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Perbandingan Aktivitas Antioksidan Pada Ekstrak Serta Krim Kobinasi Ekstrak Jeruk Nipis (Citrus Aurantifolia) Dan Daun The Hijau (Camellia Sinensis) Untuk Treatment Striae Gravidarum Rahman, Alief Putriana
Acta Pharmaceutica Indonesia Vol. 49 No. 2 (2024)
Publisher : School of Pharmacy Institut Teknologi Bandung

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Abstract

Striae Gravidarum (SG) are stretch marks seen in pregnant and postpartum women. Treatments for SG aim to reduce redness and enhance pigmentation and collagen. Chemical peeling treatment can be harmful. They may cause liver, kidney, and skin issues, including inflammation and skin loss. Meanwhile, laser treatments may lead to skin inflammation for 2-4 days post-procedure. Despite this, they remain popular. Topical retinoic acid can cause birth defects and miscarriages if used in pregnancy. This highlights the need for natural treatments for SG. This study aimed to find the content and the antioxidant activity of lime peel extract, green tea, and cream combination both of extract. Besides, another goal was to determine physical characteristics formulation in the cream preparation. Method of this research is phytochemical screening for extract. Measure Vitamin C, EGCG and antioxidant activity using UV-Vis spectrophotometry. The cream contains 10% lime and 6% green tea extracts. This study found lime peel and green tea extracts each yielded less than 10%. Phytochemical tests revealed lime extract has alkaloid, Steroid, Saponin, Flavonoids, Tannins, and Antraquinone. Lime peel extract has vitamin C 16,56103 mg/100 mg of extract. Green tea extract contains EGCG 22,5114 mg/100 mg of extract. Lime peel extract's antioxidant activity is 268,3130 ppm. For green tea, it's 154,4009 ppm . The combination cream has 115,7629 ppm of antioxidant activity. Its physical properties meet good cream standards. The conclution of this research is combination cream of lime peel and green tea extract has the highest antioxidant activity
FORMULASI GEL ANTIINFLAMASI SEDIAAN EKSTRAK DAUN KUBIS (BRASSICA OLERACEA VAR. CAPITATA) UNTUK MENGURANGI PEMBENGKAKAN PAYUDARA PASCAPERSALINAN A'yun, Qurratul; Rahman, Alief Putriana; Alrosyidi, Ach. Faruk
Nusantara Hasana Journal Vol. 4 No. 10 (2025): Nusantara Hasana Journal, March 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i10.1361

Abstract

Cabbage leaves (Brassica oleracea var. capitata) are known to have potential anti-inflammatory activity so they can be used as therapy to reduce swelling, especially in postpartum mothers. Its main active ingredients are flavonoids and phenolics, which play a role in inhibiting the inflammatory process This study aims to develop a gel based on cabbage leaf extract as a safe and effective topical preparation to treat postpartum swelling. The research was conducted using an experimental method using female mice as a test animal model. Cabbage leaf extract was obtained through the maceration method with a 96% ethanol solvent, which was then formulated into a gel with three variations in extract concentration (2.5%, 5%, and 7.5%). Evaluation included preparation quality tests (organoleptics, homogeneity, pH, viscosity, and dispersibility) as well as anti-inflammatory tests using carrageenan edema models. Results showed that all gel formulas met the quality criteria of the preparation with an appropriate pH for optimal skin application and spread. Anti-inflammatory tests showed that the formula with a 5% extract concentration had the best activity, with a significant decrease in the volume of edema in mice compared to positive and negative controls. In addition, the viscosity and dispersibility of the gel are in accordance with the standards of topical preparations. In conclusion, cabbage leaf extract gel has the potential to be a safe and effective anti-inflammatory pharmaceutical preparation for clinical applications, particularly in reducing postpartum swelling. This research contributes to the development of natural ingredients-based drugs with wide use prospects in the field of maternal health.
Education on Medication Use During Ramadhan at Kowel Community Health Center, Pamekasan Alrosyidi, Ach. Faruk; Dewi, Ika Oktaviana; Wahyudi, Imam; Fadiyanto, Sofyan; Hanafi, Hanafi; Mafruhah, Anisatul; Rahman, Alief Putriana; Hasanah, Naili Uswatun; Setiawan, Nanang; Muria, Risky Mezi
Jurnal Pengabdian Masyarakat Al-Fatimah Vol. 2 No. 1 (2025): Edisi III, Juni 2025
Publisher : Institut Agama Islam Al-Fatimah Bojonegoro

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Abstract

This study aims to provide optimal education about drug use during the month of Ramadan at the Kowel Community Health Center, Pamekasan. The methods used include direct outreach to the community using a face-to-face concept, distribution of educational materials, and interactive question and answer sessions. The results of the activity show an increase in public knowledge regarding the correct and safe way to use medication during fasting. In conclusion, this education is effective in increasing public awareness of the importance of understanding the use of drugs when fasting. Recommendations for similar activities in the future are to intensify outreach through various media and involve more parties, including health workers and community leaders, to achieve a wider and more sustainable impact
PELATIHAN PEMBUATAN SABUN CAIR PENCUCI ALAT MAKAN DI PONDOK PESANTREN MA MIFTAHUL ULUM BETTET KABUPATEN PAMEKASAN Rahman, Alief Putriana
Collaborative: Jurnal Pengabdian Masyarakat Vol. 1 No. 1 (2023): Desember
Publisher : CV. Jendela Gagasan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61743/collaborative.v1i1.33

Abstract

Salah satu bentuk PHBS (Prilaku Hidup Bersih dan Sehat) yang bisa dilakukan di Institusi pendidikan pondok pesantren adalah dengan mencuci alat makan dengan menggunakan sabun pencuci piring antibakterial. Sehingga selain makan yang begizi, alat makan yang digunakan juga bersih dan bebas dari bakteri. Berdasarkan data awal yang diambil peneliti menyebutkan bahwa 75% santri tidak mencuci piringnya dengan sabun pencuci piring. Sabun pencuci alat makan dapat menghilangkan kotoran dan membunuh bakteri yang berasal dari sisa makanan dan minuman.Tujuan Penelitian ini yaitu untuk meningkatkan pengetahuan siswa tentang pentingnya penggunaan sabun cuci alat makan dan cara pembuatan sabun cuci alat makan. Metode penelitian ini adalah menggunakan pengisian pretest dan posttest, penjelasan materi tentang pentingnya peggunaan sabun cuci alat makan menggunakan PPT dan pelatihan pembuatan sabun cuci alat makan secara langsung. Hasil dari penelitian ini diambil dari hasil pretest dan posttest dan dianalisi menggunakan SPSS pair T test. Hasil analis data diperoleh rata-rata nilai post test lebih besar dibandingkan dengan nilai pretest dan diperoleh nilai signifikan kurang dari 0,05 (0,000). Hasil tersebut menunjukkan bahwa adanya peningkatan pengetahuan santri MA Miftahul Ulum Bettet tentang pentingnya penggunaan sabun cuci alat makan dan cara pembuatan sabun cuci alat makan
Strengthening Friendship and Synergy: ASPETRI Malang Regency Halal Bihalal Activity as an Effort to Strengthen the Organization Wibowo, Teguh Setiawan; Rahman, Alief Putriana; Utami, Ndari Sri
Jurnal Pengabdian West Science Vol 4 No 05 (2025): Jurnal Pengabdian West Science
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/jpws.v4i05.2219

Abstract

The Halal Bihalal event held by ASPETRI Malang Regency took place on April 15, 2024, in Mendit, Malang, with approximately 40 participants. The event aimed to strengthen interpersonal bonds among members and enhance organizational synergy following the celebration of Eid al-Fitr. Beyond a moment of reunion, the event served as a platform for consolidation and aligning visions in the development of traditional herbal medicine. A gesture of care for participants' well-being was reflected through the distribution of wedang rempah, a traditional herbal drink known for boosting immunity and warming the body. This activity illustrates that the Halal Bihalal tradition not only reinforces social relationships but also functions as a cultural and health-based organizational strengthening strategy.