Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Dentika Dental Journal
Aimee Monica
Unknown Affiliation
Dentistry

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
PENGARUH PEMBERIAN KOMBINASI SEL PUNCA PULPA GIGI DAN RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2 TERHADAP KADAR FOSFATASE ALKALI PADA PULPA GIGI TIKUS TERINFLAMASI: COMBINATION OF RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN- 2 AND DENTAL PULP STEM CELLS ENHANCED EXPESSION OF ALKALINE PHOSPHATASE ON INFLAMED RAT’S PULP Endang W Bachtiar; Mindya Yuniastuty; Aimee Monica; Boy M Bachtiar
Dentika: Dental Journal Vol. 16 No. 1 (2011): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.545 KB) | DOI: 10.32734/dentika.v16i1.1897

Abstract

Pulp irritation will form reparative dentin as a defense mechanism. Currently, the materials used to help the defense pulp still have many shortcomings. Therefore, the effect of dental pulp stem cells (DPSC) and rhBMP- 2 combination on alkaline phosphatase (ALP) expresion in rat ’s dental pulp was analyzed in this research. Lipopolysaccharide was used to irritate the pulp of 12 Sprague-Dawley rats. Materials were then applied to each group and ALP expression was performed on the first and second week. The result showed that in the first week, giving a combination of pulp stem cells with recombinant BMP-2 had not been visible to increase expression of alkaline phosphatase (ALP), a biomarker regeneration of pulp, but the increase in ALP expression occurred in the second week. In conclusion, a combination of pulp stem cells and rhBMP-2 can increase the expression of ALP on inflamed rat’s pulp.
Co-Authors Boy M Bachtiar Endang W Bachtiar Mindya Yuniastuty