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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. CRJIM (Clinical and Research Journal in Internal Medicine)
Setyowati, Lita
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Tuberous Sclerosis Complex : A Case Report Rofiq, Aunur; Setyowati, Lita; Nugrahani, Aninda Fitri
Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol 15, No 2 (2019): December 2019
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.228 KB) | DOI: 10.22219/sm.Vol15.SMUMM2.9935

Abstract

Tuberous Sclerosis Complex (TSC) is an autosomal dominant inherited neurocutaneous disorder. Tuberous Sclerosis Complex is caused by mutations in tumor suppressor gene (TSC), both TSC1 and TSC2.  In approximately two-thirds of cases neither parent has signs of TSC and the disease is caused by a de  novo mutation. Tuberous Sclerosis Complex is classically identified by the Vort's triad in the presence of angiofibroma, mental retardation, and epilepsy. A 17-year-old woman with a major complaint of a facial bump that appeared at birth and got bigger when she reached puberty. There are white patches on the patient's body from birth. On the scalp obtained the presence of skin color plaque, while at the back and right knee obtained shagreen patch. Patientwas diagnosed with epilepsy and mental retardation by the pediatric department. No family history has the same complaints as patient. Histopathologic examination of facial bumps taken by shaving biopsy suggests the presence of hemangiomas. Based on the clinical diagnostic criteria from International Tuberous Sclerosis Complex Consensus Conference 2012, the patient meets two major criteria, macular hypopigmentation and shagreen patch so it is included in "definite diagnosis".
Increasing Adolescents' Knowledge in Indonesia of HIV and STD in Leading-Up Three Zero HIV/AIDS 2030 Indiastari, Dewi; Setyowati, Lita; Sutanto, Heri; Budiarti, Niniek; Rosandi, Millanitalia; Dwitarahma, Marshandyar
Clinical and Research Journal in Internal Medicine Vol. 5 No. 1 (2024): Volume 5 No 1, May 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.01.06

Abstract

During the transition period of puberty, adolescents experience physical, psychological, and ways of thinking, which social and environmental changes will have a significant impact on adolescents. Improper self-control becomes a threat that can damage the morale and future of adolescents, including choosing the wrong environment resulting in drug abuse, unwanted pregnancies, abortions, sexually transmitted infections, HIV, and AIDS. This community service activity aims to increase the knowledge and importance of youth awareness in Malang about HIV and STIs. This activity is an online lecture-based activity (webinar) and live event assisting teenagers in Malang area. It is held for seven weeks by providing education about what HIV is, why it must be avoided—the dangers of sexually transmitted infections online followed by a discussion session. The activity was attended by 763 participants aged 10-20 years and 114 guardians of students and laypeople. The results obtained during the activity showed an increase in the post-test scores compared to the values before getting the webinar. A long-term evaluation still needs to be carried out to assess the absorption rate of the material that has been carried out on the quality of life of webinar participants. The conclusion obtained from this activity is that the knowledge of webinar participants, especially teenagers, about HIV/AIDS has increased, and knowledge is a fundamental thing that must be instilled in adolescents as early as possible to prevent HIV transmission in adolescents.
Co-Authors AUNUR ROFIQ Dwitarahma, Marshandyar Heri Sutanto Indiastari, Dewi Niniek Budiarti B Nugrahani, Aninda Fitri Rosandi, Millanitalia