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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Biosaintifika: Journal of Biology & Biology Education
Syafah, Lailiiyatus
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Medicinal plants documentation of Dayak Banuaq tribe in Intu Village, Nyuatan District, West Kutai, East Kalimantan Lestari, Indah; Syafah, Lailiiyatus
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 4, No 1 (2019): April
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1079.829 KB) | DOI: 10.22219/farmasains.v4i1.7896

Abstract

The Dayak Benuaq tribe is one of the tribes in Indonesia who live in East Kalimantan. They have various knowledge related to raw materials and medical treatment traditions for generations that have never been documented, especially in Intu Lingau Village, Nyuatan District, West Kutai, East Kalimantan. This study aims to documentation of medicinal plants and herbs of the local communities. The finding shows that there are 104 plants used, which is divided into 34 families. The most common plant parts used in the treatment were leaves, the most common processing method was boiling, and the most utilized method was by drinking.
Fermented Black Rice Extract (Oryza sativa) Induces Morphological Changes in Pathogenic Microorganisms Wijayanti, Ernanin Dyah; Syafah, Lailiiyatus; Rahayu, Lina Oktavia; Wulandari, Dita; Ibrahim, Zalikha
Biosaintifika: Journal of Biology & Biology Education Vol. 17 No. 1 (2025): April 2025
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v17i1.17185

Abstract

Black rice (Oryza sativa L.) contains nutrients and bioactive compounds with potential application in health, including antimicrobial properties. To date, the application of fermentation to black rice to enhance its bioactivity, particularly as an antimicrobial, remains unclear. This study aims to evaluate the antimicrobial activity of solid fermented black rice against Gram-positive bacteria, Gram-negative bacteria, and fungi. Black rice was fermented using Saccharomyces cerevisiae under solid-state conditions. Extraction was carried out by maceration using 96% ethanol. Antimicrobial activity was assessed using the well diffusion test method, agar dilution, and scanning electron microscope (SEM). Fermented black rice extract showed antimicrobial activity against all tested microbes. The minimum inhibitory value obtained was 20% against all microbes, but the minimum bactericidal/fungicidal concentration (MBC/MFC) could not be determined. The SEM analysis showed morphological changes in microbes exposed to fermented black rice extract, including cell shrinkage, elongation, and lysis in Bacillus cereus, fragmentation and irregular cell shape in Escherichia coli, cell size reduction in Staphylococcus aureus, and bleb formation in Candida albicans. These changes indicate the mechanism of microbial growth inhibition. We found that fermented black rice (EFBR) extracts produce different effects from unfermented black rice extracts (EUBR), which tend to induce biofilm formation. We propose that EFBR functions as an antimicrobial by rupturing cell walls, preventing cell division and DNA synthesis. This research provides new insights into natural antimicrobial mechanisms at the cellular level and offers a potential alternative for addressing antimicrobial resistance. Solid fermented black rice may serve as a valuable source of antimicrobial compounds for developing health products or natural preservatives.
Co-Authors Ernanin Dyah Wijayanti Ibrahim, Zalikha Rahayu, Lina Oktavia Wulandari, Dita