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All Journal MEDISAINS Science and Technology Indonesia Jurnal Penelitian Sains Jurnal Fitofarmaka Indonesia Jurnal Pengabdian Masyarakat Indonesia
Solihah, Indah
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Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Engineering Environmental Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Journal : Science and Technology Indonesia

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A Cytotoxic Activity of Tahongai (Kleinhovia hospita Linn.) Leaves Extracts Using Brine Shrimp Lethality Test Solihah, Indah; Herlina, Herlina; Rasyid, Riana Sari Puspita; Suciati, Tri; Khairunnisa, Khairunnisa
Science and Technology Indonesia Vol 4 No 3 (2019): July
Publisher : ARTS Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1489.712 KB) | DOI: 10.26554/sti.2019.4.3.60-63

Abstract

Tahongai (Kleinhovia hospita Linn.) leaves had been known contain alkaloids, flavonoids, saponins, steroids, and tannins. At Komering, South Sumatera tribe, tahongai leaves had been known to treat tumor, cancer, polyps, acne, and dysmenorrhea. The study of cytotoxic activity of tahongai bark and stem were done. This study aims to determine the cytotoxic activity of tahongai leaves extracts using BSLT method. Tahongai leaves were extracted using gradual maceration with n-hexane, ethyl acetate, and ethanol 96%. Each extract was tested cytotoxic activity towards Artemia salina L. larvae. The yield of n-hexane, ethyl acetate, and ethanol extracts are 2,686%, 7,033%, and 7,933% respectively. Ethanol extract of tahongai leaves had the best cytotoxic activity with lethality value 76,667% at 500ppm. Statistical analysis with two way ANOVA showed extract and concentration had a significant (p<0,05) effect on larvae lethality percentage.
Co-Authors Fertilita, Soilia Herlina Herlina Khairunnisa Khairunnisa Mardiyanto Mardiyanto Mareta, Fauzia Munawwaroh, Inayatul Nirwan Syarif, Nirwan Puspita Rasyid, Rianasari Rasyid, Riana Sari Puspita Resmiyani, Ubbadah Sari, Familia Maya Shaum Shiyan Tri Suciati