This study aims to examine the process of making a biopesticide treatment based on six main ingredients developed at PT. Taman Indah Lestari (Taman Simalem Resort). This biopesticide is studied as a pest control in an organic farming system and supports the concept of Integrated Pest Management (IPM). The research method is carried out through the extraction process of natural ingredients including rhizomes (turmeric, galangal, ginger), gambier, soursop leaves, spoon leaves, senduduk leaves, and BPCS formulation (bamboo soil, bitter leaf, eucalyptus, and lemongrass) using a water solvent with a ratio of 1:10 and a soaking time of 12–24 hours. The ingredients used contain secondary metabolites such as flavonoids, alkaloids, tannins, saponins, and essential oils that act as antimicrobials, insecticides, repellents, and antifeedants. The mechanism of action of the biopesticide includes disruption of microbial cell membranes, inhibition of insect metabolism and enzymes, and disruption of the nervous and respiratory systems of pests. The combination of ingredients provides a synergistic effect that is able to kill pests, thereby suppressing pest populations gradually and sustainably. Thus, this natural-based biopesticide treatment has the potential to be an effective and sustainable solution for pest control without causing negative impacts on the environment or human health.