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All Journal JTSL (Jurnal Tanah dan Sumberdaya Lahan) Jurnal Biologi Tropis
Febryani, Noor
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Immunology & microbiology

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PEMANFAATAN PSEUDOMONAS AERUGINOSA UNTUK PENINGKATAN KUALITAS KOMPOS KERTAS DAN PENDEGRADASI LOGAM BERAT Fitria, Anita Dwy; Yuliyani, Leny; Febryani, Noor; Alfath, Jusan Zaki; Sundawa, Rendi; Oktavia, Revina
Jurnal Tanah dan Sumberdaya Lahan Vol. 12 No. 2 (2025)
Publisher : Departemen Tanah, Fakultas Pertanian, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtsl.2025.012.2.5

Abstract

Improving the quality of compost paper is important to increase the availability of nutrients and reduce heavy metals. The quality of compost paper can be improved by using Pseudomonas aeruginosa bacteria, which can help mineralize nutrients and break down or convert heavy metals into less harmful forms. This study used a completely randomized design with five treatments in different concentrations of Pseudomonas aeruginosa bacteria (10%, 15%, 20%, and 25%). The analysis parameters used were pH H2O, Total N, organic C, C:N, Pb and Hg in the resulting compost. The results showed that the KK3 treatment produced higher pH H2O and Total N than other treatments. The availability of Pb metal on KK3 produced a relatively smaller value compared to other treatments, likewise, although it was not significantly different from C. The correlation results showed no significant relationship (p>0.05) between increasing doses of Pseudomonas aeruginosa and the availability of nutrients and heavy metals. The mineralization and incubation processes were factors in the study of improving the quality of compost by using Pseudomonas aeruginosa.
Computational Insights into the Antifungal Mechanisms of Coumarin and Hexanol from Ageratum conyzoides and Cyperus rotundus Against Colletotrichum spp Febryani, Noor; Benatar, Gilang Vaza; Hartini, Elya; Yulianto, Yanto; Hodiyah, Ida; Ridwan, Nur Fathurahman
Jurnal Biologi Tropis Vol. 26 No. 2 (2026): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i2.12269

Abstract

Chili anthracnose, caused by Colletotrichum spp., remains a major threat to crop productivity and fruit quality worldwide. The increasing resistance of fungal pathogens to synthetic fungicides highlights the need for sustainable, plant-based alternatives. This study provides computational insights into the antifungal mechanisms of coumarin and hexanol, two major bioactive compounds derived from Ageratum conyzoides and Cyperus rotundus. Molecular docking and molecular dynamics simulations were employed to examine the interactions of these compounds with key Colletotrichum proteins, including calmodulin, PETFP cutinase complex, and chitin deacetylase. The docking results revealed that coumarin exhibited stronger binding affinities and more stable conformations within the enzyme active sites than hexanol, forming multiple hydrogen bonds and π–π stacking interactions with catalytic residues. Molecular dynamics analyses further confirmed the structural stability and compactness of coumarin–protein complexes, indicating its potential to disrupt fungal enzymatic functions critical for pathogenicity. These findings suggest that coumarin, in particular, may serve as a promising lead compound for the development of eco-friendly antifungal agents. The study contributes to a molecular-level understanding of plant-derived antifungal mechanisms, supporting future research into the rational design and optimization of biofungicides for sustainable agriculture.
Co-Authors Alfath, Jusan Zaki Benatar, Gilang Vaza Elya Hartini, Elya Fitria, Anita Dwy IDA HODIYAH Oktavia, Revina Ridwan, Nur Fathurahman Sundawa, Rendi Yulianto, Yanto Yuliyani, Leny