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All Journal Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Jurnal Pengabdian Masyarakat (ABDIRA) EJOIN : Jurnal Pengabdian Masyarakat
Armadany, Fery Indradewi
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan

 1 
Formulasi dan Uji Stabilitas Lotion Antioksidan dari Ekstrak Etanol Rambut Jagung (Zea mays L.) sebagai Antioksidan dan Tabir Surya Armadany, Fery Indradewi; Musnina, Wa Ode Sitti; Wilda, Ulfa
Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Vol 5, No 1 (2019): Pharmauho
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.424 KB) | DOI: 10.33772/pharmauho.v5i1.8996

Abstract

Rambut jagung merupakan limbah tanaman pertanian yang belum banyak dimanfaatkan. Salah satu khasiat rambut jagung yang dapat dimanfaatkan adalah sebagai antioksidan. Penelitian ini bertujuan untuk memformulasikan dan mengetahui stabilitas fisik lotion dari ekstrak etanol rambut jagung (Zea mays L.) sebagai antioksidan dan tabir surya. Ekstrak etanol rambut jagung diperoleh dengan cara maserasi menggunakan etanol 96%. Ekstrak diuji aktivitas antioksidannya dengan menggunakan metode DPPH diperoleh nilai IC50  sebesar 114,75 μg/mL. Lotion dibuat dengan konsentrasi ekstrak ekstrak 1,5%, 3%, dan 4,5%. Nilai IC50 dari masing-masing sediaan berturut-turut yaitu 111,68 μg/mL, 110,10μg/mL, dan 109,63μg/mL.sedangkan nilai SPF dari sediaan lotion berturut-turut yaitu 8,48; 8,78; dan 9,44. Sediaan lotion yang telah diformulasi selanjutnya dilakukan evaluasi karakteristik fisik dan kestabilan lotion sebelum dan sesudah cycling test selama 6 siklus. Evaluasi karakteristik fisik meliputi pengamatan organoleptik,  pengujian pH, viskositas, homogenitas dan daya sebar serta iritasi. Hasil evaluasi menunjukkan bahwa lotion secara keseluruhan stabil sebelum dan setelah dilakukan cycling test dimana sediaan yang dihasilkan berupa lotion dengan warna putih hingga coklat muda dengan bau khas, memiliki konsistensi  kental dan homogen, pH berkisar 5,91–6,63, daya sebar 12.000–17.000 cPs (sesuai dengan SNI untuk viskositas sediaan lotion), daya sebar 5,2–7,2 cm.  Hasil uji iritasi tidak menunjukkan adanya reaksi iritasi.Kata kunci: rambut jagung, lotion, antioksidan, tabir surya
Physical Stability of Hair Tonic Contain Ethanol Extract Galangal (Alpinia galanga L.) Rhizome and Aloe Vera Leaf Filtrate (Aloe vera L.) Akib, Nur illiyin; Tendri Adjeng, Andi Nafisah; Lakasa, Rahiswari Pramudita; Suryani, Suryani; Sartinah, Ari; Ritonga, Halimahtussaddiyah; Armadany, Fery Indradewi
Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan Vol 6, No 2 (2020): Pharmauho
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/pharmauho.v6i2.12054

Abstract

AbstractFormulation and stability testing of hair tonic contain galangal rhizome (Alpinia galanga L.) ethanol extract and Aloe vera L. filtrate has been done as alternative for dandruff removal and hair growth. This study aimed to produce stable hair tonic. Galangal rhizome extract obtained by maceration method using ethanol and aloe leaf filtrate obtained by filtering. Extracts and filtrates characterized include water and ethanol soluble content, water and ash content. Hair tonic was formulated by mechanical mixing method with variations of galangal rhizome ethanol extract and aloe vera leaf filtrate which were 4% and 12.5%; 5% and 25%; 6% and 37.5%. Hair tonic prepared were tested for stability by cycling test method including organoleptic, homogeneity, pH, and viscosity. The characteristics of the galangal rhizome ethanol extract were 12% water soluble extract, 12% ethanol soluble extract, 3% water content, and 2% ash content. The characteristics of Aloe vera leaf filtrate were 10% ethanol soluble extract, 1.6% water soluble extract, and 1% ash content. Stability testing shows that hair tonic preparations are organoleptically stable and homogeneous. The pH values before and after cycling test for formulas A, B, and C were 5.27 to 5.34, respectively; 5.00 to 5.15; and 4.87 to 5.05. Viscosity before and after the cycling test for formulas A, B, and C were 1.178 to 1.676 cPs respectively; 1,306 to 1,883 cPs; and 2,148 to 2,296 cPs. It is concluded that hair tonic prepared are stable based on the requirements of Indonesian National Standard (SNI).
Co-Authors Afriana, Dian Andriani, Kris Annisaa, Nur Ari Sartinah, Ari Fadhliyah Malik Fitrawan, La Ode Muhammad Holidin, Wiwin Jabbar, Asriullah Lakasa, Rahiswari Pramudita MAHMUDAH, RIFA'ATUL Mallarangeng, Andi Nafisah Tendri Adjeng Munasari, Dian Newulasindo, Sri Madani Nining, Nining Nur Illiyin Akib, Nur Illiyin Nurfenti, Nurfenti Pascayantri, Asniar Putri, Riska Damayanti Ringgu, Herdianawati Rismawati Rismawati Ritonga, Halimahtussaddiyah Sawitri, Feny Eka Suryani Suryani Wa Ode Sitti Musnina wahyuni wahyuni Wilda, Ulfa