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PENGARUH EKSTRAK ETANOL DAUN GAMBIR (UNCARIA GAMBIR) DIBANDINGKAN DENGAN CHLORHEXIDINE GLUCONATE 0,2% TOPIKAL TERHADAP PENYEMBUHAN LUKA MUKOSA PALATUM TIKUS GALUR WISTAR: EFFECT OF ETHANOL GAMBIR LEAVES (UNCARIA GAMBIR) COMPARED WITH CHLORHEXIDINE GLUCONATE 0,2% TOPICAL FOR WOUND HEALING ON PALATE MUCOSAL GALUR WISTAR RAT Dita Septiani; Euis Reni Yuslianti; Saskia Lenggogeni Nasroen
Dentika: Dental Journal Vol. 18 No. 3 (2015): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (626.945 KB) | DOI: 10.32734/dentika.v18i3.1973

Abstract

Gambir (Uncaria gambir) digunakan masyarakat secara empiris dalam membantu penyembuhan luka karena memilikikemampuan antibakteri, antiinflamasi dan antioksidan. Penelitian ini bertujuan mengetahui pengaruh ekstrak etanol daungambir topikal terhadap penyembuhan luka mukosa palatum tikus galur wistar dibandingkan chlorhexidine gluconate0,2% ditinjau dari luas permukaan luka dan lama penyembuhan luka serta mengetahui dosis efektif ekstrak etanol daungambir secara topikal untuk penyembuhan luka optimal. Metode penelitian menggunakan rancangan penelitianeksperimental murni laboratoris bersifat analitik. Tikus dibagi acak menjadi tujuh kelompok yaitu kelompok kontrolnegatif, kelompok chlorexidine gluconate 0,2%, kelompok ekstrak etanol daun gambir dosis 1,75 mg, 3,5 mg, 7 mg, 14mg dan 28 mg. Luka diamati hari ke-0, 3, 7 dan 14. Hasil penelitian menunjukkan ekstrak etanol daun gambirberpengaruh terhadap penyembuhan luka berhubungan dengan kandungan daun gambir yaitu katekin, asamcathechutannat, quersetin, tanin, alkaloid, saponin dan gambiriin berperan sebagai antibakteri, antiinflamasi danantioksidan. Hasil tes statistik luas permukaan luka dengan uji Kruskal-Wallis menunjukkan nilai p=0,00 dan hasil tesstatistik efektivitas dosis dengan uji Friedman menunjukkan nilai p=0,00. Sebagai kesimpulan, ekstrak etanol daungambir dapat lebih cepat memperkecil luas dan lama penyembuhan luka dibandingkan chlorhexidine gluconate 0,2%serta didapatkan dosis efektif yaitu 28 mg.
Planning the Implementation of a 3R (Reduce, Reuse, and Recycle) Waste Management Facility for the Prevention of Waste-Related Diseases in Sukawening Village, Bandung Regency Allan Darma Putra Pramudita; Melbi Tanjung; Sri Ratna Wulan; Muhammad Anang Hadiat; Riska Septiana; Dita Septiani
Society : Jurnal Pengabdian Masyarakat Vol. 5 No. 3 (2026): Mei
Publisher : Edumedia Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55824/ntf0an28

Abstract

Waste generation in Sukawening Village has exceeded the capacity of the existing 3R (Reduce, Reuse, and Recycle) temporary waste management facility (TPS 3R), while current waste treatment practices still rely on open burning. Therefore, it is necessary to develop a plan for a TPS 3R facility capable of accommodating all household waste and reducing waste generation without the use of burning in Sukawening Village.The community service methodology employed in this study includes educational seminars on waste management, the promotion of a healthy environmental culture, and practical training on household-scale composting. In addition, a quantitative approach was applied to develop a feasible TPS 3R planning framework for Sukawening Village. The outcomes of this community service activity are expected to promote more environmentally friendly behavior among the community, enable households to reduce waste generation through composting practices, and provide a viable plan for the development of a TPS 3R facility in Sukawening Village.