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All Journal Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Pengabdian Pada Masyarakat Journal of Innovative and Creativity Journal of Medical Laboratory in Infectious and Degenerative Diseases
Setyaningrum, Lindawati
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Pengolahan MBAH KOPI (liMBAH PAdat KOtoran saPI) sebagai Pupuk Kandang pada Kelompok Petani-Peternak Sejahtera di Desa Cangkring, Prajekan-Bondowoso Usman, Mohammad Rofik; Setyaningrum, Lindawati; Ivana, Nanda Letitia; Diana, Ilvid; Yanti, Eka Fitri
Jurnal Pengabdian Pada Masyarakat Vol 9 No 4 (2024): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/jppm.v9i4.999

Abstract

Limbah kotoran sapi adalah sumberdaya peternak yang belum termanfaatkan. Peternak umumnya mengatasi limbah kotoran sapi dengan cara membuang ke sungai atau membakar limbah kotoran sapi. Dua hal tersebut dapat menimbulkan permasalahan lingkungan yang kompleks, dengan demikian diperlukan solusi untuk menangani hal tersebut yaitu dengan cara mengolah limbah kotoran sapi menjadi barang yang memiliki manfaat. Salah satu solusinya yaitu mengolah limbah kotoran sapi menjadi pupuk kandang menggunakan bahan Ni35 dimana bahan ini dapat mempercepat dekomposisi limbah padat kotoran sapi menjadi pupuk kandang. Metode yang digunakan dalam pengabdian ini dimulai dari penyuluhan, pelatihan, monitoring, dan evaluasi pelaksanaan produksi pupuk dan hasil uji pada tanaman kangkung dan cabai. Hasil pelaksanaan pengabdian menunjukkan bahwa peserta sangat antusias dalam mengikuti serangkaian kegiatan, serta dapat memproduksi pupuk kandang dengan kemampuan yang dapat bersaing dengan pupuk kandang konveksional/komersil. Cow manure is an underutilized resource among farmers. Generally, farmers address cow manure waste by discarding it into rivers or burning it. Both practices can lead to complex environmental problems. Thus, solutions are needed to manage this issue by transforming cow manure into valuable products. One solution involves processing cow manure into organic fertilizer using a substance called Ni35, which accelerates the decomposition of solid cow manure into usable compost. The method used in this community engagement project includes outreach, training, and monitoring, along with evaluating the production process and testing the fertilizer's effects on plants such as water spinach and chili. The results of this initiative show that participants were highly enthusiastic about the activities and successfully produced compost with competitive quality comparable to conventional commercial fertilizers.
Pengaruh Pelarut Metanol dan Etanol Terhadap Kadar Flavonoid Total Ekstrak Kulit Pohon Waru (Hibiscus tiliaceus L.) Putri, Astrid Kusuma; Susanto, Lunardhi; Iswardjono, Deva Oktavy American; Rahayu, Asti; Setyaningrum, Lindawati
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 5, No 2 (2024): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v5i2.17465

Abstract

Sea hibiscus (Hibiscus tiliaceus L.) is one of the plants in Indonesia that is empirically used as a traditional medicine. The study aims to determine the total flavonoid content of methanol and ethanol extracts from the sea hibiscus tree bark using UV-Vis spectrophotometry. Phytochemical screening of flavonoids is done using concentrated magnesium and hydrochloric acid (HCl). Total flavonoid levels are determined using the AlCl3 method specified in the QE (Quercetin equivalent). The phase of the research method includes preparation of methanol extract and ethanol extracts, phytochemical screening of flavonoid content, quantitative analysis of the flavonoid content (determination of the maximum wavelength (λmax) of quercetin, standard curve preparations of quercetin, and determination of flavonoid contents in methanol extract and ethanol extract), data management and analysis. Phytochemical screening showed methanol extracts and ethanol extract of the Sea Hibiscus tree bark showed positive contain flavonoids. Quantitative tests using UV-Vis spectrophotometry measured at 441 nm wavelengths showed that the concentration of flavonoid compounds in the Sea Hibiscus tree bark methanol extract was 0.109 %b/b, and the concentrations of flavonoids in the ethanol extracts were 0.096 %b/b.
Evaluation of Traditional Medicine Label Compliance Based on CPOTB: Post-Market Surveillance in the Working Area of BPOM Kediri Setyaningrum, Lindawati; Nirwana, Fenti Indah; Agustina, Dian Reny
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.6852

Abstract

Introduction. Post-market surveillance of traditional medicines is an essential regulatory activity to ensure product quality, safety, and the accuracy of information provided to consumers. One critical component of such surveillance is evaluating the compliance of product labels with applicable regulatory requirements. Aim. This study aimed to assess the conformity of traditional medicine labeling with the implementation of Good Manufacturing Practices for Traditional Medicines (CPOTB) within the working area of BPOM Kediri as part of a risk-based post-market regulatory strategy. Method. This applied observational study employed a descriptive cross-sectional design. Data were obtained from post-market surveillance activities through sampling of 30 traditional medicine products collected from pharmacies, herbal shops, modern retailers, and traditional markets within the BPOM Kediri jurisdiction during 2023–2025. Label conformity was evaluated using a CPOTB-based checklist in accordance with BPOM Regulation No. 25 of 2021. Data were analyzed descriptively to identify compliance profiles and dominant non-compliance categories. Result. A total of 30 findings of non-compliance were identified from 30 product samples, demonstrating an increasing trend over the three-year period. The most frequent non-compliance indicators were excessive or misleading claims (30.0%), absence of batch or lot numbers (26.7%), and absence or misuse of marketing authorization numbers (23.3%). These findings indicate potential risks related to consumer protection, product traceability, and regulatory assurance. Conclusion. Systematic evaluation of traditional medicine labeling through post-market surveillance serves as a strategic regulatory instrument to strengthen oversight, enhance consumer protection, and support effective implementation of CPOTB in Indonesia.
In-Silico Study Of Bioactive Compounds In Bawang Dayak (Eleutherine palmifolia (L) Merr.) Bulbs On The Main Protease Receptor Of COVID-19 (6LU7) As A Candidate For SARS-CoV-2 Antivirus Drug Septiana, Ulfa Dwi; Wulandari, Septyaningtyas Eka; Kamalia, Nabila; Hezni, Tiara Anjelina; Usman, Mohammad Rofik; Setyaningrum, Lindawati
Journal of Medical Laboratory in Infectious and Degenerative Diseases Vol. 3 No. 2 (2025): Desember
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jmid.v3i2.40

Abstract

: The COVID-19 viral disease is a new name given by the World Health Organization (WHO) to patients with the novel COVID-19 virus infection which was first reported from the city of Wuhan, China at the end of 2019. The COVID-19 pandemic is still a major problem in the world health. One antiviral regimen that is widely used to treat moderate to severe Covid- 19 patients is favipiravir. Many studies discuss alternative antiviral therapy for COVID-19 patients from active compounds contained in plants. One of the medicinal plants that has an antiviral effect on CoV-2 is Dayak onion (Eleutherine Palmifolia (L.) Merr). Consuming herbal plants can increase the body's immunity as the main key in preventing the Sars-Cov-2 virus. Purpose: This research aims to determine the effect of anchoring the active compound of Dayak onion bulbs on the growth of the corona virus on the main protease receptor for Covid 19 (6LU7). Methods: This type of research uses a molecular docking research method which consists of docking validation stages, a docking process and continues with docking visualization using Discovery Studio Visualizer and PyRx combined with Autodocktool Results: The results of the molecular docking simulation show that the Lysine sulfate compound has the lowest binding affinity value compared to Favipiravir, namely -4.75 kcal/mol with a Ki value of 96.41 μM and has the same interaction as the positive control ligand on the hydrophobic bond of MET A:165
Co-Authors Agustina, Dian Reny Diana, Ilvid Eka Fitri Yanti, Eka Fitri Hezni, Tiara Anjelina Iswardjono, Deva Oktavy American Ivana, Nanda Letitia Kamalia, Nabila Mohammad Rofik Usman Nirwana, Fenti Indah Putri, Astrid Kusuma Rahayu, Asti Septiana, Ulfa Dwi Susanto, Lunardhi Wulandari, Septyaningtyas Eka