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All Journal Jurnal Ilmu Alam dan Lingkungan JHN: Journal of Health and Nursing
Habibi, Alif Rahman
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Potensi Senyawa Bioaktif dari Bajakah Spatholobus littoralis Hassk. Sebagai Antikanker terhadap Sel MCF-7 secara In Vitro Habibi, Alif Rahman; Arfan, Alya Rahmaditya; Anwar, Khoirul; Azizah, Anggia; Fathia, Mona; Winanda, Witri; Berlyansyah, Azizul
Jurnal Ilmu Alam dan Lingkungan Vol. 16 No. 2 (2025): Jurnal Ilmu Alam dan Lingkungan
Publisher : Universitas Hasanuddin

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Abstract

Bajakah (Spatholobus littoralis Hassk.) is a plant from the Angiospermae group, belonging to the Leguminosae family, that grows in Kalimantan. This plant contains secondary metabolites with potential anticancer activity. Cancer is characterized by uncontrolled cell proliferation beyond normal mechanisms, leading to abnormal tissue growth and invasion. It is one of the leading causes of death worldwide, including breast cancer. In 2022, approximately 2.3 million women were diagnosed with breast cancer, with 670,000 deaths recorded globally, while around 1.63 million women were still living with the disease by the end of the year. This study aimed to evaluate the anticancer activity of Bajakah Spatholobus littoralis Hassk. against MCF-7 breast cancer cells using the MTS assay. The results showed that Bajakah extract exhibited low toxicity toward the MCF-7 cell line, with an IC50 value of 1,098.77 ppm. Therefore, it can be concluded that Bajakah Spatholobus littoralis Hassk., tested with the MTS method, is not cytotoxic to breast cancer cells. Further studies are recommended to investigate its potential effects on other cancer cell types
Gambaran Kadar Timbal (Pb) Pada Air Laut Di Kawasan Tanjung Uma Lubuk Baja Kota Batam Dengan Metode Spektrometri Serapan Atom habibi, alif rahman; Zarya Sukmawati; Alif Rahman Habibi
JHN: Journal of Health and Nursing Vol. 1 No. 1 (2023): JHN: Journal of Health and Nursing, Mei 2023
Publisher : ASIAN PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58738/jhn.v1i1.275

Abstract

Kawasan perairan Tanjung Uma Kota Batam merupakan tempat yang memiliki aktivitas multifungsi, sehingga perairan tersebut rentan terhadap pencemaran logam berat seperti Pb. Penelitian ini bertujuan untuk mengetahui dan menentukan kadar timbal pada air laut dikawasan tersebut. Penelitian ini dilakukan di tiga titik. Penelitian ini merupakan penelitian deskriptif dengan metode eksperimen. Sampel penelitian di analisi menggunakan Spektrometri Serapan Atom (SSA) dilaboratorium kimia PT. SUCOFINDO BATAM. Kadar logam Pb tertinggi pada titik kedua yaitu sebesar 2,105 mg/L. Hasi analisis sampel air laut pada ketiga titik tersebut teridentifikasi telah melawati ambang batas baku mutu berdasarkan ketetapan Mentri Lingkungan Hidup Tahun 2004 No. 51 Lampiran II yaitu sebesar 0.005 mg/L.
Co-Authors Alif Rahman Habibi Alya Rahmaditya Arfan Anggia Azizah Berlyansyah, Azizul Fathia, Mona Khoirul Anwar Winanda, Witri Zarya Sukmawati