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Correlation between Diffuse Hepatic Steatosis Severity and Hemoglobin Levels on Non-Contrast Abdominal CT Vincent Viandy; Evo Elidar Harahap; M. Aron Pase; Putri Chairani Eyanoer
Indonesian Journal of Global Health Research Vol. 8 No. 6 (2026): Indonesian Journal of Global Health Research: December 2026
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i6.2869

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common chronic liver disease, and hemoglobin has been reported to be associated with hepatic steatosis. This study evaluated the correlation between the degree of diffuse hepatic steatosis assessed by non-contrast computed tomography (NCCT) and hemoglobin levels. This observational analytic cross-sectional study included 81 patients who underwent non-contrast abdominal CT at Adam Malik Hospital. Hepatic attenuation was measured using three 100-mm² regions of interest in the posterior right lobe, anterior right lobe, and left lobe. Diffuse hepatic steatosis was categorized as mild (41.4–48.9 HU), moderate (36.4–41.4 HU), or severe (21.4–36.4 HU). Hemoglobin was categorized into quartiles. Associations with hemoglobin, body mass index (BMI), diabetes mellitus, and sex were analyzed using Pearson chi-square tests. Inter-reader agreement was assessed using Cohen’s kappa. The median age was 51 years. Women comprised 54.3% of participants, and the median BMI was 25.71 kg/m². Severe diffuse hepatic steatosis was present in 64 participants (79.0%), mild in 9 (11.1%), and moderate in 8 (9.9%). Mean hemoglobin was 12.9 ± 2.2 g/dL. Inter-reader agreement for hepatic steatosis grading was very good (κ=0.837). No significant association was found between hepatic steatosis grade and hemoglobin quartile (p=0.422), diabetes mellitus (p=0.077), or sex (p=0.965). BMI was significantly associated with hepatic steatosis grade (p=0.011). In this study population, the degree of diffuse hepatic steatosis on NCCT was not significantly associated with hemoglobin level. BMI showed a significant association with hepatic steatosis severity.
The Correlation Between Visceral Fat Levels and Fasting Blood Glucose in Type 2 Diabetes Patients at Primary Health Facility in Medan Aisy Putri; Dina Keumala Sari; Fitriyani Nasution; Santi Syafril; M. Aron Pase; Jennifer Setiawan
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 8 No. 1 (2026): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v8i1.24782

Abstract

Introduction: Type 2 diabetes mellitus (T2DM) is a major metabolic disorder closely linked to visceral adiposity and insulin resistance. Visceral fat is metabolically active and contributes to inflammation and impaired glucose regulation. Evidence regarding the association between visceral fat and fasting blood glucose in primary healthcare populations remains limited. This study aimed to examine the correlation between visceral fat levels and fasting blood glucose among patients with T2DM in a primary care setting. Methods: This cross-sectional analytic study was conducted at a primary healthcare facility in Medan between October and December 2025. Sixty adult patients with confirmed T2DM were recruited using consecutive sampling. Visceral fat levels were measured using bioelectrical impedance analysis, and fasting blood glucose was assessed after an overnight fast using standardized laboratory methods. Sociodemographic and clinical variables were recorded. Data distribution was tested using the Kolmogorov–Smirnov test, and correlation analysis was performed using Spearman’s rho with a significance level of p<0.05. Results: Participants had a median age of 63.5 years, and 61.7% were female. The median body mass index was 25.4 kg/m² and median fasting blood glucose was 154 mg/dL. Both visceral fat and fasting glucose were non-normally distributed (p<0.001). Correlation analysis demonstrated a weak positive association between visceral fat and fasting blood glucose (r=0.173), which was not statistically significant (p=0.186). Discussion: The findings suggest that fasting glycemic status in established T2DM is influenced by multifactorial mechanisms beyond adiposity alone, including treatment effects and disease progression. Conclusion: Although non-significant, the positive trend supports the metabolic relevance of visceral adiposity. Assessment of visceral fat remains important for cardiometabolic risk evaluation in primary care. Keywords: Diabetes Mellitus, Type 2; Visceral Fat; Blood Glucose; Obesity, Abdominal