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All Journal Medical Journal of Indonesia The New Ropanasuri Journal of Surgery Jurnal Ilmu Bedah Indonesia Jurnal Locus Penelitian dan Pengabdian
Darwis, Patrianef
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Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology

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Journal : Jurnal Locus Penelitian dan Pengabdian

 1 
Comparison of Intima-Media-Thichness, Brachialic Artery VF and VF Draining Vein CKD with Diabetes and Non-Diabetes Performed AVF-Brachiosephiccia at RSCM Herwen, Herwen; Patrianef, Patrianef; Vidiawati, Dhanasari
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 8 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i8.4750

Abstract

Brachiocephalic arteriovenous fistula (AVF) is the recommended vascular access for long-term hemodialysis. However, AVF failure rates remain high, particularly among patients with diabetes mellitus (DM). Diabetes contributes to vascular structural changes, such as increased intima-media thickness (IMT) and reduced volume flow (VF), which may affect AVF maturation success. To compare changes in IMT, brachial artery volume flow, and draining vein volume flow in chronic kidney disease (CKD) patients with and without DM who underwent brachiocephalic AVF creation. This was a retrospective cohort study conducted at Cipto Mangunkusumo National General Hospital between April and June 2025. A total of 42 CKD patients were enrolled and divided into two groups: 21 with DM and 21 without DM. IMT and volume flow were measured using Doppler ultrasound at weeks 0, 2, and 6 after AVF creation. Data were analyzed using the Mann-Whitney test and independent T-test, depending on data distribution. Forty two participants met the inclusion criteria. No significant differences were found between the DM and non-DM groups regarding changes in brachial artery IMT (p = 0.918), brachial artery volume flow (p = 0.538), or draining vein volume flow (p = 0.642) at week 6. Although both groups showed a trend of increased VF from week 0 to week 6, the differences were not statistically significant. There were no significant differences in changes in IMT, brachial artery volume flow, or draining vein volume flow between CKD patients with and without DM following brachiocephalic AVF creation.
Relationship of Saphenous Magna Vein Diameter to Venous Occlusion & Revised Venous Clinical Severity Score (rVCSS) in Patients with Chronic Venous Insufficiency (IVK) Post-Endovenous Microwave Ablation (EMA) Rachmanto, Ary; Patrianef, Patrianef; Kekalih, Aria
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 8 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i8.4751

Abstract

Chronic venous insufficiency (IVK) is characterized by impaired reverse blood flow in the lower extremities. Endovenous microwave ablation (EMA) is a minimally invasive procedure with advantages on large diameter veins. This study aimed to determine the relationship between the diameter of the great saphenous vein (GSV) and venous occlusion in the first week and the change in the Revised Venous Clinical Severity Score (rVCSS) in the first month post-EMA. This retrospective cohort design study involved 47 patients from RSCM, Hermina Bekasi Hospital and Hermina Depok Hospital for the January-December 2024 period. Data collection used medical record tracing, GSV diamter, GSV venous occlusion, rVCSS score. Bivariate analysis with Chi-Square or Fischer Test, multivariate analysis with multiple logistic regression while diagnostic parameter analysis with ROC curve. The venous occlusion rate reached 87.2%, and the change in rVCSS score was 63.8%. There was a significant relationship between GSV diameter and GSV occlusion [p<0.001; MD -2.101 (95% CI: -2.84; -1.36)] and with changes in rVCSS score [B=1.188; p=0.029; OR 3.28 (95% CI: 1.13–9.53)]. The GSV diameter threshold value of 6.55 mm was a good predictor of occlusion (75.6% sensitivity, 100% specificity), but not good for rVCSS change (70% sensitivity, 52.9% specificity). Other factors such as gender, age ?60 years, hypertension, diabetes, and obesity were not significantly related. GSV diameter was significantly associated with venous occlusion and changes in rVCSS scores post-EMA. A cut-off value of 6.55 mm can be a good predictor of occlusion.
Co-Authors Aria Kekalih Bakri, Ahmad Bangsawan, Kiwah Andanni Basri, Novrizal S. Dedy Pratama Dhanasari Vidiawati Fachriza, Ihza Fakhri Rahman, Fakhri GAMPO ALAM IRDAM, GAMPO ALAM Grace Wangge, Grace Herwen, Herwen I Gusti Agung Bagus Krisna Wibawa Megatia, Ika Muradi, Akhmadu Ocsyavina, Ocsyavina Pamungkas, Wisnu Pratama, Deddy Rachmanto, Ary Raharja, Putu Angga Risky Sari Febriana, Sari Simanjuntak, Bakti H Sitorus, Londung B. Subrata, Feyona H Telaumbanua, Rizky Vanto, Yoni Yang, Andrew Jackson