Panjaitan, Fransiska Uli Arta
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EFEK ANTIBAKTERI EKSTRAK FLAVONOID PROPOLIS KELULUT (Geniotrigona thorasica) TERHADAP Aggregatibacter actinomycetemcomitans (studi in vitro melalui metode dilusi) Ardiana, Ardiana; Oktiani, Beta Widya; Panjaitan, Fransiska Uli Arta
Dentin Vol 3, No 2 (2019)
Publisher : Universitas Lambung Mangkurat

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Abstract

INHIBITORY TEST OF FLAVONOID PROPOLIS KELULUT EXTRACTS (G. thorasica) ON Porphyromonas gingivalis AS AN ETIOLOGIC FACTOR OF CHRONIC PERIODONTITIS Valentina, Ursula; Oktiani, Beta Widya; Panjaitan, Fransiska Uli Arta
Dentino : Jurnal Kedokteran Gigi Vol 4, No 2 (2019)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v4i2.7065

Abstract

Background: Natural ingredients have been used recently for its ability in curing various diseases and reducing the risk of antibiotic resistance. One of these natural ingredients is propolis. Bee propolis Geniotrigona thorasica from South Kalimantan has a strong antibacterial activity with active compounds such as flavonoids. Flavonoids can damage cell membranes and can fight the expansion of β-lactamase enzyme produced by gram-negative bacteria. Porphyromonas gingivalis is a gram-negative bacterium that causes chronic periodontitis with a prevalence of 80%. Objective: This study was to find out the inhibitory test of flavonoid propolis kelulut extract at the concentration of 0.1%; 0.3% and 0.5% on Porphyromonas gingivalis bacteria. Method: This type of research used a pure experimental method with post-test only and control group design. One-way ANOVA statistical test was performed with follow-up test of Post Hoc Dunnet’s T3. Treatment was given to 4 groups with 5 repetitions. Observations were carried out using digital calipers in all groups after incubation for 24 hours with a temperature of 37℃. Results: One Way Anova and Post Hoc Dunnet's T3 showed significant differences in the diameter flavonoid propolis extract inhibitory zone against Porphyromonas gingivalis. The average value of Flavonoid extract inhibitory zone after 24 hours observation with a concentration of 0.5%; 0.3%; 0.1% and sterile distilled water were 25.24 mm; 18.04 mm; 13.58 mm and there was no inhibitory zone observed in sterile distilled water group. Conclusion: Extract of flavonoid propolis kelulut at the concentration of 0.1%; 0.3% and 0.5% can inhibit the growth of Porphyromonas gingivalis as an etiologic factor of chronic periodontitis.
ANTIBACTERIAL EFFECTIVENESS OF LIME PEEL (Citrus hystrix) EXTRACT GEL ON Porphyromonas gingivalis BACTERIES Asmik Ara, M. Rizky Nuari; Oktiani, Beta Widya; Wardani, Ika Kusuma; Dewi, Renie Kumala; Panjaitan, Fransiska Uli Arta
Dentino: Jurnal Kedokteran Gigi Vol 10, No 2 (2025)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v10i2.24167

Abstract

Background: Periodontitis is an inflammation of the tooth-supporting tissues caused by microorganisms, especially Porphyromonas gingivalis. Porphyromonas gingivalis has resistance to many antibiotics. Kuit lime peel has potential as an antibacterial with the most compound content is triterpenoid. Objective: To measure and analyze the effectiveness of antibacterial gel of kuit lime peel extract (Citrus hystrix) on the growth of Porphyromonas gingivalis bacteria. Methods: This study is a laboratory experimental study with post test with control group design, using seven treatment groups, namely 5%, 10%, 20% kecapi leaf extract, and metronidazole positive control with 7 repetitions of each treatment. Antibacterial effectiveness uses the disc diffusion method which is seen from the diameter of the inhibition zone formed on Mueller Hinton Agar media. Results: Based on the results of Kruskal-Wallis and Post hoc Mann Whitney tests, there were significant differences between concentration groups of 5%, 10%, 20%, and metronidazole. Conclusion: Lime peel extract gel (Citrus Hystrix) concentrations of 5%, 10%, and 20% have antibacterial potential against Porphyromonas gingivalis bacteria. Keywords: kuit lime peel extract, antibactery, porphyromonas gingivalis