavir/ritonavir–based antiretroviral therapy (ART) regimen is more expensive. Objective: Our objectives were to project the tradeoffs regarding the cost-effectiveness of ART regimens for nevirapine-exposed and lopinavir/ritonavir. Methods: A thorough literature search was conducted using PubMed and SAGE databases, employing search terms such as “cost-effectiveness analysis,” AND “HIV AIDS,” AND “lopinavir,” OR “ritonavir,” AND “nevirapine.” Additionally, hand searches were carried out on Google Scholar with various combinations of these terms to ensure comprehensive coverage of relevant studies. Results: Six studies met the our inclusion criteria and were reviewed. The analysis confirms that both nevirapine and lopinavir/ritonavir-based ART regimens are cost effective in a range of settings, despite differences in their relative efficacy and contexts in which they are used. Conclusion: This systematic review collates recent studies on the cost-effectiveness of nevirapine and lopinavir/ritonavir in ART. It showed that in this finding, there are cost effective but this article had wide variation with comparison therapy. Cost-effectiveness results depended on the relative efficacy of lopinavir/ritonavir and nevirapine in both first-line and second-line ART.
Formulasi Hand and Body Lotion Antioksidan Kombinasi Ekstrak Daun Lengkeng (Dimocarpus Longan) dan Kulit Jeruk Lemon (Citrus Limon) Pratama, Anggara Martha; Trisnawati, Elita Devi
Jurnal Pendidikan Tambusai Vol. 7 No. 3 (2023): Desember 2023
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jptam.v7i3.11570

Abstract

Daun Lengkeng mengandung senyawa flavonoid. Kandungan senyawa lain yang terdapat dalam daun Lengkeng yaitu saponin, tanin, dan hidrokuinon. Buah lemon merupakan tanaman yang memiliki manfaat sebagai antioksidan alami. Kulit jeruk lemon sering dikeringkan menjadi bahan obat-obatan Penelitian ini bertujuan untuk mengetahui untuk mengetahui kombinasi ekstrak kulit jeruk lemon (citrus lemon) dan daun lengkeng (Dimocarpus Longan) dapat dijadikan sebagai sediaan hand and body lotion dan mengetahui khasiat antioksidan yang terdapat dalam ekstrak kulit jeruk lemon (citrus lemon) dan daun lengkeng (Dimocarpus Longan). Dilakukan ekstraksi pada daun lengkeng dan kulit jeruk lemon dengan metode maserasi. Uji antioksidan ini dilakukan dengan menggunakan metode DPPH. Kombinasi daun lengkeng dan kulit jeruk lemon mengandung banyak antioksidan yang cocok untuk dijadikan sediaan hand body lotion. Hasil ekstraksi daun lengkeng dan kulit jeruk lemon mempunyai aktivitas antioksidan dan dapat dibuat sediaan hand and body lotion dengan menunjukan pH 5. Hasil analisis data dengan menggunakan uji parametrik one way anova menunjukan bahwa kulit jeruk lemon dan daun lengkeng bisa dijadikan formulasi hand and body lotion, dengan uji Shapiro wilk menunjukan normalitas dan homogen.
Pengetahuan Dan Sikap Tentang Berhenti Merokok Pada Perokok Aktif Di Kelurahan Ketintang Surabaya: Mix-Method Putri, Putu Melista; Pratama, Anggara Martha; Juwariya, Firdayatul; Raharjo, Dian Natasya; Lorensia, Amelia
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 3 No. 3 (2023): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v3i3.124

Abstract

The prevalence of smoking in adolescents has increased from year to year. Smoker awareness is very important inincreasing the success of quitting smoking. The level of knowledge and attitudes is needed for self-managementattitudes for smokers. The aim of this study was to determine the level of knowledge and attitudes about smokingcessation among active smokers in the Ketintang Village, Surabaya. The design that will be used in this study isMix-Methods with Convergent Parallel Design. This research was conducted in Ketintang, Surabaya, with theconsideration of the availability of active smokers in a Mosque Youth and Youth Organization organization, whichwas carried out for 2 months starting April 2022 - June 2022. The variables measured in this study included thelevel of knowledge and attitudes of active smokers about quitting smoking. Data collection was carried out by indepth interviews and data were analyzed descriptively. Respondents involved in the study were 40 people. Theaverage respondent has good knowledge (90.00%) and a positive attitude (95.00%). Respondents thought that thetypes of cigarettes according to respondents were ordinary cigarettes (conventional), shisya, and vape. Respondentsthought that the way to quit smoking could be done by making an independent effort to quit, avoiding smokers'surroundings, and replacing conventional cigarettes with electric cigarettes (vape). Therefore, smoking cessationprograms need to be improved, especially for smokers who wish to quit smoking.
Pharmaceutical Care for Smoking Cessation: A Pilot Study on Understanding Knowledge and Experience Through a Mixed-Methods Approach Lorensia, Amelia; Pratama, Anggara Martha; Wardani, Mariani Ika; Suryadinata, Rivan Virlando; Raharjo, Dian Natasya; Budipramana, Krisyanti
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2249

Abstract

Smoking is one of the biggest threats to public health in the world, so pharmacists should have a role in a multidisciplinary team to provide pharmaceutical care in smoking cessation in pharmacy. The research purpose was to determine the level of knowledge and experience of pharmacist pharmacy services on smoking cessation programs at pharmacists in East Surabaya. This research was mixed-method research, using the explanatory sequential design strategy. Data collection was carried out from October 2021 to January 2022 in Surabaya, East Java, Indonesia. The research variable were knowledge and experience related to pharmaceutical care in smoking cessation. The sample were pharmacists who carried out clinical pharmacy services at pharmacies in East Surabaya. Respondents were interviewed in depth until the data reached the saturation level (saturation so that no new answers/explanations are found) in order to obtain good and usable qualitative data. This study involved 40 respondents. Most of the respondents had sufficient knowledge level (57.50%). Many participants attended seminars on smoking cessation (55%), but none of the respondents had experience in pharmaceutical services. Some respondents have experience in giving advice on smoking cessation to patients during drug delivery at pharmacies (62.50%). Most of the respondents knew dangers of smoking and its relation to health, but most of them cannot explain the theoretical mechanism of the disease pathophysiologically. Pharmacists in pharmacies had sufficient knowledge about smoking cessation, but the practice of pharmaceutical services was still lacking. This could be due to the need to improve information regarding smoking cessation regulations for health workers. Keywords:          experience, knowledge, pharmacist, smoking scessation
Co-Authors Amelia Lorensia Budipramana, Krisyanti Hening Pratiwi, Hening Juwariya, Firdayatul Krisnadewi, Kadek Ida pramestutie, hananditia rachma Putu Melista Putri Raharjo, Dian Natasya Suryadinata, Rivan Virlando Trisnawati, Elita Devi Wardani, Mariani Ika