Nugroho, Lathifa Zahra Putri
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Intermittent Fasting and Cardiometabolic Health in Adults with Obesity: A Scoping Review Siswati, Tri; Nugroho, Lathifa Zahra Putri; Gina, Natasya Nurul; Sitasari, Almira; Wijanarka, Agus
Indonesian Journal of Public Health Nutrition (IJPHN) Vol. 5, No. 2
Publisher : UI Scholars Hub

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Abstract

Obesity is a significant global health challenge, with adverse impacts on cardiometabolic health such as hypertension, dyslipidemia, and insulin resistance. One promising intervention in obesity management is intermittent fasting (PI). However, scientific evidence on the impact of IF on cardiometabolic health is still limited. This study used a scoping review design to evaluate the association between IF and cardiometabolic health in obese adults. Reference sources are available in English at least abstract between 2015–2023 as well as from PubMed and Google Scholar web sources. The search keywords on PubMed are "Adult AND intermittent fasting AND cardiometabolic" and on Google Scholar is "Intermittent fasting and cardiovascular relationships". A total of 6 articles were analyzed in this context presented in the form of tables including countries and authors, study design, participant characteristics, IF assessment on cardiometabolic states and their results. The study showed that IF methods such as Alternate Day Fasting (ADF), Time-Restricted Feeding (TRF), and the 5:2 method had different effects on cardiometabolic health. ADF is superior in weight loss, while TRF is more effective at lowering triglyceride levels. The 5:2 method showed a significant reduction in waist circumference and oxidative stress. The mechanism of IF benefits involves modulation of the gut microbiota and reduction of systemic inflammation. These results demonstrate the potential of IF as a non-pharmacological approach to manage obesity and its cardiometabolic complications. However, studies with large-scale trial designs and longer intervention durations are needed to develop standard guidelines and ensure the sustainability of IF benefits.