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Studi Literatur Perbedaan Ekspresi Messenger Ribonucleid Acid (mRNA) Reseptor Androgen Setelah Pemberian Testosteron antara Penis dan Kelenjar Prostat Tikus Wistar Jantan (Rattus Norvegicus) Pascakastrasi Arini, Luh Ari
JURNAL KESEHATAN REPRODUKSI Vol 6, No 1 (2019)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.56 KB) | DOI: 10.22146/jkr.37823

Abstract

Background: Aging process (andropause) in men will cause a decrease in testosterone hormones, in other that decrese of androgen receptor (testosteron and dhyhidrtestosterone) in target organ, can be seen from AR mRNA expression. Andropause finaly impact of male reproductive organ, so given testosterone hormone therapy is important to restore the condition. Giving testosterone hormone causes increase the expression of AR mRNA in the prostate gland and penis, but in these two organs there is a different increase.Objective: to know the difference of expression AR mRNA after administration of testosterone between prostate gland and penis.Method: This article used literature review from database of intisari sains medis.Results and Discussion: AR mRNA expression in the prostate gland is smaller than the penile tissue, due to the prostate gland in addition to the 5α reductase enzyme there are also many aromatase enzymes. In the normal prostate gland the amount of 5α reductase is small, so the addition of testosterone is converted to DHT but also in aromatization to estrogen. Therefore, fewer androgen receptors are found compared to the tissue of the penis, in addition expression of AR mRNA in the preputial penis is higher than the prostate gland.Conclusion: Penile tissue is more responsive to testosterone and improves the function and maintenance of tissue especially in old. Keywords: androgen receptor mRNA; testosterone; penis and prostate
Women’s Reproductive Health In A Tourism Setting: A Descriptive Study In Lovina, Bali Armayanti, Luh Yenny; Sulyastini, Ni Komang; Dyantari, Putu Eva Yuni; Arini, Luh Ari; Karma, Putu Rama Pratama; Irmayanti, Putu Cynthia Devi
Jurnal Riset Kesehatan Nasional Vol. 10 No. 1 (2026)
Publisher : Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37294/jrkn.v10i1.851

Abstract

Women’s reproductive health is shaped by social, economic, cultural, and environmental factors, particularly in high-mobility settings such as tourism areas. In Lovina, Bali, tourism activities may influence reproductive health through lifestyle changes, psychosocial stress, and sexual behavior. This study aimed to describe the reproductive health profile of women living in this tourism area. A quantitative descriptive study with a cross-sectional design was conducted among 160 women aged 20–45 years, selected through purposive sampling. Data were collected using structured questionnaires and analyzed descriptively. Most respondents were aged 30–39 years, predominantly married, and had lived in the area for over five years. The majority experienced menarche at 13–14 years and reported normal menstrual cycles (21–35 days). Most had a history of pregnancy, commonly one to two pregnancies, although some had no live births. Contraceptive use was relatively high, especially injectable methods, but more than one-third had never used contraception. Miscarriage and unplanned pregnancy were reported by a notable proportion, while pregnancy complications were less common. Sexual behavior was generally low risk, though a small proportion reported sexually transmitted infections. Reproductive health was favorable, but gaps in contraception and STI prevention remain.  Keywords: Reproductive Health, Women, Tourism Area