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All Journal Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Abdullah, Hafidz
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Pengaruh Suplementasi Probiotik terhadap Luaran Pengobatan Pasien dengan Tuberkulosis Aktif: Sebuah Kajian Sistematis Pake, Indry Agatha Rihi; Abdullah, Hafidz; Fahreza, Lufthi; Suwandi, Jeremiah; Faisal, Zuresh Shafira Sharafina; Karidza, Bilqish; Lazarus, Gilbert
Majalah Kedokteran Indonesia Vol 75 No 1 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.1-2025-1390

Abstract

Introduction: Tuberculosis, one of the most globally burdensome infectious diseases, poses high mortality and morbidity risks due to the adverse effects of treatment and disease-related complications, resulting in poor treatment adherence. Despite probiotics, treatment supplements containing live bacteria and having known immunomodulatory effects, their impact on tuberculosis therapy remains understudied. Hence, this systematic review aims to explore the effect of probiotic supplementation on the outcomes of active tuberculosis therapy, including but not limited to its effectiveness in improving tuberculosis treatment and host immunity, as well as its adverse events. Method: A systematic review was performed by searching relevant primary clinical studies from PubMed, Embase, Google Scholar, and Clinicaltrials.gov. The included studies were assessed for risk of bias with the Revised Cochrane risk-of-bias tool for randomized trials, and the findings were synthesized qualitatively. Results: A total of five randomized controlled trials involving 926 patients were included in this systematic review. Our findings revealed that Lactobacillus casei probiotic supplementation significantly reduced the incidence and duration of gastrointestinal side effects during tuberculosis therapy, particularly vomiting, decreased appetite, and constipation. Additionally, probiotics displayed the potential to enhance immunity by increasing lymphocyte cell counts, downregulating proinflammatory cytokines, maintaining immunoglobulin A levels in saliva, mitigating oxidative stress in gastrointestinal organs, and ameliorating gut dysbiosis. Conclusion: These results highlight the advantageous impact of probiotics on active tuberculosis therapy outcomes. Further studies involving a more heterogeneous population investigating the adverse effects following probiotics use, and the long-term effects of probiotics supplementation are required to substantiate our findings.
Innovative Learning Approaches for Medical Students: A Comparative Analysis of Hybrid Learning vs Conventional Lectures Mayasari, Dyah Samti; Hafizhah, Bidhari; Abdullah, Hafidz; Hasana, Shofuro; Alfina, Saski Yasmin; Fatimah, Vita Arfiana Nurul; Solikhah, Hana Maryam; Kokasih, Orisativa; Gharini, Putrika Prastuti Ratna
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 14, No 4 (2025): December
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.106109

Abstract

Introduction: With the rapid progress of technology, learning approaches have increasingly moved online, including the method for learning electrocardiography (ECG). ECG interpretation is a core skill for physicians, especially in emergency settings. Massive Open Online Courses (MOOCs) provide a flexible and complementary learning method that complements traditional classroom instruction. This study aims to evaluate the effectiveness of MOOCs as a complementary learning method and compare that with conventional learning in enhancing ECG knowledge among second-year preclinical students.Methods: A prospective cross-sectional study with consecutive sampling was conducted to recruit participants. They were divided into a control group (conventional lectures) and an intervention group (using MOOC as a complementary method). All participants are required to complete pre-test and post-test questionnaires, as well as evaluations after each module. This study compared learning gain scores between traditional and hybrid learning methods.Results: Of the 258 participants registered, 160 students completed the learning modules, including the post-test. The majority of participants were female, all under 25 years old, and had been in medical education for 1.5 to 2 years. Overall, the gain score achieved was 2.03 for traditional and 2.75 for hybrid. While the topics of electrolyte imbalance and heart enlargement showed increasing scores, arrhythmia and ECG in ischemia and infarction showed lower scores for the hybrid method. Not all registered participants completed the course; the main factor motivating participants to complete the course was gaining knowledge (80.00%). Conclusion: Hybrid ECG learning using online media, such as video lectures and mini-quizzes, improves interpretation skills more effectively than traditional methods by boosting engagement and knowledge retention. To further enhance learning, integrating artificial intelligence-driven reminders and monitoring can improve completion rates, and continuous updates to the curriculum are necessary to strengthen medical students' ECG competence.
Co-Authors Alfina, Saski Yasmin Fahreza, Lufthi Faisal, Zuresh Shafira Sharafina Fatimah, Vita Arfiana Nurul Gharini, Putrika Prastuti Ratna Hafizhah, Bidhari Hasana, Shofuro Karidza, Bilqish Kokasih, Orisativa Lazarus, Gilbert Mayasari, Dyah Samti Pake, Indry Agatha Rihi Solikhah, Hana Maryam Suwandi, Jeremiah