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All Journal Jurnal Ilmu Kesehatan Jurnal Kedokteran Mulawarman Jurnal Sains dan Kesehatan Proceeding Mulawarman International Conference on Tropical Public Health
Siagian, Loly Rotua Dharmanita
Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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GAMBARAN PROFIL LIPID DAN RASIO LIPID PADA PASIEN STROKE ISKEMIK BERULANG DI RSUD ABDUL WAHAB SJAHRANIE SAMARINDA Muhammad Fadlan Adam; Yetty Octavia Hutahaean; Loly Rotua Dharmanita Siagian
Jurnal Kedokteran Mulawarman Vol 7, No 2 (2020): Jurnal Kedokteran Mulawarman
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/j.ked.mulawarman.v7i2.4293

Abstract

Stroke iskemik merupakan tipe stroke yang paling sering terjadi pada serangan berulang. Subtipe yang paling sering terjadi adalah aterosklerosis arteri besar yang menyebabkan oklusi arteri pada otak. Abnormalitas lipid plasma merupakan penyebab utama terjadinya aterosklerosis. Rasio lipid dapat menginformasikan risiko aterosklerosis yang sulit diukur dengan pemeriksaan rutin dan peningkatan rasio lipid menggambarkan ketidakseimbangan antara fraksi lipid aterogenik dan antiaterogenik. Penelitian ini bertujuan untuk mengetahui gambaran profil lipid dan rasio lipid pada pasien stroke iskemik berulang di RSUD Abdul Wahab Sjahranie Samarinda. Penelitian ini bersifat deskriptif dengan desain studi cross sectional. Pengambilan sampel secara purposive sampling pada pasien stroke iskemik yang mempunyai riwayat stroke iskemik sebelumnya sebanyak 71 sampel. Pengambilan data profil lipid menggunakan data sekunder dari rekam medik dan rasio lipid didasarkan pada perbandingan kolesterol total (K-Total)/kolesterol high density lipoprotein (K-HDL), kolesterol low density lipoprotein (K-LDL)/K-HDL, dan trigliserida (TG)/K-HDL. Pada penelitian ini didapatkan hasil pasien stroke iskemik berulang paling banyak dengan K-Total yang optimal sebesar 49,3%, K-LDL mendekati optimal 42,2%, K-HDL rendah 71,8%, TG optimal 62,0%, rasio K-Total/K-HDL di atas nilai risiko 76,1%, rasio K-LDL/K-HDL di atas nilai risiko 63,4%, dan rasio TG/K-HDL di atas nilai risiko 52,1%. Berdasarkan hasil ini dapat disimpulkan bahwa profil lipid pasien stroke iskemik berulang di RSUD Abdul Wahab Sjahranie Samarinda paling banyak ditemukan dengan kadar K-Total dan TG yang optimal, K-LDL yang mendekati optimal, dan kadar K-HDL yang rendah. Rasio lipid yang terdiri dari rasio K-Total/K-HDL, rasio K-LDL/K-HDL dan rasio TG/K-HDL masing-masing ditemukan paling banyak dengan rasio di atas nilai risiko.
The RELATIONSHIP BETWEEN TYPES OF PLASMODIUM FALCIPARUM AND PLASMODIUM VIVAX WITH THE DEGREE OF THROMBOCYTOPENIA IN MALARIA PATIENTS AT RSUD RATU AJI PUTRI BOTUNG PENAJAM PASER UTARA Doni Suryadi; Vera Madonna Lumban Toruan; Fransiska Anggreni Sihotang; Loly Rotua Dharmanita Siagian
Jurnal Ilmu Kesehatan Vol 9 No 1 (2021): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v9i1.2218

Abstract

Malaria is a tropical infectious disease with high morbidity and mortality rates. In malaria, various kinds of haematological complications can arise, one of which is thrombocytopenia. Thrombocytopenia is most commonly encountered during acute malaria infection with varying degrees observed in both Plasmodium falciparum and Plasmodium vivax infections. The purpose of this study was to determine the relationship between the types of Plasmodium falciparum and Plasmodium vivax with the degree of thrombocytopenia in malaria patients at the Ratu Aji Putri Botung Penajam Paser Utara Hospital. This research is an observasional analytic study with cross sectional method. The data was taken by using purposive sampling method from the medical records of malaria patients hospitalized in Ratu Aji Putri Botung Penajam Paser Utara Hospital in the period of January 2013 - August 2018. Data analysis used the Chi-square test. Of the 310 malaria patients who were study subjects, 60,3% (n = 187) were infected with Plasmodium falciparum and 39,7% (n = 123) were infected with Plasmodium vivax. Most of the research subjects were male (95,8%) who were dominated by adults (56,5%). As many as 90% of malaria patients experienced thrombocytopenia with mild, moderate, and severe thrombocytopenia respectively 29,4% ; 56,6% ; 14,0%. Severe thrombocytopenia was more common in falciparum malaria patients (16,4%). The statistical test result for the type of Plasmodium with the degree of thrombocytopenia were p = 0,139. It was concluded that there was no relationship between the types of Plasmodium falciparum and Plasmodium vivax with the degree of thrombocytopenia in malaria patients.
Hubungan Jenis Plasmodium falciparum dan Plasmodium vivax dengan Kejadian Anemia pada Pasien Malaria di RSUD Ratu Aji Putri Botung Penajam Paser Utara: Relationship between Plasmodium falciparum and Plasmodium vivax Types with the Incidence of Anemia in Malaria Patients at Ratu Aji Putri Botung Hospital, Penajam Paser Utara Doni Suryadi; Vera Madonna Lumban Toruan; Fransiska Anggreni Sihotang; Loly Rotua Dharmanita Siagian
Jurnal Sains dan Kesehatan Vol. 3 No. 2 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i2.283

Abstract

Malaria is a disease caused by Plasmodium infection that is still a health problem in the tropical area including Indonesia. Penajam Paser Utara is the only district with a high level of malaria endemicity outside eastern of Indonesia which is located at the Province of East Kalimantan. Malaria can cause various complications including haematological abnormalities. Haematological abnormalities that are often found in both falciparum malaria and vivax malaria is anaemia. The purpose of this study was to determine the relationship between the types of Plasmodium falciparum and Plasmodium vivax with the incidence of anaemia in malaria patients at Ratu Aji Putri Botung, Penajam Paser Utara hospital. This research is an observational analytic study with cross sectional method. The data was obtained from medical records of hospitalized malaria patients at Ratu Aji Putri Botung Penajam Paser Utara hospital in the period of January 2013 – August 2018 by purposive sampling method. The data were analyzed using the Chi-square test. The subjects of the study were 310 malaria patients consisting of 60,3% (n=187) patients infected with Plasmodium falciparum and 39,7% (n=123) patients infected with Plasmodium vivax. The majority of research subjects were male (95,8%) and were in the 26 – 40 years age group (56,5%). Anaemia was found in 49% of malaria patients dominated by vivax malaria patients (52%). Statistical test result between types of Plasmodium with the incidence of anaemia was p = 0,391. It was concluded that there was no association between the types of Plasmodium falciparum and Plasmodium vivax with the incidence of anaemia in malaria patients.
Design and Evaluation of an Elective Malaria Surveillance Module for Medical Education in East Kalimantan Anggraini, Fitria Dewi Puspita; Zubaidah, Mona; Rahma, Khairunnida; Toruan, Vera Madonna Lumban; Retnaningrum, Yuliana Rahmah; Siagian, Loly Rotua Dharmanita; Pratiningrum, Moriko
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Malaria remains a significant public health burden in Indonesia, with over 230 million people in transmission risk areas. Strengthening surveillance systems is crucial for elimination, requiring competent health professionals. Objective : This study developed and validated a malaria surveillance elective module for East Kalimantan, Indonesia. Research Methods/ Implementation Methods : This research employed a Research and Development design with a descriptive quantitative approach at the Faculty of Medicine, Mulawarman University, from September 2024 to September 2025. The development process included needs analysis surveys distributed to medical students and lecturers, expert validation of content validity and media quality, and pilot implementation with pre-post knowledge assessments. The sample comprised 113 medical students from the 2024 cohort. Expert validation involved content specialists and media design experts who assessed the module using standardized rubrics. Data were analyzed using descriptive statistics to determine feasibility scores, validity levels, and learning effectiveness Results : Needs analysis revealed high demand for contextualized malaria surveillance materials among students and lecturers. Expert validation yielded content feasibility and linguistic appropriateness scores of 60–80%, categorized as good to very good, while media validation confirmed design quality met educational standards. Pilot implementation with 106 students showed significant knowledge improvement, with scores increasing 46.96% from pretest average of 66 to post-test average of 97. Student attendance reached 84.8%, indicating strong engagement. Conclusion/Lesson Learned : The malaria surveillance module demonstrated strong validity and effectiveness in enhancing medical student competencies. It is contextually appropriate for endemic regions and recommended for integration into medical curricula to strengthen disease surveillance capabilities among future health professionals in Indonesia
Co-Authors Anggraini, Fitria Dewi Puspita Doni Suryadi Doni Suryadi Fransiska Anggreni Sihotang Ibrahim, Arie Kalalo, Lily Pertiwi Mona Zubaidah Muhammad Fadlan Adam Novia Fransiska Ngo Pratiningrum, Moriko Rahma, Khairunnida Retnaningrum, Yuliana Rahmah Rivaldi, Achmad Toruan, Vera Madonna Lumban Vera Madonna Lumban Toruan Yetty Octavia Hutahaean