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All Journal Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Journal of Pharmaceutical and Sciences. Jurnal Pharmacia Mandala Waluya
Sahumena, Muhammad Handoyo
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Formulasi Sediaan Masker Gel Peel-Off Ekstrak Etanol Kulit Buah Pisang Kepok (Musa paradisiaca L.) Sebagai Antioksidan Yudistin Ramba, Wiwis; Sahumena, Muhammad Handoyo; Nasir, Nur Herlina
Jurnal Pharmacia Mandala Waluya Vol. 2 No. 1 (2023): Jurnal Pharmacia Mandala Waluya
Publisher : Prodi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54883/jpmw.v2i1.61

Abstract

Kulit adalah salah satu organ paling penting dari tubuh kita. Masker gel peel-off yang digunakan diharapkan dapat membersihkan dan mencerahkan kulit. Dari beberapa penelitian diketahui kulit pisang kepok terkandung senyawa flavonoid yang berpotensi sebagai antioksidan, dan tujuan dari penelitian ini untuk mengetahui formulasi sediaan masker gel peel-offI ekstrak etanol kulit buah pisang kepok sebagai antioksidan. Jenis penelitian ini adalah penelitian analitik untuk mengetahui aktivitas antioksidan pada ekstrak kulit buah pisang kepok dan untuk mengetahui pengaruh variasi konsentrasi polivinil alkohol (PVA) sebagai gelling agent. Konsentrasi PVA pada setiap formula adalah 8%, 10% dan 12%. Masker gel peel-off dikarakterisasi meliputi uji organoleptis, homogenitas, pH, daya sebar, viskositas, dan waktu mengering. Hasil penelitian menunjukkan pada sampel ekstrak kulit buah pisang kepok mengandung metabolit sekunder yaitu alkaloid, flavonoid, tanin, saponin, dan fenolik. Ekstrak kulit pisang kapok memiliki aktivitas antioksidan dengan nilai IC50 dengan kategori sangat kuat yaitu 13,12 ppm. Formulasi masker gel peel-off ekstrak kulit pisang kepok memiliki warna coklat, berbau khas dan konsistensi semipadat. Homogenitas pada semua sediaan tidak ada gumpalan dan tidak terdapat partikel kasar. Daya sebar pada semua sediaan memenuhi persyaratan daya sebar yang baik (5-7 cm). Uji viskositas pada semua sediaan memenuhi syarat (50-1000 Dps). Pada uji pH dan waktu mengering sediaan memenuhi syarat nilai pH pada kulit wajah (4,5-6) dan waktu mengering (15-30 menit).
Sunscreen Innovation: Development of a Water-Resistant Compact Powder Formula Based on Titanium Dioxide for Optimal UV Protection Muliadi, Rahmat; Aspadiah, Vica; Sahumena, Muhammad Handoyo; Aftira, Nidya
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.961

Abstract

Background: Ultraviolet (UV) radiation contributes to skin aging and damage, necessitating effective protection. Sunscreens offer a solution by absorbing, scattering, and reflecting UV radiation, especially those containing titanium dioxide, which has strong UV-blocking properties. Innovation in the form of compact powder sunscreen presents a practical and efficient daily protection approach due to its easy-to-apply formulation. Objective: This study aimed to evaluate the physical characteristics of compact powder sunscreen formulations, including organoleptic properties, pH, homogeneity, adhesion, hardness, and the effect of titanium dioxide on the Sun Protection Factor (SPF) value. Methods: Formulations were prepared and evaluated through physical tests, including organoleptic assessment, pH, homogeneity, adhesion, and hardness, as well as SPF measurement using a UV-Vis spectrophotometer. Results: Titanium dioxide contributed to the light brown color, smooth texture, and vanilla scent of the formulations. It also enhanced the SPF value. The most optimal formulation was Formula 4, containing 25% titanium dioxide, which met the desired physical criteria and achieved an SPF value of 15.06, categorized as ultra protection. Conclusion: The addition of titanium dioxide positively affected the physical characteristics and SPF value of compact powder sunscreen. Formula 4, with 25% titanium dioxide, demonstrated the best results and the highest SPF, making it the most optimal formulation for UV protection
Eco-friendly Powder Sunscreen Combining Kaolin and Zinc Oxide with Determination of Sun Protection Factor Aspadiah, Vica; Sahumena, Muhammad Handoyo; Suryani, Suryani; Muliadi, Rahmat; Sinta, Dwi
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 13 No. 1 (2026)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v13i1.19626

Abstract

Excessive exposure to UV radiation can cause skin damage, making sunscreen use necessary. However, chemical ingredients may have negative impacts on marine ecosystems. Therefore, an eco-friendly powder sunscreen combining kaolin and zinc oxide was developed. This study aimed to determine the formulation, evaluate the physical characteristics, and assess the effectiveness of UV protection by determining the SPF value. The study used a mixing method followed by physical characteristic testing, including organoleptic evaluation, pH measurement, homogeneity, adhesion, moisture content, fineness degree, and SPF determination using a UV-Vis spectrophotometer. The results showed that the combination of kaolin and zinc oxide produced a formula with good physical characteristics, including a light brown colour, a distinctive odour, a smooth and homogeneous texture, a pH ranging from 6.78 to 7.29, adhesion ranging from 82% to 90%, moisture content ranging from 0.05% to 0.25%, a powder fineness of 95%, and SPF values ranging from 13.69 to 16.01. The best formulation was Formula 5, containing 25% kaolin and 25% zinc oxide, which met the required characteristics and showed the highest SPF value of 16.01. This combination of ingredients can be utilised to produce an effective and environmentally friendly loose powder sunscreen.
Co-Authors Aftira, Nidya Aspadiah, Vica Nasir, Nur Herlina RAHMAT MULIADI, RAHMAT Sinta, Dwi Suryani Suryani Yudistin Ramba, Wiwis