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All Journal Journal of Biomedicine and Translational Research Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education
Gharini, Putrika Prastuti Ratna
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Correlation Between Corrected TIMI Frame Count with the Extent of Myocardial Fibrosis on ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention Munandar, Reza Maulana; Herminingsih, Susi; Ardhianto, Pipin; Gharini, Putrika Prastuti Ratna; Sobirin, Mochamad Ali
Journal of Biomedicine and Translational Research Vol 10, No 1 (2024): April 2024
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v10i1.20872

Abstract

Background: Microvascular injury after primary percutaneous coronary intervention (PPCI) reperfusion contributes to necrosis propagation. Corrected TIMI Frame Count (CTFC) is a surrogate marker of microvascular dysfunction and can stratify in-hospital mortality risk in patients with final TIMI flow 3. The extent of myocardial fibrosis after STEMI is associated with a higher incidence of major cardiovascular events. This study aimed to determine the relationship between CTFC in the infarct-related artery and myocardial fibrosis area based on cardiac magnetic resonance (CMR) in STEMI patients undergoing PPCI.Methods: This retrospective cohort study included 31 STEMI patients who had undergone PPCI and CMR examination between days 60 and 75 after STEMI as the sample. CTFC was measured in the infarct-related artery from post-PPCI angiogram recordings. Myocardial fibrosis area was measured from late gadolinium enhancement CMR (LGE-CMR) imaging results.Results: In this study, the mean age was 51.61±10.49 years, 90.3% were male, non-anterior infarction location was 58.1%, mean total ischemic time was 489.48±228.33 minutes, mean CTFC was 27.4±9.3 frames, and mean myocardial fibrosis was 18.33±7.87%. There was no significant correlation found between CTFC and myocardial fibrosis (p=0.530), however total ischemic time had a positive and significant correlation with myocardial fibrosis (p=0.025, r=0.403).Conclusion: CTFC in the infarct-related artery is not correlated with myocardial fibrosis area in STEMI patients undergoing PCI.
Innovative Learning Approaches for Medical Students: A Comparative Analysis of Hybrid Learning vs Conventional Lectures Mayasari, Dyah Samti; Hafizhah, Bidhari; Abdullah, Hafidz; Hasana, Shofuro; Alfina, Saski Yasmin; Fatimah, Vita Arfiana Nurul; Solikhah, Hana Maryam; Kokasih, Orisativa; Gharini, Putrika Prastuti Ratna
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 14, No 4 (2025): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.106109

Abstract

Introduction: With the rapid progress of technology, learning approaches have increasingly moved online, including the method for learning electrocardiography (ECG). ECG interpretation is a core skill for physicians, especially in emergency settings. Massive Open Online Courses (MOOCs) provide a flexible and complementary learning method that complements traditional classroom instruction. This study aims to evaluate the effectiveness of MOOCs as a complementary learning method and compare that with conventional learning in enhancing ECG knowledge among second-year preclinical students.Methods: A prospective cross-sectional study with consecutive sampling was conducted to recruit participants. They were divided into a control group (conventional lectures) and an intervention group (using MOOC as a complementary method). All participants are required to complete pre-test and post-test questionnaires, as well as evaluations after each module. This study compared learning gain scores between traditional and hybrid learning methods.Results: Of the 258 participants registered, 160 students completed the learning modules, including the post-test. The majority of participants were female, all under 25 years old, and had been in medical education for 1.5 to 2 years. Overall, the gain score achieved was 2.03 for traditional and 2.75 for hybrid. While the topics of electrolyte imbalance and heart enlargement showed increasing scores, arrhythmia and ECG in ischemia and infarction showed lower scores for the hybrid method. Not all registered participants completed the course; the main factor motivating participants to complete the course was gaining knowledge (80.00%). Conclusion: Hybrid ECG learning using online media, such as video lectures and mini-quizzes, improves interpretation skills more effectively than traditional methods by boosting engagement and knowledge retention. To further enhance learning, integrating artificial intelligence-driven reminders and monitoring can improve completion rates, and continuous updates to the curriculum are necessary to strengthen medical students' ECG competence.
Co-Authors Abdullah, Hafidz Alfina, Saski Yasmin Fatimah, Vita Arfiana Nurul Hafizhah, Bidhari Hasana, Shofuro Herminingsih, Susi Kokasih, Orisativa Mayasari, Dyah Samti Mochamad Ali Sobirin Munandar, Reza Maulana Pipin Ardhianto, Pipin Solikhah, Hana Maryam