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All Journal Jurnal Kedokteran Brawijaya Jurnal Kesehatan Reproduksi Indonesian Journal of Medicine Medica Hospitalia
Soejoenoes, Ariawan
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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The Effect of Chayote Extract (Sechium edule) On Blood Pressure in Pregnant Women with Hypertension Fauziah, Nur Alfi; Hidajati, Kamilah; Soejoenoes, Ariawan
Indonesian Journal of Medicine Vol 4, No 3 (2019)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (642.878 KB)

Abstract

Background: Increased blood pressure of pregnant women during pregnancy is one of the high risks during pregnancy which can lead to preeclampsia, eclampsia to maternal and infant mortality. One of the treatments recommended by pregnant women is to consume foods containing potassium and flavonoids, namely squash. This study aimed to determine the effect of squash pumpkin on changes in blood pressure of hypertensive mothers in pregnancy in the health center in Semarang City area.Subjects and Methods: This was an experimental study. The study was conducted at community health centers in Semarang, Central Java, from March to May 2018. A sample of 20 pregnant women who experienced hypertension in pregnancy was divided into two groups, control and treatment groups. The dependent variable was blood pressure. The independent variable was the extract of chayote. The data were analyzed by multiple linear regression.Results: There were differences in systolic blood pressure before and after the administration of squash extract (p<0.001). There are differences in Diastolic blood pressure before and after the administration of squash extract (p <0.001).Conclusion: Consuming chayote can make an effort to help lower blood pressure in pregnant women with hypertension. Keywords: flavonoids, hypertension in pregnancy, potassium, squash, blood pressure. Correspondence: Nur Alfi Fauziah. Postgraduate Midwifery Program, School of Health Polytechnics. Jl. Tirto Agung, Pedalangan, Banyumanik, Semarang City, 50268, Central Java, Indonesia. Email: nuralfifau­ziah24­@yahoo.com.Indonesian Journal of Medicine (2019), 4(3): 266-277https://doi.org/10.26911/theijmed.2019.04.03.10
Kualitas Rujukan Bidan Delima di RSU A.W. Sjahranie, Samarinda Ginting, Erwin; Soejoenoes, Ariawan; Siswosudarmo, Risanto; Malinta, Umar
JURNAL KESEHATAN REPRODUKSI Vol 6, No 2 (2019)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.886 KB) | DOI: 10.22146/jkr.46606

Abstract

Latar Belakang: Angka kematian ibu merupakan indikator tingkat kesehatan, di mana di Indonesia angka ini masih tinggi. Bidan Delima adalah salah satu program nasional dalam upaya menurunkan angka kemaitian ibu ini.Tujuan: Membandingkan ketepatan rujukan pasien Bidan Delima dengan Bidan Non-Delima serta luaran meternal dan neonatalnya.Metode: Penelitian ini dilaksanakan di Rumah Sakit Umum Abdul Wahab Sjahranie Samarinda. Pasien yang dirujuk oleh Bidan Delima digunakan sebagai kelompok kasus sedangkan pasien yang dirujuk oleh bidan Non-Delima digunakan sebagai kontrol. Penelitian ini menggunakan studi Cross Sectional. Ukuran sampel dihitung untuk mendapatkan tipe satu 0,05, kekuatan 0,80 dan perbedaan proporsi sekitar 30%. Pengolahan data menggunakan alat pengolah data di komputer. Chi-Square dan regresi logistik digunakan untuk analisa statistik.Hasil dan Pembahasan: Sebanyak 189 pasien yang memenuhi syarat yang terdiri dari 66 pasien Bidan Delima dan 123 pasien Bidan Non-Delima digunakan. Pasien tepat waktu yang dirujuk oleh Bidan Delima adalah 63,6% dibandingkan dengan 72,4% oleh Bidan Non-Delima, memberikan RP 0,88 (95% CI 0,71-1,09). Angka kelahiran vaginal masing-masing adalah 54,5% dan 66,7% pada Bidan Delima dan Non-Delima masing-masing (RP 0,82; 95% CI 0,64-1,05). Tingkat bayi bugar masing-masing  adalah 78,8% dan 86,2% pada Bidan Delima dan Non-Delima (RP 0,91; 95%  CI 0,79-1,05).Simpulan: Tidak ada perbedaan ketepatan rujukan, luaran maternal dan neonatal antara Bidan Delima dan Bidan Non-Delima.Kata Kunci: Bidan Delima; Non-Delima; Ketepatan Rujukan  
Efikasi Misoprostol Rektal Intraoperasi Seksio Cesarea Versus Oksitosin dalam Mengurangi Jumlah Perdarahan untuk Mencegah Perdarahan Post Partum Milhan, Milhan; Soejoenoes, Ariawan; Prawitasari, Shinta
JURNAL KESEHATAN REPRODUKSI Vol 6, No 2 (2019)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.344 KB) | DOI: 10.22146/jkr.48773

Abstract

Latar Belakang : Perdarahan post partum adalah salah satu etiologi kematian ibu. Setelah operasi caesar, uterotonik dalam bentuk infus oksitosin (20-40 IU) atau misoprostol rektal (200-600 μg) diberikan untuk kontraksi uterus pasca operasi pada pasien pada risiko perdarahan post partum. Penelitian ini dibuat membandingkan kedua agen uterotonik  tersebut.Tujuan : Mengetahui perbandingan penggunaan misoprostol rektal tiga tablet (600 ugr) dan penggunaan oksitosin 20 IU  selama operasi seksio cesarea dalam mengurangi jumlah perdarahan untuk mencegah perdarahan post partum di fasilitas kesehatan tingkat lanjut.Metode : Penelitian ini adalah  double blind randomised controlled trial. Populasi penelitian adalah pasien rawat inap ruang kebidanan dan kandungan RSUD Datu Sanggul, Rantau. Besar sampel ditentukan dengan rumus Kirkwood dan Steme sebesar 98. Secara acak peserta dibagi ke kelompok misoprostol dan oksitosin. Farmasi menyediakan obat penelitian dan plasebo dalam bentuk yang tidak dapat dikenali. Untuk kelompok misoprostol disiapkan tablet misoprostol 600 μg untuk digunakan secara rektal ditambah spuit yang sudah diisi sebelumnya larutan saline normal. Kelompok oksitosin disiapkan tablet plasebo untuk digunakan secara rektal ditambah jarum suntik dengan oksitosin 20 IU dan larutan normal saline.Hasil dan Pembahasan: Didapatkan kelompok 1 (misoprostol) dari 42 sampel, yang mengalami perdarahan kurang dari 1000 ml sebanyak 41 sampel (97,6%) dan yang perdarahan lebih dari atau sama dengan 1000 ml sebanyak 1 sampel (2,38%). Sedangkan kelompok 2 (oksitosin) dari 42 sampel yang mengalami perdarahan kurang dari 1000 ml sebanyak 36 sampel (85,7% ) dan yang perdarahan lebih dari 1000 ml sebanyak 6 sampel  (14,3% )Kesimpulan: Ada perbedaan bermakna antara jumlah perdarahan kelompok misoprostol dengan jumlah perdarahan kelompok oksitosin. Karena mean rank kelompok misoprostol lebih rendah dapat disimpulkan bahwa: “Jumlah perdarahan pada penggunaan misoprostol rektal tiga tablet (600 ugr) lebih sedikit dibanding penggunaan oksitosin 20 IU selama operasi seksio cesarea”. Di antara variabel-variabel perancu, riwayat partus lama dan adanya faktor keterlambatan, berhubungan dengan  jumlah perdarahan. Variabel yang dapat digunakan untuk memprediksi jumlah atau banyaknya perdarahan adalah variabel “ada terlambat/tidak”. Kata Kunci: Jumlah Perdarahan, Oksitosin, Misoprostol, Perdarahan Postpartum
Iron Status of Newborns and Umbilical Cord Blood Hepcidin Levels in Gender Differences Santosa, Qodri; Soemantri, AG; Hadisaputro, Soeharyo; Soejoenoes, Ariawan
Jurnal Kedokteran Brawijaya Vol 31, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.545 KB) | DOI: 10.21776/ub.jkb.2020.031.01.12

Abstract

Fetal gender might affect the iron status of newborns. Hepcidin has an important role in the process of maternofetal iron transport. This study aims to compare the newborn iron status and the umbilical cord hepcidin levels between male and female gender. A cross-sectional study was conducted with subjects of 84 clinically healthy newborns. Written informed consent and ethical approval were carried out. Newborn iron status observed included (i) hematologic markers (RBC count, Hb, hematocrit, mean corpuscular volume (MCV) and red cell distribution width), and (ii) biochemical markers (serum iron (SI), serum ferritin (SF), soluble transferrin receptor (sTfR) and cord blood hepcidin). Hematologic markers were checked using Sysmex, XN-1000, while Hepcidin and sTfR were using ELISA. Serum iron was checked using IRON Flex®. Statistical analysis was tested with the independent t-test and the Mann-Whitney. All newborns and their mothers were in normal condition. The mean sTfR levels of newborns were significantly higher in the male group than females (38.3±9.06 vs. 34.3±8.16 nmol/L) with p=0.033. High sTfR levels reflect a low iron status. In conclusion, fetal gender differences influence the iron status of newborns, and male newborns have a potentially higher iron deficiency.
Fetal Growth Cut-Off Point To Predict Neonatal Outcome In Pregnancy With Normal And Deficient Vitamin D Levels: Intergrowth-21, World Health Organization Fetal Growth Curve, And Hadlock’s Estimated Fetal Weight Dewantiningrum, Julian; Kristanto, Herman; Pudjonarko, Dwi; Mexitalia, Maria; Ediati, Annastasia; Soejoenoes, Ariawan; Hadisaputro, Suharyo
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i2.877

Abstract

Purpose : Analyze the cut-off point of fetal growth based on the Intergrowth-21, World Health Organization (WHO), and Hadlock’s estimated fetal weight (EFW) in pregnant women with normal or deficient vitamin D levels to predict neonatal outcomes. Method: This cross sectional study to develop a diagnostic test, included 120 of pregnant women who completed follow up until children aged 2 years, divided into normal and deficient vitamin D group. Ultrasound and maternal vitamin D level examined during the second trimester of pregnancy. EFW was calculated using Hadlock’s formula and plotted on the Intergrowth-21 and WHO curves. The reference standards were the neonatal outcome, LBW, stunting, and neurocognitive impairment. Significant odds ratio (OR) value and area under the curve (AUC) of 0.6 are used to determine the cut-off point to be used. Result: Fetal growth curve was based on the WHO at the 5th percentile to predict LBW to have an AUC of 0.6 and OR of 6, 95% confidence interval (CI) of 1.36–26.45. The AUC for predicting LBW based on Intergrowth and Hadlock were 0.45 and OR not significant. As well as the AUC estimated stunting based on Hadlock, the Intergrowth-21 and the WHO fetal growth curves is <0.6 with OR not statistically significant. The AUC predicted neurocognitive impairment based on WHO’s chart was 0.6 but OR not statistically significant. Conclusion: The WHO fetal growth curve can be used to predict LBW. The cut-off point of the fetal growth curve and which percentile is determined by the neonatal outcome.
Co-Authors Ag Soemantri Annastasia Ediati Dwi Pudjonarko Fauziah, Nur Alfi Ginting, Erwin Herman Kristanto Hidajati, Kamilah Julian Dewantiningrum Maria Mexitalia Milhan Milhan, Milhan Qodri Santosa, Qodri Risanto Siswosudarmo Shinta Prawitasari Soeharyo Hadisaputro Suharyo Hadisaputro Umar Malinta