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All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia eJournal Kedokteran Indonesia
Fify Henrika, Fify
Department Of Clinical Pathology, Faculty Of Medicine, Indonesia University-Dr.Cipto Mangunkusumo Hospital Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Comparison of the Profile and TSH Levels from Several Types of Blood Collection Tubes Putra, Gunawan Eka; Sukartini, Ninik; Immanuel, Suzanna; Henrika, Fify; Indrasari, Nuri Dyah
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 26, No 2 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v26i2.1475

Abstract

Thyroid-Stimulating Hormone (TSH) is an important parameter in diagnosing thyroid disease which uses serumaccording to the World Health Organization's (WHO) recommendations. The use of plasma can help improve the TurnAround Time (TAT); however, the discrepancy with serum is unknown. A cross-sectional study using 89 blood samples wasperformed to compare TSH levels using serum tubes with clot activator (Tube I), plasma tubes with heparin (Tube II), andplasma tubes with heparin-gel separator (Tube III); and to overview of TSH levels according to gender and age. The medianof TSH levels in Tubes I, II, and III were 1.380 (0.032-7.420) μIU/mL, 1.380 (0.030-7.480) μIU/mL, and 1.360 (0.030-7.460)μIU/mL, respectively. There were no statistically significant differences in TSH levels of the three tubes. The median TSHlevels differences of Tubes II and III compared to the tube I were -0.9% (-7.2-2.2) and -1.7% (-8.0-1.6), respectively.Measurement bias observed in this study was following the specified desirable bias according to Ricos. The median TSHlevels of the male and female groups were 1.500 (0.032-4.250) μIU/mL and 1.345 (0.058-7.420) μIU/mL, respectively. MedianTSH levels of 31-40 years old age group and >61 years old age group were 1.190 (0.609-3.240) μIU/mL and 1.730 (0.088-5.760) μIU/mL, respectively. Specimens from three tubes could be used to examine TSH levels. Measurement of TSH levelsshowed a higher median in the male and older group.
DIAGNOSIS LABORATORIUM MALARIA Weny Rinawati; Fify Henrika
Majalah Kedokteran Indonesia Vol 69 No 10 (2019): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volu
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jinma.v69i10.183

Abstract

Pendahuluan: Malaria adalah penyakit tropik yang disebabkan oleh parasit dan ditularkan melalui nyamuk Anopheles. Diagnosis malaria yang cepat dan akurat merupakan bagian integral dari perawatan yang tepat bagi individu yang terkena dampak dan dalam mencegah penyebaran infeksi lebih lanjut di masyarakat. Jika tidak diobati, dapat mengalami komplikasi dan mortalitas. Diagnosis klinis didasarkan pada gejala pasien dan pada temuan fisik saat pemeriksaan. Penderita malaria sering mengalami demam, kedinginan, dan penyakit seperti flu. Temuan klinis harus dikonfirmasi dengan tes laboratorium untuk malaria. Baku emas untuk konfirmasi malaria adalah pemeriksaan mikroskopik. Penentuan spesies dilakukan berdasarkan karakteristik morfologi dari empat spesies parasit malaria manusia dan eritrosit yang terinfeksi. Namun, pemeriksaan mikroskopik tidak dapat membedakan spesies parasit pejamu primata selain manusia dengan empat spesies parasit pejamu manusia. Penentuan spesies dapat menggunakan teknik molekuler seperti polymerase chain reaction (PCR) dan pengujian mikrosatelit. Tes lain untuk diagnosis adalah rapid diagnostic test (RDT), deteksi antibodi malaria menggunakan tes indirect fluorescent antibody (IFA) dan enzyme immunoassays (EIA).
ANEMIA DAN DEFISIENSI BESI PADA SISWA SLTP NEGERI I CURUG, TANGERANG Fify Henrika; T. Silangit; Riadi Wirawan
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 15, No 1 (2008)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v15i1.943

Abstract

A research was conducted to 69 female students from a junior high school (SLtP) Negeri I Curug, tangerang aged 12–14 yearsto obtain percentages of anemia and iron deficiency in female adolescents. Anemia was found on 10.2% of the students, with 4.3%of normocytic normochromic anemia and 5.8% of microcytic hypochromic anemia. Microcytic hypochromic erythrocytes was foundon 21.7% of the subjects which consist of 2.9% iron deficiency anemia, 1.4% phase 2 iron deficiency (latent) with possibility ofhemoglobinopathy, and 2.9% phase 1 iron deficiency (pre-latent) with possibility of hemoglobinopathy. Anemia without iron deficiencywith possibility of chronic diseases and/or hemoglobinopathy was 2.9%, and without anemia nor iron deficiency but with possibility ofhemoglobinopathy was 11.6%. Iron deficiency was found among 26.1% of subjects which consist of 11.6% pre-latent iron deficiency,8.7% latent iron deficiency, and 5.8% iron deficiency anemia with 2.9% and 2.9% were normocytic normochromic anemia andmicrocytic hypochromic anemia, respectively.
The Role of Neutrophil Lymphocyte Ratio , Vitamin D, and NGAL as Cardiovascular Disease Marker in Chronic Kidney Disease Sri Suryo Adiyanti; Yusra Yusra; Suzanna Immanuel; Diana Aulia; Fify Henrika; July Kumalawati
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.048 KB) | DOI: 10.23886/ejki.9.35.192-6

Abstract

Chronic kidney disease (CKD) patients have higher risk to develop cardiovascular disease (CVD) than non-CKD patients. Neutrophil lymphocyte ratio (NLR) in CKD patients reflects inflammation status and role as complementary prognostic marker to evaluate cardiovascular risk in stage 3 to 5 CKD. High prevalence of vitamin D deficiency commonly found in CKD patients, leads to endothelial dysfunction and increase inflammation. NGAL is used as renal injury biomarker but nowadays NGAL has been known plays important role in CVD pathophysiology. CVD identification in CKD patients is necessary to obtain CVD risk and to stratify mortality earlier in CKD patients. This study aimed to obtain the differences and continued to obtain cut off of NLR, vitamin D and NGAL in CKD patients undergoing hemodialysis (HD) with and without CVD if the differences was significantly. A cross-sectional study was conducted in dr. Cipto Mangunkusumo National Hospital Jakarta, in December- February 2020. Total subjects were 83, consists of two groups with and without the CVD. There were no significant differences of NLR and vitamin D in CKD patients undergoing hemodialysis (HD) with and without CVD. The significant difference was found only in NGAL with cut off 5.64 ng/ml. NLR was lower, meanwhile vitamin D and NGAL were higher in CKD patients undergoing HD with and without CVD.
Light Chain Multiple Myeloma: A Case of Distinctive Presentations Henrika, Fify; Wisdharilla, Reiva
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 31 No. 1 (2024)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v31i1.2088

Abstract

Multiple Myeloma (MM) is a malignancy of immunoglobulin-producing plasma cells. Lambda Light Chain Multiple Myeloma (LCMM) is a less common type of MM with a more aggressive course, which presents a diagnostic challenge due to the absence of typical M-spike on screening and unspecific manifestations. This case presented an initially misdiagnosed patient, who had an uncommon light chain pattern on electrophoresis, atypical plasmocytes in bone marrow smear, particular complications and risks associated with LCMM, and a worse prognosis.
Co-Authors Aida Lydia, Aida Ailinda Theodora Tedja, Ailinda Theodora Diana Aulia Indrasari, Nuri Dyah Kumalawati, July Putra, Gunawan Eka Riadi Wirawan Riadi Wirawan Sri Suryo Adiyanti Sukartini, Ninik Suzanna Immanuel Suzanna Immanuel T. Silangit Weny Rinawati Wisdharilla, Reiva YUSRA YUSRA