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All Journal Jurnal Kedokteran Hewan
Kurniawan, Rizal Eko
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

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THE GASTROPROTECTIVE EFFECT OF Bidens pilosa L. ETHANOL EXTRACT ON ALCOHOL-INDUCED GASTRIC ULCERS IN RATS: A HISTOPATHOLOGICAL STUDY Situmorang, Elisa Rauli; Silitonga, Melva; Kurniawan, Rizal Eko
Jurnal Kedokteran Hewan Vol 19, No 3 (2025): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v19i3.47890

Abstract

The primary objective of this research was to assess the gastroprotective properties of Bidens pilosa L. leaf ethanol extract by analyzing gastric histopathology in an alcohol-induced ulcer model in albino rats (Rattus norvegicus). The research was conducted experimentally using a completely randomized design involving five groups. The rats in K- group received 0.5% carboxymethyl cellulose (CMC), while the rats in the K+ group were given 30% alcohol. Groups P1, P2, and P3 received 30% alcohol combined with ethanol extract of Bidens pilosa at doses of 250, 500, and 750 mg/kg BW, respectively. Alcohol was administered orally at a dosage of 10 mL/kg BW for 43 consecutive days. The observed parameters included histopathological features of the gastric tissue, specifically mucosal erosion, inflammatory cell infiltration, and necrosis. The results demonstrated that the extract significantly reduced alcohol induced gastric tissue damage, as indicated by lower erosion scores and inflammatory cell infiltration (P 0.05). Necrosis was not observed in any group, including in the K+ group. In conclusion, Bidens pilosa extract possesses potential gastroprotective properties, likely mediated by anti-inflammatory and cytoprotective mechanisms.
ULTRASONOGRAPHY OF THE EXTERNAL REPRODUCTIVE ORGANS IN TOM Ulum, Mokhamad Fakhrul; Maharani, Anizza Dyah Kartika; Kurniawan, Rizal Eko; Sariningrum, Arlita; Frastantie, Dilla; Erwin, Erwin; Tumbelaka, Ligaya ITA; Noviana, Deni
Jurnal Kedokteran Hewan Vol 11, No 3 (2017): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v11i3.5700

Abstract

This study aims to delineate the tissue structure of male cat external reproductive organs using ultrasound with different types of consoles and transducers frequencies through indirect method. External organ of 5 tom weighing 2-3 kg was evaluated using ultrasound with stationary console (linear transducer, 10 MHz) and portable console (linear transducer, 6.5 MHz), transcutaneously. The results showed that both console and transducer could not visualize the structure of organs sized less than 10 mm through direct method. However, the indirect method using stationary console with a 10 MHz transducer enable to visualize the organ and depicts clearly the internal organ structure such as penis and its parts, scrotum and its constituent layers, caput and cauda of epididymis, and testicles. Furthermore, portable console with 6.5 MHz transducer was still able to provide an adequate image of those organs. In general, fibrous tissues such as tunica vaginalis, tunica Dartos, funiculusspermaticus, and urethra were visible in ultrasonogram as hyperechoic structures, while soft tissues such as the parts of testicles and penis were visible as hypoechoic structures. Tissue containing fluid such as urethral lumen was visible as anechoic structure. In conclusion, indirect ultrasound imaging method was sufficient to visualize the organs sized less than 10 mm using 3-15 MHz transducer in which was currently widely used in animal health care clinics.
Co-Authors Deni Noviana Erwin Erwin frastantie, Dilla Maharani, Anizza Dyah Kartika Melva Silitonga Mokhamad Fakhrul Ulum, Mokhamad Sariningrum, Arlita Situmorang, Elisa Rauli