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All Journal Majalah Kedokteran Gigi Indonesia Dentino: Jurnal Kedokteran Gigi Dentin Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI)
Oktiani, Beta Widya
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Dentistry Energy Health Professions Medicine & Pharmacology Physics

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EFEK ANTIBAKTERI EKSTRAK FLAVONOID PROPOLIS KELULUT (Geniotrigona thorasica) TERHADAP Aggregatibacter actinomycetemcomitans (studi in vitro melalui metode dilusi) Ardiana, Ardiana; Oktiani, Beta Widya; Panjaitan, Fransiska Uli Arta
Dentin Vol 3, No 2 (2019)
Publisher : Universitas Lambung Mangkurat

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Abstract

INHIBITORY TEST OF FLAVONOID PROPOLIS KELULUT EXTRACTS (G. thorasica) ON Porphyromonas gingivalis AS AN ETIOLOGIC FACTOR OF CHRONIC PERIODONTITIS Valentina, Ursula; Oktiani, Beta Widya; Panjaitan, Fransiska Uli Arta
Dentino : Jurnal Kedokteran Gigi Vol 4, No 2 (2019)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v4i2.7065

Abstract

Background: Natural ingredients have been used recently for its ability in curing various diseases and reducing the risk of antibiotic resistance. One of these natural ingredients is propolis. Bee propolis Geniotrigona thorasica from South Kalimantan has a strong antibacterial activity with active compounds such as flavonoids. Flavonoids can damage cell membranes and can fight the expansion of β-lactamase enzyme produced by gram-negative bacteria. Porphyromonas gingivalis is a gram-negative bacterium that causes chronic periodontitis with a prevalence of 80%. Objective: This study was to find out the inhibitory test of flavonoid propolis kelulut extract at the concentration of 0.1%; 0.3% and 0.5% on Porphyromonas gingivalis bacteria. Method: This type of research used a pure experimental method with post-test only and control group design. One-way ANOVA statistical test was performed with follow-up test of Post Hoc Dunnet’s T3. Treatment was given to 4 groups with 5 repetitions. Observations were carried out using digital calipers in all groups after incubation for 24 hours with a temperature of 37℃. Results: One Way Anova and Post Hoc Dunnet's T3 showed significant differences in the diameter flavonoid propolis extract inhibitory zone against Porphyromonas gingivalis. The average value of Flavonoid extract inhibitory zone after 24 hours observation with a concentration of 0.5%; 0.3%; 0.1% and sterile distilled water were 25.24 mm; 18.04 mm; 13.58 mm and there was no inhibitory zone observed in sterile distilled water group. Conclusion: Extract of flavonoid propolis kelulut at the concentration of 0.1%; 0.3% and 0.5% can inhibit the growth of Porphyromonas gingivalis as an etiologic factor of chronic periodontitis.
THE EFFECTS OF PANORAMIC RADIOGRAPHY ONGINGIVAL CREVICULAR FLUIDVOLUME IN WISTAR RATS WITH PERIODONTITIS Ramadhanty, Aina; Aspriyanto, Didit; Oktiani, Beta Widya
Dentino : Jurnal Kedokteran Gigi Vol 6, No 1 (2021)
Publisher : FKG Unlam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v6i1.10632

Abstract

ABSTRACTBackground: Panoramic radiography is one of the most commonly used radiographic diagnostic tools. Panoramic radiography exposure can increase the GCF flow because of increasing vascular permeability.GCF flow can also increase in periodontitis conditions. Objective: The purpose of this study was to analyze the effects of 1, 2, and 3 times exposure of panoramic radiography to the volume of GCF in wistar rats with periodontitis. Method: This research was true experimental with post test onlycontrol group design. Thesampling technique used simple random samplingthat obtained 25 wistar rats comprising of 5 wistars from each group in which the GCF samples of each group was collected from. Results: The average number of GCF inhealthy rats groupthat was not exposed to panoramic radiographywas 0.114 µL, the periodontitis rats group that was not exposed to panoramic radiography was 0.246 µL, the periodontitis rats group that was exposed1 time was 0.286 µL, the group of periodontitis rats exposed 2 times was 0.294 µL, and periodontitis group of rats exposed 3 times was 0.374 µL. The results of the One-Way Anova and Post Hoc Bonferroni tests stated that there is a significant increase in the volume of GCF between the control group and all other treatment groups, as well as between the non-exposed periodontitis group and the periodontitis group with 3 times exposure. Conclusion: Panoramic radiography can causeincrease the volume of GCF in wistar rats with periodontitis. Keywords: Gingival Crevicular Fluid,panoramic, periodontitis, wistar rats
Relationship between peatland water use and periodontal disease in Daha Selatan Subdistrict Hidayah, Antung Nurul; Oktiani, Beta Widya; Azizah, Aulia
Majalah Kedokteran Gigi Indonesia Vol 8, No 3 (2022): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.76843

Abstract

Periodontal disease is one of the dental and oral health problems in Hulu Sungai Selatan Regency with a prevalence of gingivitis of 24.58% and periodontitis of 10.83%. One of the risk factors for periodontal disease is the use of peatland water. Peatland water has a low pH which can affect the colony of anaerobic bacteria in the oral cavity of the water users. Bacteria that cause periodontal disease are able to develop and survive in acidic conditions. This study aimed to analyze the relationship between peatland water use and periodontal disease in Daha SelatanSubdistrict. This was analytical research with a cross-sectional approach. The sampling technique used a simple random sampling technique with a total sample of 100 people (n = 100) who were residents aged 35-44 years in Daha Selatan Subdistrict. The results showed that the participants with high use of peatland water showedthe highest percentage (39%). In addition, there were 61% respondents who suffered from periodontal disease. ChiSquare test obtained a significance value of 0.022 (p < 0.05), showing that there was a relationship between peatland water use and periodontal disease. The risk of periodontal disease in the respondents who used peatland water in the high category was 4.167 times greater than in the respondents who did not use peatland water. It is essential to educate the general public about the effects that using peatland water can have on dental and oral health because there is a high prevalence of periodontal disease, which is caused by the widespread use of peatland water.
TOXICITY TEST OF Eusideroxylon zwageri BARK EXTRACT BASED ON LIVER HISTOPATHOLOGY HYDROPIC DEGENERATION AND NECROSIS Azminida, Dhiya Salma; Firdaus, I Wayan Arya Krishnawan; Utami, Juliyatin Putri; Oktiani, Beta Widya; Wydiamala, Erida
Dentino: Jurnal Kedokteran Gigi Vol 9, No 2 (2024)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v9i2.20400

Abstract

Background: Ironwood bark extract contains antioxidant properties such as flavonoids, phenolics, and proanthocyanidins, which can stabilize ROS in the body and help accelerate wound healing. The liver plays a role in nutrient metabolism, detoxification, and ROS production. The lack of antioxidants to neutralize excess ROS makes the liver vulnerable to damage. Purpose: This study aimed to determine that there was no toxic effect of giving ironwood bark extract (Eusideroxylon zwageri) doses of 1.250 mg/kg, 2.750 mg/kg, and 4.750 mg/kg on the liver of Wistar rats based on histopathological features of hydropic degeneration and necrosis. Methods: Pure laboratory experimental quantitative (true experimental) with a post-test-only research design with control group design and One Way Anova statistical test. Treatment was given to 4 groups, namely group (K) was given aquadest control, group (T1) was given ironwood bark extract at a dose of 1.250 mg/kgBW, group (T2) was given ironwood bark extract at a dose of 2.750 mg/kgBW, and group (T3) given ironwood bark extract at a dose of 4.750 mg/kgBW. Results: The results showed no significant difference between the four treatment groups based on the average percentage of hydropic degeneration and necrosis. Conclusion: There was no toxic effect of giving ironwood bark extract doses of 1.250 mg/kgBW, 2.750 mg/kgBW, and 4.750 mg/kgBW on the liver of Wistar rats based on histopathological appearance of hydropic degeneration and necrosis for 14 days.
ANTIBACTERIAL EFFECTIVENESS TEST OF KECAPI LEAVES EXTRACTS (Sandoricum koetjape) AGAINST THE GROWTH OF Porphyromonas gingivalis Fitria, Novita Nanda; Oktiani, Beta Widya; Azizah, Aulia
Dentino: Jurnal Kedokteran Gigi Vol 9, No 1 (2024)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v9i1.18855

Abstract

Background: Chronic periodontitis is a disease of the oral cavity that is influenced by the presence of plaque bacteria caused by Porphyromonas gingivalis which can cause chronic infection of the periodontal tissue. Kecapi leaf (Sandoricum koetjape) extract contains active compounds in the form of flavonoids, saponins, alkaloids, steroids, phenolics, and triterpenoids which function as antibacterial against the growth of Porphyromonas gingivalis. Kecapi leaf extract is used as an alternative to using herbal gluconate to prevent infection caused of Porphyromonas gingivalis. Purpose: To determine the antibacterial effectiveness of kecapi leaf extract against bacterial growth of Porphyromonas gingivalis. Methods: This study used a pure experimental research (true experimental) with post-test only with control design, consists of 7 treatment groups, including: concentrated kecapi leaf extract 5%, 10%, 15%, 25%, 50%, chlorhexidine gluconate 0.2% as positive control, and distilled water as negative control. It was repeated 7 times, the antibacterial effectiveness was assessed from Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) on BHIB and NA media by dilution method. Results: MIC on kecapi leaf extract at a concentration of 5% showed the smallest result of -0.147 and the MBC value at a concentration of 50% did not show the growth of bacterial colonies. Conclusion: Kecapi leaf extract with concentrations of 5%, 10%, 15%, 25%, 50%, and positive control was effective in inhibiting and killing bacterial growth of Porphyromonas gingivalis. Keywords: Antibacterial, Kecapi leaf extract, Porphyromonas gingivalis
Differences of Gonial Index value in male and female hypertension patients using panoramic radiography Widiawati, Shely Desia; Sarifah, Norlaila; Oktiani, Beta Widya; Taufiqurrahman, Irham; Sukmana, Bayu Indra
Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) Vol 7 No 3 (2023): Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI)
Publisher : Ikatan Radiologi Kedokteran Gigi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jrdi.v7i3.1091

Abstract

Objectives: This study is aimed to measure the Gonial index (GI) value in male and female hypertensive patients using panoramic radiography. Materials and Methods: This is a comparative analytical research. The sampling technique used was the purposive sampling technique. The sample of this study was primary data from panoramic radiographs of hypertensive patients who had been X-rayed at the Radiology Installation of Ulin General Hospital, Banjarmasin. Results: There was no significant difference in the gonial index (GI) values between men (17.83 mm) and women (19.17 mm), with the size of the right region of the female 20.33 mm and the left of the female 16.67 mm and the size of the right region of the male is 17.03 mm and the left male is 19.97 mm. Conclusion: There was no significant difference between the gonial index (GI) values ​​between women and men, although the decrease of bone density in women is higher than in men.
NANO-HYDROXYAPATITE AND HYDROXYCHAVICOL'S COMBINED EFFECT IN Streptococcus mutans GROWTH Dewi, Nurdiana; Oktiani, Beta Widya; Tri Putri, Deby Kania; Amelia, Aura; Zahra, Aisyah Nur
Dentino: Jurnal Kedokteran Gigi Vol 10, No 1 (2025)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v10i1.22207

Abstract

Background: Early childhood caries is an aggressive form of dental caries that affects children under six years old. The increasing prevalence of ECC caused by Streptococcus mutans highlights the need for effective antimicrobial agents. Objective: To evaluate the antibacterial activity of a combination of nanohydroxyapatite (nHAp) and hydroxychavicol (HC) against S. mutans. Methods: 100 mg/mL nHAp was combined with HC at 0.125, 0.25, 0.5, and 1 mg/mL concentrations. DMSO 5% was used as the negative control. S. mutans ATCC 25175 was cultured in Brain Heart Infusion (BHI) media. Minimum Inhibitory Concentration (MIC) was determined using a UV-Vis spectrophotometer to measure absorbance differences. Minimum Bactericidal Concentration (MBC) was established by plating onto BHI agar and counting the colony count.  Results: The results showed that MIC occurred at a combination of nHAp 100 mg/mL + HC 0.125 mg/mL, while MBC was achieved at nHAp 100 mg/mL + 1 mg/mL HC, where no bacterial colonies were observed. Statistical analysis using ANOVA and Bonferroni post-hoc tests revealed significant differences in both absorbance reduction and colony counts between groups (p < 0.05), confirming the dose-dependent antibacterial efficacy of the nHAp-HC combination. Conclusion: These findings indicate that the synergistic action of nHAp and HC offers a promising strategy for controlling ECC, particularly by targeting the growth of S. mutans. Further, in vivo studies are recommended to explore clinical applicability and long-term safety.
ANTIBACTERIAL EFFECTIVENESS OF LIME PEEL (Citrus hystrix) EXTRACT GEL ON Porphyromonas gingivalis BACTERIES Asmik Ara, M. Rizky Nuari; Oktiani, Beta Widya; Wardani, Ika Kusuma; Dewi, Renie Kumala; Panjaitan, Fransiska Uli Arta
Dentino: Jurnal Kedokteran Gigi Vol 10, No 2 (2025)
Publisher : FKG ULM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentino.v10i2.24167

Abstract

Background: Periodontitis is an inflammation of the tooth-supporting tissues caused by microorganisms, especially Porphyromonas gingivalis. Porphyromonas gingivalis has resistance to many antibiotics. Kuit lime peel has potential as an antibacterial with the most compound content is triterpenoid. Objective: To measure and analyze the effectiveness of antibacterial gel of kuit lime peel extract (Citrus hystrix) on the growth of Porphyromonas gingivalis bacteria. Methods: This study is a laboratory experimental study with post test with control group design, using seven treatment groups, namely 5%, 10%, 20% kecapi leaf extract, and metronidazole positive control with 7 repetitions of each treatment. Antibacterial effectiveness uses the disc diffusion method which is seen from the diameter of the inhibition zone formed on Mueller Hinton Agar media. Results: Based on the results of Kruskal-Wallis and Post hoc Mann Whitney tests, there were significant differences between concentration groups of 5%, 10%, 20%, and metronidazole. Conclusion: Lime peel extract gel (Citrus Hystrix) concentrations of 5%, 10%, and 20% have antibacterial potential against Porphyromonas gingivalis bacteria. Keywords: kuit lime peel extract, antibactery, porphyromonas gingivalis
Co-Authors Amelia, Aura Ardiana Ardiana, Ardiana Asmik Ara, M. Rizky Nuari Aspriyanto, Didit Aulia Azizah Azminida, Dhiya Salma Bayu Indra Sukmana Dewi Nurdiana Dewi, Renie Kumala Firdaus, I Wayan Arya Krishnawan Fitria, Novita Nanda Hidayah, Antung Nurul Ika Kusuma Wardani Panjaitan, Fransiska Uli Arta Ramadhanty, Aina Sarifah, Norlaila Tri Putri, Deby Kania Utami, Juliyatin Putri Valentina, Ursula Widiawati, Shely Desia Wydiamala, Erida Zahra, Aisyah Nur