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All Journal International Journal of Public Health Science (IJPHS) Jurnal Teknologi Reaktor Nuklir Tri Dasa Mega
Nugraha, Eka Djatnika
Unknown Affiliation
Energy Health Professions Materials Science & Nanotechnology

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Maternal hair lead and cytokine pro-inflammatory effects in preterm birth Qolby, Qonita Nur; Dewantiningrum, Julian; Pramono, Besari Adi; Maharani, Nani; Nugraha, Eka Djatnika; Muniroh, Muflihatul
International Journal of Public Health Science (IJPHS) Vol 13, No 4: December 2024
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v13i4.24146

Abstract

This case-control study analyzed the lead (Pb), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-α) levels in pregnant women with preterm birth (PTB) in Central Java, Indonesia. Hair samples from 72 pregnant women were collected non-invasively. The prenatal exposure to Pb was determined with the total reflection X-ray fluorescence (TXRF) method. Serum IL-6 and TNF-α were examined using enzyme-linked immunosorbent assays (ELISA). The Pb concentration in hair was slightly higher in women with PTB than those without PTB; however, this difference was not statistically significant. An elevated hair Pb level was not associated with increased PTB risk (OR 24.69, 95% CI 0.93–653.82, p>0.05). A serum TNF-α level ≥27 pg/ml, a serum IL-6 level ≥9 pg/ml, and the spouse’s smoking frequency were significantly associated with increased PTB risk (TNF-α OR 42.25, 95% CI 5.26–339.61; IL-6 OR 22.33, 95% CI 3.12–158.54; spouse’s smoking frequency OR 1.28, 95% CI 1.09–1.5), while the maternal hemoglobin concentration significantly decreased PTB risk (OR 0.43, 95% CI 0.2–0.927). This study demonstrates that maternal hair Pb concentration has no significant relationship with PTB. Serum TNF-α, IL-6, and the spouse’s smoking frequency potentially increased PTB risk, while the maternal hemoglobin level is a protective factor.
Advancements in Accident Tolerance Fuel: A New Horizon in Nuclear Safety Ngarayana, I Wayan; Kurniawan, Rusbani; Rachman, Agus Nur; Nugraha, Eka Djatnika; Ekaranti, Egnes; Andani, Ika Wahyu
JURNAL TEKNOLOGI REAKTOR NUKLIR TRI DASA MEGA Vol 26, No 1 (2024): February 2024
Publisher : Pusat Teknologi Dan Keselamatan Reaktor Nuklir (PTKRN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/tdm.2024.7017

Abstract

Accident Tolerant Fuels (ATFs) represent a significant advancement in nuclear safety, offering the potential to mitigate the risks associated with nuclear reactor accidents. This paper provides a comprehensive overview of the development and current state of ATF technology, tracing its evolution and highlighting key technological milestones. Through an analysis of various case studies, we examine the practical application and performance of ATFs in real-world scenarios. Despite the promising capabilities of ATFs, their development and deployment are not without challenges. We delve into the technical, regulatory, and economic hurdles that must be overcome to realize the full potential of ATFs. Looking ahead, we explore the prospects of ATFs, discussing potential advancements and their implications for the nuclear industry. The findings of this paper underscore the transformative role of ATFs in enhancing nuclear reactor safety and charting a new horizon in nuclear technology.
HAZOP-Based Radiological Risk Assessment of Pebble Bed Fuel Handling Systems Kurniawan, Rusbani; Ekaranti, Egnes; Rachman, Agus Nur; Nugraha, Eka Djatnika; Ngarayana, I Wayan; Djunaidi, Zulkifli
JURNAL TEKNOLOGI REAKTOR NUKLIR TRI DASA MEGA Vol 26, No 1 (2024): February 2024
Publisher : Pusat Teknologi Dan Keselamatan Reaktor Nuklir (PTKRN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/tdm.2024.7016

Abstract

The High-Temperature Gas-Cooled Reactor (HTGR), a promising candidate for Generation IV nuclear reactors, boasts superior inherent passive safety features and a continuous fuel handling system. This system employs multi-pass cycles, utilizing pneumatic and gravitational mechanisms to feed, circulate, and unload the pebble bed fuel element. This paper presents a descriptive analysis assessing the safety risk of the fuel handling system design in HTR-10. The Hazard and Operability Study (HAZOP) methodology is employed to identify hazard parameters, deviation limitations, causes, impacts, and potential risks to the system’s main components. The establishment of probability scales, consequence criteria, risk level ratings, and control activities adheres to the ISO 31000 standard. Primary data were gathered through expert interviews, while secondary data were sourced from design layout documentation, literature reviews, and safety analysis reports. Six main components - the elevator, core, singulator, failed fuel separator, burnup measurement, and distributor - were selected as assessment nodes from the piping and instrumentation diagram. The assessment revealed that each node initially presented a moderate to extreme risk potential (risk level rating C to E). However, after applying the effectiveness index of the designed control, the residual risk for all nodes was reduced to an acceptable limit (risk rating A - very low). Therefore, the fuel handling system design already incorporates adequate control activities to mitigate potential safety risks due to system component failure. As safety risk assessment is dynamic, it should be reviewed periodically or whenever there are design changes at any project stage. This ensures the safety risk magnitude is consistently known and managed effectively.
Evaluation of Pixelated Plastic Scintillators Coupled to Multi-Channel Silicon Photomultipliers for Beta-Ray Detection and Source Localization Rachman, Agus Nur; Kurniawan, Rusbani; Ekaranti, Egnes; Wahyudi, Wahyudi; Nugraha, Eka Djatnika; Ngarayana, I Wayan; Hamdan, Moh
JURNAL TEKNOLOGI REAKTOR NUKLIR TRI DASA MEGA Vol 26, No 1 (2024): February 2024
Publisher : Pusat Teknologi Dan Keselamatan Reaktor Nuklir (PTKRN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/tdm.2024.7015

Abstract

This paper presents a novel detector design for radiation detection technology, based on pixelated plastic scintillators coupled to multi-channel silicon photomultipliers (SiPMs). This detector combines the efficiency of plastic scintillators with the sensitivity and versatility of SiPMs, Overcoming the limitations of traditional photomultiplier tubes in terms of durability, power consumption, and sensitivity. The compact and modular nature of the detector makes it suitable for diverse environments and applications, such as portable radiation monitoring devices or integration into existing experimental setups. The performance of the detector was evaluated using beta-ray sources of 36Cl and 90Sr, and it was demonstrated that the detector can detect and localize the point source with high accuracy and resolution.
Co-Authors Agus Nur Rachman, Agus Nur Andani, Ika Wahyu Besari Adi Pramono Ekaranti, Egnes Hamdan, Moh Julian Dewantiningrum Kurniawan, Rusbani Muniroh, Muflihatul Nani Maharani Ngarayana, I Wayan Qolby, Qonita Nur Wahyudi Wahyudi Zulkifli Djunaidi, Zulkifli