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All Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Fatma Dwi Nurjanah
Universitas Duta Bangsa Surakarta
Health Professions Nursing Public Health

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Formulasi dan Uji Efektivitas Antijamur Sediaan Hair Tonic Ekstrak Daun Kersen (Mutingia Calabura L.) terhadap Malassezia Furfur sebagai Antiketombe Secara In Vitro Fatma Dwi Nurjanah; Tatiana Siska Wardani; Anita Dwi Septiarini
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 6 (2026): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i6.2594

Abstract

Dandruff (Pityriasis Sicca) is one of the most common skin disorders. It is characterized by peeling of the epidermis of the scalp in gray or white color accompanied by itching. The prevalence of dandruff worldwide reaches 50% and in Indonesia it reaches 26%. This study aims to see the antifungal activity of hair tonic preparations of cherry leaf extract against the fungus Malassezia Furfur which causes dandruff by observing the resulting inhibition zone. This study used an experimental laboratory method. Cherry leaf extract was obtained from the maceration of simplicia using 96% ethanol. The results of phytochemical screening showed positive results for flavonoids, saponins, tannins, and steroids. The hair tonic formulation was subjected to physical quality tests including organoleptic tests, homogeneity, viscosity, pH, hedonic and irritation. The antifungal test used the disc diffusion technique (Kirby-Bauer) with 3 different concentrations of FI 30%, FII 40%, FIII 50%. The results of the inhibition zone test were 6.23mm, 8.01mm, and 8.22mm, respectively, which can be concluded that the higher the extract concentration, the larger the inhibition zone produced. Statistical testing used One Way ANOVA followed by the Kruskal Walis non-parametric test.
Co-Authors Anita Dwi Septiarini Tatiana Siska Wardani