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All Journal Jurnal Anestesiologi Indonesia MEDIA MEDIKA INDONESIANA International Journal of Science and Engineering (IJSE) JURNAL GIZI INDONESIA Nurse Media Journal of Nursing Jurnal Kedokteran Diponegoro Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Interest : Jurnal Ilmu Kesehatan Jurnal Keperawatan dan Kesehatan Masyarakat CENDEKIA UTAMA Jurnal Epidemiologi Kesehatan Komunitas Medica Hospitalia Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Diponegoro International Medical Journal (DIMJ) Narra J JHeS (Journal of Health Studies) Neurona Jurnal Bidan Cerdas
Dwi Pudjonarko
Fakultas Kedokteran Universitas Diponegoro
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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HUBUNGAN LOKASI LESI STROKE NON-HEMORAGIK DENGAN TINGKAT DEPRESI PASCA STROKE (STUDI KASUS DI POLI SARAF RSUP DR. KARIADI SEMARANG) Bagaskoro, Yoseph Cahyo; Pudjonarko, Dwi
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 6, No 2 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.802 KB) | DOI: 10.14710/dmj.v6i2.18650

Abstract

Latar Belakang:Dari seluruh penderita stroke di dunia yang terdata, sekitar 80% merupakan jenis stroke non-hemoragik. Terdapat beberapa faktor yang menentukan prognosis dari stroke non-hemoragik, salah satunya ialah lokasi lesi (lokasi infark).Depresi seringkali dikaitkan dengan penyakit kronik seperti stroke. Depresi yang berkaitan dengan stroke disebut sebagai depresi pasca stroke. Depresi pasca stroke dapat memperparah kondisi pasien stroke sehingga memperlambat proses pemulihan. Prevalensi yang paling tinggi terdapat sekitar 3-6 bulan pasca stroke dan tetap tinggi sampai 1-3 tahun kemudian. Lokasi lesi diduga mempengaruhi tingkat depresi pasca stroke.Salah satu pemeriksaan depresi adalah dengan HDRS dimana pemeriksaan ini merupakan skrining penilaian depresi yang paling sering dipakai. HDRS ini sangat mudah dan relatif cepat.Tujuan:Untuk membuktikan adanya hubungan antaralokasi lesi stroke non-hemoragik dengan tingkat depresi pasca stroke.Metode:Penelitian ini merupakan penelitian observasional analitik dengan rancangan belah lintang. Penelitian ini dilaksanakan di Poliklinik Saraf RSUP Dr Kariadi Semarang. Subyek penelitian sebanyak 22 pasien dengan teknik consecutive sampling. Data yang digunakan merupakan data primer yaitu hasil pemeriksaan HDRS dan data sekunder yaitu rekam medis dari April 2016 sampai Agustus 2016. Uji statistik menggunakan uji Chi-square.Hasil:  Terdapat 22 pasien yang terdiri dari 11 orang yang memiliki lesi di hemisfer kiri dan 11 orang memiliki lesi di hemisfer kanan. Tidak didapatkan hubungan antara lokasi lesi stroke non-hemoragik dengan tingkat depresi pasca stroke (p 0,387).Kesimpulan:Tidak terdapat hubungan antara lokasi lesi stroke non-hemoragik dengan tingkat depresi pasca stroke.
KORELASI LOKASI PERDARAHAN INTRASEREBRAL DENGAN OUTCOME PASIEN STROKE HEMORAGIK Pradesta, Rizki Rudwi; Sukmaningtyas, Hermina; Pudjonarko, Dwi
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 6, No 2 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.692 KB) | DOI: 10.14710/dmj.v6i2.18629

Abstract

Latar belakang Angka kejadian stroke meningkat tajam beberapa tahun kebelakang dan Indonesia menjadi negara dengan jumlah penderita stroke terbanyak di Asia. Stroke hemoragik intraserebral merupakan jenis kedua terbanyak dari pasien stroke setelah stroke iskemik. Outcome stroke dipengaruhi oleh banyak faktor antara lain GCS, volume perdarahan, lokasi perdarahan, perluasan intraventrikuler, dan adanya peningkatan waktu pembekuan darah. Lokasi perdarahan merupakan faktor yang berpengaruh kuat untuk memprediksi kefatalan kasus, letak lokasi perdarahan yang bervariasi menyebabkan lokasi perdarahan bisa dijadikan pembeda untuk menentukan tingkat keparahan prognosis pasien stroke hemoragik. Penilaian outcome  stroke dapat dinilai dengan menggunakan Barthel Index karena realibilitasnya yang cukup tinggi yaitu 0,95 dan dapat dilakukan dalam waktu singkatTujuan Mengetahui korelasi lokasi perdarahan intraserebral dengan outcome pasien stroke hemoragik.Metode penelitian ini merupakan penelitian Observasional Analitik dengan metode Belah Lintang. Subjek merupakan pasien yang terdaftar sebagai pasien Stroke Hemoragik di RSUP Dr. Kariadi Semarang tahun 2015-2016. Data yang dikumpulkan adalah data sekunder berupa skala nominal yang ditentukan dari hasil CT Scan lokasi perdarahan pasien dan data ordinal yang didapatkan dari hasil penilaian kuesioner Barthel Index. Uji statistik menggunakan uji korelasi Chi Square.Hasil Tidak terdapat korelasi antara lokasi perdarahan dengan outcome  pasien stroke hemoragik yang dihitung menggunakan Barthel Index dengan nilai p= 0.665 (bermakna bila p < 0,05).Kesimpulan Tidak terdapat korelasi antara lokasi perdarahan dengan outcome  pasien stroke hemoragik yang dihitung menggunakan Barthel Index pada penelitian kali ini.
PENGARUH RANITIDIN TERHADAP DEGENERASI AKSON AKIBAT NEUROPATI NERVUS OPTIK (STUDI PADA TIKUS WISTAR DENGAN INTOKSIKASI METANOL AKUT) Armatussolikha, Herna Rizkia; Pudjonarko, Dwi
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 1 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (933.892 KB) | DOI: 10.14710/dmj.v7i1.19373

Abstract

Latar Belakang: Kejadian keracunan minuman keras (Miras) oplosan di Indonesia menunjukkan angka yang cukup tinggi. Salah satu zat yang sering digunakan dalam minuman oplosan tersebut adalah metanol. Metanol sebenarnya tidak bersifat toksik, namun hasil metabolisme metanol bersifat toksik bagi tubuh. Salah satu dampak dari toksisitas metanol adalah masalah pada nervus optik yang dapat berakhir dengan kebutaan. Salah satu cara untuk menangani efek toksisitas metanol tersebut adalah dengan menggunakan ranitidin sebagai antidotum. Namun, pengaruh pemberian ranitidin terhadap derajat degenerasi akson nervus optik pada tikus wistar yang diintoksikasi metanol akut masih belum dilakukan penelitian lebih lanjut. Tujuan: Mengetahui pengaruh pemberian ranitidin terhadap degenerasi akson akibat neuropati nervus optik pada tikus Wistar dengan intoksikasi metanol akut.Metode: Penelitian eksperimental dengan rancangan penelitian post test only group design. Penelitian ini menggunakan 3 (tiga) kelompok yang terdiri atas: kelompok perlakuan, kelompok kontrol positif, dan kelompok kontrol negatif. Untuk analisis data digunakan uji Saphiro-wilk, Levene’s test,One Way Anova dan Post Hoc Benforroni.Hasil: Tidak terdapat perbedaan yang bermakna antara kelompok yang diintoksikasi dengan metanol saja (kelompok kontrol positif) dengan kelompok yang diintoksikasi dengan metanol yang kemudian diberikan ranitidine (kelompok perlakuan) setelah 30 menit (p = 0.298) dan terdapat perbedaan yang bermakna antara kelompok kontrol negatif yang tidak diberi metanol maupun ranitidin dengan kelompok kontrol positif (p= 0.001).Kesimpulan: Ranitidin dosis 30 mg/kgbb yang diberikan 30 menit setelah intoksikasi metanol akut tidak memiliki pengaruh yang signifikan terhadap penurunan kejadian degenerasi akson akibat neuropati nervus optik pada tikus wistar yang diintoksikasi metanol akut.
The Effect of “SELF-HELP Packages” on Post Stroke Depression among Ischemic Stroke Survivors Handayani, Fitria; Setyowati, Setyowati; Pudjonarko, Dwi; Sawitri, Dian Ratna
Nurse Media Journal of Nursing Vol 10, No 3 (2020): (December 2020)
Publisher : Department of Nursing, Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/nmjn.v10i3.31014

Abstract

Background: There are several factors that contribute to Post Stroke Depression (PSD). Since a single intervention is proven ineffective to deal with PSD, an intervention which includes biological, psychological, social, and spiritual aspects (“SELF-HELP Packages”), therefore, needs to be established.Purpose: The purpose of the study was to investigate the effect of “SELF HELP Packages” intervention on PSD among ischemic stroke survivors after three months from onset and its effect after confounding variables were controlled.Methods: This study was a pre and post quasi-experiment with a control group involving 34 ischemic stroke survivors each group. The inclusion criteria were survivors after three months from ischemic stroke, no aphasia, having a good hearing, and having Mini Mental Status Examination (MMSE) score of ≥ 22. GRID-HAMD 17, Multidimensional Scale of Perceived Social Support (MSPSS), and Barthel-Index were used to measure PSD, social support, and functional status respectively. “SELF-HELP Packages” intervention was delivered in three sessions, namely information delivery, discussion and activity. Statistical analyses were conducted using McNemar test, Chi-square and logistic regression.Results: The result showed that “SELF-HELP Packages” considerably decreased PSD in the intervention group (p=0.004). There were also significant differences in PSD after the intervention between two groups (p=0.008). Logistic regression showed that ‘SELF-HELP Package” had no effect on PSD when other confounding variables were controlled (p=0.075, OR=0.288, 95% CI 0.073 – 1.135).Conclusion: SELF-HELP Packages” should be applied in providing the nursing intervention among stroke ischemic survivors in clinical setting. A longer period of time for the intervention is also recommended for the next study in order to obtain a more robust result.   
Association of Functional Outcome and Post Stroke Depression among Ischemic Stroke Patients after Three Months Onset: A Preliminary Study Handayani, Fitria; Setyowati, Setyowati; Pudjonarko, Dwi; Sawitri, Dian Ratna; Sakti, Hastaning; Suparyatmo, J.B; Adi, Matius Sakundarno
Jurnal Keperawatan Soedirman Vol 14, No 1 (2019)
Publisher : Jurusan Keperawatan FIKES UNSOED

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2019.14.1.888

Abstract

Background The Post Stroke Depression (PSD) prevalence of stroke survivor after three months onset was ranged from 17% to 37%. Depression led to fatigue, low quality of life, severe morbidity, and mortality.  Functional Outcome influence depression on stroke survivor.  However, correlation between functional state level and depression among stroke survivor after three months onset has not been established. ObjectiveThis study was aimed to investigate the correlation of executive functional outcome and PSD among stroke survivor after three months onset. MethodThis study was a correlation study. The participants were 44 stroke ischemic patients after three months onset. Participants were recruited in an outpatient unit. PSD was measured using The GRID-Hamilton Rating Scale for Depression 17 (GRID-HAMD 17) and Functional Outcome was measured using Barthel Index (BI). The reliability of GRID-HAMD 17 was .776.  Both instruments were conducted on backward translation in to bahasa. Data was examined using simple linier regression analyses.  The ethical approval was obtained from the Ethical Research Committee of the Medical Faculty Diponegoro University and Tugurejo Semarang Hospital. ResultsThe presence of PSD were 56.82. The median of HAMD-GRID-17 was 10.38 ± 7.58, and Barthel Index was 69.56 ± 21.69.  The Barthel Index showed positive correlation with HAMD-GRID-17 (?= -.41 ?=.006). The Functional Outcome determined PSD as much as 16.8 %. ConclusionModerate association demonstrated the correlation between Functional Outcome and PSD. Nursing intervention should consider these two variables for an optimum quality of life among stroke survivors.  
PENGARUH AKUPRESUR DAN SHAKER EXERCISE TERHADAP KEMAMPUAN MENELAN PASIEN STROKE AKUT DENGAN DISFAGIA Dewi Siyamti; Dwi Pudjonarko; Mardiyono Mardiyono
Jurnal Keperawatan dan Kesehatan Masyarakat Cendekia Utama Vol 8, No 2 (Oktober 2019) : Jurnal Keperawatan dan Kesehatan Masyarakat Cendekia Utama
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (511.348 KB) | DOI: 10.31596/jcu.v8i2.413

Abstract

Disfagia merupakan permasalahan pasien stroke akut yang disebabkan oleh gangguan saraf dan terjadi pada pasien usia dewasa dan lanjut. Hal ini berdampak pada risiko pneumonia, malnutrisi, dehidrasi dan menurunnya kualitas hidup. Akupresur merupakan terapi dengan stimulasi pada acupoint dan memberikan manfaat terhadap proses penyembuhan penyakit. Shaker exercise merupakan latihan menelan yangbanyak digunakan pada pasien disfagia. Penelitian ini bertujuan untuk mengetahui adanya pengaruh akupresur dan shaker exercise terhadapkemampuan menelan pasien stroke akut dengan disfagia. Penelitian ini menggunakan desain eksperimen pretest-postest dengan kelompok kontrol. Sampel dipilih menggunakan stratified random sampling dengan jumlah 17 responden masing-masing di kelompok kontrol dan intervensi yang disesuaikan dengan kriteria inklusi dan ekslusi. Pada kelompok intervensi diberikan oral care, pengaturan posisi, akupresur dan shaker exercise selama 5 hari dalam satu minggu, akupresur satu kali sehari dan shaker exercise tiga kali sehari. Pada kelompok kontrol diberikan oral care dan pengaturan posisi tiga kali sehari selama 5 hari.Penilaian kemampuan menelan dilakukan menggunakan Gugging Swallowing Severity Scale (GUSS) sebelum dan setelah intervensi selama dua minggu. Data dianalisa dengan uji Friedman. Hasil penelitian menunjukkan nilai p<0,05 pada minggu kedua evaluasi. Kemampuan menelan pada kelompok intervensi meningkat 4,69 poin  sedangkan pada kelompok kontrol meningkat 2,13 poin. Akupresur dan Shaker exercise pada kelompok intervensi terbukti meningkatkan kemampuan menelan pasien stroke akut dengan disfagia dan peningkatan kemampuan menelan pasien dapat dilihat pada minggu kedua. Intervensi akupresur dan Shaker exercise dapat digunakan sebagi alternatif tindakan dalam asuhan keperawatan untuk pasien yang mengalami disfagia. Penelitian selanjutnya diharapkan dapat menambah jumlah titik akupresur dan lama waktu intervensi Kata Kunci: akupresur, disfagia, shaker exercise, stroke
Pain Stimulated by Electric Foot Shock to Liver and Spleen Microscopic Immunological Response Features (BALB/c Mice Experimental Study) Dwi Pudjonarko; M Naharuddin Jenie; Udadi Sadhana
MEDIA MEDIKA INDONESIANA 2010:MMI VOLUME 44 ISSUE 1 YEAR 2010
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (261.17 KB)

Abstract

Background: Pain affects immune system by decreasing type I-immune response that might be seen on microscopic features of liver and spleen. The objective of the study is to prove the effect of pain to immune response that confirmed by liver microabscess formation, hepatocytes destruction and spleen multinucleated giant cells of Balb/c mice suffered from pain.Method: This study adapts Laboratory Experimental and Post-Test Only Control Group Design. The samples were 12 female BALB/c mice (average weight 21.88 (SD=1.75) grams and divided into two groups. The control group (C) received no other additional treatment. The Pain (P) group received pain stimulated by Electric Foot Shock (EFS) 1-3 mA at day 12th to 21st. All groups were intravenously injected with 104 live L. monocytogenes at day 21st and sacrificed at day 26th by chloroform anaesthesia. Then, liver microabscess formation, hepatocytes destruction and spleen multinucleated giant cells were counted. Data were analyzed by independent t-test (significant if p<0.05).Result: There were significant differences in the liver microabscess formation, hepatocytes destruction and spleen multinucleated giant cells (p<0.05) between the groups. The number of liver microabscess formation and hepatocytes destruction in the P group were higher than C group. The number of spleen multinucleated giant cells in the P group were lower than C group. Conclusion: Pain has an immunosuppressive effect not only on high liver microabscess formation and hepatocytes destruction, but also low spleen multinucleated giant cells.ABSTRAKPengaruh nyeri yang distimulasi electric foot shock terhadap gambaran mikroskopis respon imunologis di hepar dan lien. (Studi eksperimental pada mencit Balb/c).Latar belakang: Nyeri dapat mempengaruhi imunitas tubuh dengan menurunkan produksi sitokin tipe 1 yang kemungkinan akan mempengaruhi gambaran mikroskopis respon imunologis baik di hepar maupun lien. Penelitian ini bertujuan untuk membuktikan penurunan imunitas seluler yang dilihat dari mikroabses dan kerusakan hepatosit pada hepar serta sel datia lien mencit BALB/c yang mendapatkan stimulasi nyeri dengan electric foot shock (EFS).Metode: Penelitian ini merupakan penelitian eksperimental laboratorik, dengan pendekatan the post test–only control group design yang menggunakan 12 ekor mencit betina strain BALB/c, umur 6-8 minggu dan rerata barat badan 21,88 (SD=1,75) gram. Sampel dibagi dalam 2 kelompok dan mendapatkan makanan standar. Pada kelompok Kontrol (K), mencit tidak mendapatkan perlakuan, sedangkan kelompok Nyeri (N), mencit mendapat sensasi nyeri menggunakan EFS mulai hari ke-12 sampai 21. Pada hari ke-21, semua mencit disuntik 104 listeria monocytogenes hidup iv. Dilakukan terminasi mencit pada hari ke-26 untuk dilakukan penghitungan mikroabses dan kerusakan hepatosit pada hepar serta sel datia lien. Dilakukan uji beda antar kelompok perlakuan dengan independent t-test. Perbedaan dinyatakan bermakna bila didapatkan nilai p<0,05.Hasil: Terdapat perbedaan yang bermakna pada jumlah mikroabses dan kerusakan hepatosit pada hepar serta sel datia lien pada mencit yang distimulasi nyeri dengan EFS dibandingkan kontrol (p<0,05). Stimulasi nyeri dengan EFS menyebabkan mikroabses dan kerusakan hepatosit pada hepar lebih tinggi terhadap kontrol, sedangkan sel datia pada lien jumlahnya lebih rendah bila dibandingkan kontrol
The role of fluoxetine on macrophage function in chronic pain (Experimental study in Balb/c mice) Dwi Pudjonarko; Edi Dharmana; OS Hartanto
International Journal of Science and Engineering Vol 9, No 1 (2015)
Publisher : Chemical Engineering Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (651.319 KB) | DOI: 10.12777/ijse.9.1.27-33

Abstract

Chronic pain raises stress conditions such as depression that can lower the cellular immunity. Fluoxetine is an antidepressant  used as an adjuvant in pain management but no one has been linked it with the body immune system. The objectives of this research were to proof the benefits of fluoxetine in  preventing degradation of macrophage function in chronic pain by measuring the macrophage phagocytic index , macrophage NO levels and the liver bacterial count in BALB/c mice infected with Listeria Monocytogenes.A Post Test - Only Control Group Design was conducted using 28 male mice strain BALB /c, age 8-10 weeks. The control group (C), mice got the same standard feed as the other groups. Chronic pain group (P), mice were injected with 20μL intraplantar CFA on day-1. Pain + fluoxetine early group (PFE) were treated with P + fluoxetine 5 mg / kg ip day-1, the 4th, the 7th and the 10th, while the Pain + fluoxetine late group (PFL) were treated with P + fluoxetine 5 mg / kg ip on day 7th and 10th. All mice were injected with 104 live Listeria monocytogenes iv on day 8th. Termination was performed on day 13th. Differences within groups  were analyzed using  One-way ANOVA and Kruskall Wallis, whereas the correlation of variables were analyzed using  Pearson's product moment. The experimental results showed that The macrophage phagocytic index and NO macrophage level (pg/mL) in PFE group(2,24±1,013; 0,24±0,239) was higher than than P group (1,68±0,920; 0,21±0,263) and there was no different in the macrophage phagocytic index of PFE group compared to C group (p=0,583; p=0,805). In PFL group (4,32±1,459; 0,54±0,294) the macrophage phagocytic index as well as NO macrophage level (pg/mL) was higher than P group (1,68±0,920; 0,21±0,263) with p=0,002; p=0,017. P group Bacterial count (log cfu/gram) (2,30±0,849) was significantly higher than C group(1,15±0,223) (p=0,007), while PFE group bacterial count (1,96±0,653) and PFL group bacterial count (1,84±0,403) compared to C (1,15± 0,223) was not significantly different (p=0,093; p=0,220). Correlation found between macrophage phagocytic index and macrophage NO (r=0,515, p=0,005).Macrophage phagocytic index and macrophage NO showed no correlation with bacterial count (r=-0,051, p=0,798; r=-0,071, p=0,719).It can be concluded that fluoxetine significantly incerases macrophage phagocytosis index and macrophages NO level in mice with chronic pain,  on the other hand fluoxetine decreases liver bacterial count . There is a positive correlation between macrophage phagocytosis index and macrophages NO level, while no correlation observed  among two variables with mice liver bacterial count in chronic pain.
Correlation of Folic Intake and Internal Carotid Artery Intima-Media Thickness Changes In Post Ischemic Stroke Patients Dodik Tugasworo; Dwi Pudjonarko; Latifah Latifah
International Journal of Science and Engineering Vol 8, No 2 (2015)
Publisher : Chemical Engineering Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.464 KB) | DOI: 10.12777/ijse.8.2.159-166

Abstract

The thickness of the carotid artery intima media / intima-media thickness (IMT) is one of atherosclerosis markers. Atherosclerosis is one of the causes of ischemic stroke. Some studies suggest that low folate intake is predicted to affect the atherosclerotic process, but this remains controversial. Our objective is to analyze the relationship between folate intake with changes in the internal carotid artery IMT after ischemic stroke patients.The study is one group pretest posttest design with 72 post ischemic stroke subjects from neurology polyclinic of Kariadi Hospital, from June to December 2013. Folate intake was measured by Food Frequency Questionnaire and the internal carotid artery IMT by duplex ultrasonography. Measurements were taken at two periods with 6 months interval. Other factors that affect atherosclerosis consisting of age, obesity, hypertension, dyslipidemia, diabetes mellitus. The analysis in this study using Spearman correlation, chi-square and logistic regression. Resultwas significant if the p value were <0.05.There were 44 male subjects (61.1%) and 28 female subjects (38.9%). The mean age was 61.6 (SD = 7.99) years. The mean intake of folate was 178.10 (SD = 38.875) mg / day. Median serum folic acid level 8.43 (4.96 to 55.01) NML / L. The mean change in ICA IMT was 0.10 (SD = 0.156) mm. Folate intake was not correlated with serum levels of folic acid. Serum folic acid levels are not correlated with changes in the internal carotid artery IMT. There was correlation between the risk factors of age, BMI, hypertension, diabetes and dyslipidemia with changes in the internal carotid artery IMT.
Gaya Hidup yang Berpengaruh terhadap Kejadian Stroke Iskemik pada Usia Kurang dari 45 Tahun (Studi Pada BLUD RSUD Cut Nyak Dhien Meulaboh Kabupaten Aceh Barat Provinsi Aceh) Arif Iskandar; Suharyo Hadisaputro; Dwi Pudjonarko; Suhartono Suhartono; Dodik Tugasworo Pramukarso
Jurnal Epidemiologi Kesehatan Komunitas Vol 3, No 2: Agustus 2018
Publisher : Master of Epidemiology, School of Postgraduate Studies, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (20637.043 KB) | DOI: 10.14710/jekk.v3i2.4023

Abstract

Background: Ischemic stroke that occurs at the age of less than 45 years accounts for about 5 until 10 percent of the total stroke. This is influenced by changes in the life-style of modern society, such as changes in the pattern of food consumption, lazy to move, and smoking habits. This study aims to examine the effect of life-style on ischemic stroke at less than 45 years old people.Method: This study uses observational method with design of cases and controls. The samples are 86 observations consisting of 43 cases and 43 controls. Cases are patients with ischemic stroke less than 45 years of age and controls are non-stroke patients of neurology who are less than 45 years old.Results: The results show that the habit of consuming food containing high fat (p=0,032, OR=3,744, 95% CI=1,124-12,468) and smoking habit (p=0,019, OR=3.859, 95% CI=1,250-11,911) affect the occurrence of ischemic stroke at age less than 45 years. However, the habit of consuming red meat, consuming foods containing high salt, consuming drugs, and lack of physical activity do not affect the occurrence of ischemic stroke at age less than 45 years.Conclusion: The habits of consuming food containing high fat and smoking affect theoccurrence of ischemic stroke at age less than 45 years after hypertension, heart disease, and diabetes mellitus are controlled.
Co-Authors Amin Husni Ani Margawati Annastasia Ediati Aria Nurahman Hendra Kusuma Arif Iskandar Arinta Puspita Wati, Arinta Puspita Aris Catur Bintoro Arlina, Yani Armatussolikha, Herna Rizkia Bagaskoro, Yoseph Cahyo Budisulistyo, Trianggoro Darmawati Ayu Indraswari Dewi Siyamti Diah Pasmanasari, Elta Dian Ratna Sawitri Dodik Pramukarso Dodik Tugasworo Dodik Tugasworo Dodik Tugasworo Pramukarso Edi Dharmana Endang Mahati Fauzi, Muhammad Iqbal Fitria Handayani Fitria Handayani Handayani Fitria Handayani Handayani Handayani, Fitria Hardhono Susanto Hari Peni Julianti Hartono, Jimmy Eko Budi Hassa, Nazwan Hastaning Sakti Herinawati, Herinawati Herman Kristanto Hermawan Istiadi Hermina Sukmaningtyas Ignatius Riwanto, Ignatius Julian Dewantiningrum Koestoer, Clara Krishanti Kusman Ibrahim Latifah Latifah Lestari, Lis Mukti Lis Mukti Lestari M Naharuddin Jenie Mardiyono, Mardiyono Maria Mexitalia Martha Irene Kartasurya Mateus Sakundarno Adi, Mateus Sakundarno Meidiana Dwidiyanti Meutia, Yurida Binta Muis, Siti F. Murbawani, Etisa A. Noegroho, Aji Nugraha, Laksmana AK. Nurahman Hendra Kusuma, Aria OS Hartanto Pangesti, Adelia Pradesta, Rizki Rudwi Pramukarso, Dodik T. Pranoto, Stephano Rahmawati, Maria Belladonna Ramadhany, Ghifarie A. Respati, Danendra RP. Retnaningsih Retnaningsih Rifky Ismail Satrio Adi Wicaksono Setyowati Setyowati Soejoenoes, Ariawan Sri Achadi Nugraheni Stephani Nesya Renamastika Subagio, Hertanto W. Suhartono, Suhartono Suharyo Hadisaputro Suharyo Hadisaputro Sunjata, Winda Putri Suparyatmo, J.B Suryawati, Herlina Tjandra, Kevin C. Udadi Sadhana, Udadi Untung Sujianto Vania Pangestika Purwaningrum