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All Journal Jurnal Ilmu Alam dan Lingkungan Jurnal Pembelajaran dan Biologi Nukleus
Fathia, Mona
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Veterinary

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The Potential of Various Matoa Plant (Pometia pinnata) Extracts as Antibacterial Agents: Systematic Literature Review Sarima, Sarima; Pistanty, Mingle A; Fathia, Mona; Winanda, Witri
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 11, No 2: Jurnal Pembelajaran Dan Biologi Nukleus June 2025
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v11i2.7505

Abstract

Background: Bacteria in nature can have various effects on human life, including the development of diseases. Consequently, it is necessary to regulate or inhibit the growth of harmful bacteria. One method of doing so is through the use of natural ingredients, such as Matoa (Pometia pinnata). This study aims to provide a literature review on the potential of various Matoa plant extracts as antibacterials. Methodology: The investigation was conducted using the PRISMA approach, which involved the systematic literature review method. Electronic databases, including PubMed, ScienceDirect, Scopus, and Google Scholar, were searched from 2010 to 2024. "Pometia pinnata" is a search term that encompasses " Pometia pinnata as antibacterial" and "Antibacterial Activity of Pometia pinnata." A qualitative analysis was conducted on 22 articles that satisfied the inclusion criteria following the selection process. Findings: The review results indicated that the extracts of matoa's leaves, seeds, and bark contain active compounds, including flavonoids, tannins, saponins, alkaloids, and other phenolic compounds, which exhibit antibacterial activity. Despite the large potential, the majority of the research is still exploratory and has not yet progressed to the clinical trial stage. Consequently, additional, more intensive research is required to investigate the mechanism of action, toxicity, and potential clinical applications of herbal medicines derived from indigenous Indonesian plants. Contribution: This review highlights the antibacterial potential of matoa (Pometia pinnata) and underscores the need for further studies on its mechanism, toxicity, and clinical application, thereby guiding future research on Indonesian herbal medicine
Potensi Senyawa Bioaktif dari Bajakah Spatholobus littoralis Hassk. Sebagai Antikanker terhadap Sel MCF-7 secara In Vitro Habibi, Alif Rahman; Arfan, Alya Rahmaditya; Anwar, Khoirul; Azizah, Anggia; Fathia, Mona; Winanda, Witri; Berlyansyah, Azizul
Jurnal Ilmu Alam dan Lingkungan Vol. 16 No. 2 (2025): Jurnal Ilmu Alam dan Lingkungan
Publisher : Universitas Hasanuddin

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Bajakah (Spatholobus littoralis Hassk.) is a plant from the Angiospermae group, belonging to the Leguminosae family, that grows in Kalimantan. This plant contains secondary metabolites with potential anticancer activity. Cancer is characterized by uncontrolled cell proliferation beyond normal mechanisms, leading to abnormal tissue growth and invasion. It is one of the leading causes of death worldwide, including breast cancer. In 2022, approximately 2.3 million women were diagnosed with breast cancer, with 670,000 deaths recorded globally, while around 1.63 million women were still living with the disease by the end of the year. This study aimed to evaluate the anticancer activity of Bajakah Spatholobus littoralis Hassk. against MCF-7 breast cancer cells using the MTS assay. The results showed that Bajakah extract exhibited low toxicity toward the MCF-7 cell line, with an IC50 value of 1,098.77 ppm. Therefore, it can be concluded that Bajakah Spatholobus littoralis Hassk., tested with the MTS method, is not cytotoxic to breast cancer cells. Further studies are recommended to investigate its potential effects on other cancer cell types
Co-Authors Alya Rahmaditya Arfan Azizah, Anggia Berlyansyah, Azizul Habibi, Alif Rahman Khoirul Anwar Mingle A Pistanty, Mingle A Sarima, Sarima Winanda, Witri