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All Journal Jurnal Ilmiah Manuntung Jurnal Kesehatan Global
Kalalo, Lily Pertiwi
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Agriculture, Biological Sciences & Forestry Health Professions Public Health

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SKRINING THALASEMIA-BETA MINOR PADA MAHASISWA FAKULTAS KEDOKTERAN Sihotang, Fransiska Anggreni; Siagian, Loly Rotua Dharmanita; Ngo, Novia Fransiska; Kalalo, Lily Pertiwi
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (713.562 KB)

Abstract

Thalassemia is a group of congenital hemoglobinopathy characterized by deficiency or absence of one (or more) of the globin chains that constitute hemoglobin. Thalassemia major is inherited through autosomal recessive pattern by marriage between carriers of the thalassemia gene known as thalassemia minor. Beta-thalassemia is the most common type of thalassemia. It is estimated that 10% of Indonesia's population carries the beta-thalassemia gene. However, there has been no routine screening for thalassemia gene carriers. Several recognized methods of thalassemia screening are available. One of them is screening of prospective brides using several hematology parameters such as Mentzer index and red blood cells fragility; both are relatively straightforward and inexpensive compared to hemoglobin analysis or genetic testing. This study aimed to determine the frequency of beta-thalassemia minor suspects among students in the Medical Faculty of Mulawarman University. This study was a descriptive quantitative study with cross sectional approach that involved 160 participants. Participant's blood sample was collected for complete blood count and one tube osmotic fragility test (OTOFT). Mentzer index is calculated by dividing MCV values ??with erythrocyte count. Participants were determined as beta-thalassemia minor suspects if they met following criterias: (1) MCV < 80 fL; (2) Mentzer index < 13; and (3) positive OTOFT result. This study demonstrated that 1.25% (n=2) of 160 participants were beta-thalassemia minor suspect. Further examination of hemoglobin electrophoresis or genetic testing is needed to further confirm this finding.
Analisis Pemeriksaan Tuberkulosis Tes Cepat Molekuler (TCM) Pada Kontak Erat Penderita yang Diskrining Oleh Puskesmas Danzu, Liza Danzu; Kalalo, Lily Pertiwi; Farpina, Eka; Wahyutri, Endah
Jurnal Kesehatan Global Vol 7, No 3 (2024): Edisi September
Publisher : LPPM Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jkg.v7i3.6325

Abstract

Tuberkulosis adalah suatu penyakit menular di dunia termasuk Indonesia bersama kasusnya yang meningkat menjadi 397.377 tahun 2021. Samarinda merupakan kota dengan penderita TB terbanyak di Kalimantan Timur. Puskesmas Karang Asam dan Puskesmas Baqa memiliki data pemeriksaan TCM kontak erat penderita terbanyak. Pemeriksaan TCM terhadap kontak erat diperlukan untuk mencegah penularan tuberkulosis di Samarinda. Tujuannya untuk menganalisis pemeriksaan tuberkulosis TCM pada kontak erat penderita di wilayah kerja Puskesmas Karang Asam dan Puskesmas Baqa. Jenis penelitian ini adalah deskriptif menggunakan desain penelitian retrospektif. Sampel penelitian adalah kontak erat penderita yang melakukan pemeriksaan TCM sebanyak 45 sampel dengan teknik total sampling. Berdasarkan usia sebanyak (86,7%) sampel berusia 15-50 tahun termasuk 2 sampel positif. Jenis kelamin laki-laki (48,9%) 1 sampel positif dan Perempuan (51,1%) 1 sampel positif. Lama kontak 6 bulan (95,6%) semua negatif dan kontak ≥6 bulan (4,4%) 2 sampel positif. Kepadatan hunian cukup (75,6%) didapatkan 1 sampel positif sedangkan kepadatan hunian kurang didapatkan 1 sampel positif. Status gizi sampel normal (60%) dengan 1 sampel positif dan status gizi gemuk (20%) didapatkan 1 sampel positif. Pendidikan (71,1%) pada tingkat SMA-keatas dengan 1 sampel positif dan (28,9%) pada tingkat SMA-kebawah dengan 1 sampel positif. Status pekerjaan sampel yang bekerja (68,9%) 1 sampel positif dan yang tidak bekerja (31,1%) didapatkan 1 sampel positif. Serta resisten rifampisin (0%) sampel negatif. Diperoleh kesimpulan Hasil pemeriksaan Tuberkulosis TCM pada Kontak Erat Penderita terlihat signifikan pada karakteristik usia dan lama kontak.Kata kunci: Kontak Erat, TCM, TB
Co-Authors Danzu, Liza Danzu Endah Wahyutri Farpina, Eka Fransiska Anggreni Sihotang Novia Fransiska Ngo Siagian, Loly Rotua Dharmanita