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Albumin Telur Sebagai Lem pada Operasi Cangkok Konjungtiva Kartiwa, R. Angga; Enus, Sutarya; Boediono, Arief; Miraprahesti, Retti N.
Majalah Kedokteran Bandung Vol 48, No 4 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v48n4.925

Abstract

Cangkok konjungtiva sudah lama digunakan pada bidang oftalmologi. Metode yang digunakan saat ini untuk menempelkan cangkok konjungtiva adalah menggunakan teknik jahitan dan lem fibrin. Pada penelitian ini dilakukan uji coba menggunakan lem albumin pada cangkok konjungtiva kelinci sebagai alternatif lain selain menggunakan teknik jahitan dalam penempelan cangkok konjungtiva. Tujuan penelitian adalah membandingkan penyembuhan luka cangkok konjungtiva bulbi antara teknik lem albumin dan jahitan pada mata kelinci. Dilakukan animalexperimental study pada 32 mata (16 ekor kelinci) di PT. Bio Farma (Persero) dan laboratorium Histologi, Fakultas Kedokteran Universitas Padjadjaran dari bulan Maret 2014–Juli 2014, terbagi kelompok teknik lem albumin dan teknik jahitan. Dilakukan pemeriksaan meliputi perbandingan derajat perlekatan cangkok konjungtiva bulbi pada teknik lem albumin dan teknik jahitan yang diamati hari-1 pascabedah serta dilakukan pemeriksaan histologis secara mikroskopik untuk mendapatkan data celah luka yang diamati 10 menit dan hari-7 pascabedah. Analisis data dilakukan dengan Mann-Whitney test for small sample. Hasil penelitian memperlihatkan perlekatan cangkok konjungtiva bulbi secara bermakna lebih kuat pada teknik lem albumin (derajat 4) dibanding dengan teknik jahitan (derajat 2 dan 3) pada hari-1 pascabedah dengan nilai p=0,000 serta terdapat perbedaan celah luka (wound gap) bermakna antara teknik lem albumin (0–0,33 µm) dan jahitan (5,33–14 µm) (p=0,0005)pada cangkok konjungtiva dilihat sepuluh menit pascabedah dan pada hari-7 pascabedah untuk teknik lem albumin (0 µm) dan teknik jahitan (0,33–4 µm) dengan nilai p=0,0005. Simpulan penelitian ini adalah derajat perlekatan jaringan cangkok pada teknik lem albumin lebih baik dibanding dengan jahitan hari-1 pascabedah, sedangkan celah luka lebih kecil pada teknik lem albumin dibanding dengan teknik jahitan pada pengamatan 10 menit dan hari-7 pascabedah. [MKB. 2016;48(4):241–8]Kata kunci: Jahitan, lem albumin, penyembuhan luka konjungtivaEgg Albumin as Adhesive in Conjunctival Graft SurgeryCConjunctival graft has been frequently used in the field of ophthalmology. The frequently used methods to attach a conjunctival graft are suture technique and the use of fibrin glue. This study was to investigate albumin glue as an alternative to suture technique in attaching conjunctival grafts in rabbits. The aim of this study was to compare the conjunctival wound healing between albumin glue and suture technique in rabbit eye as a model. This was an experimental animal study that included 32 eyes (16 rabbits) conducted at PT. Bio Farma (Persero) and the Histology Laboratory, Faculty of Medicine, Universitas Padjadjaran from March 2014 to July 2104. The subjects in this study were divided into albumin glue group and suture technique group. The examinations were comparison of conjunctival graft attachment and histologic microscopic examination to assess the wound gap. Data analysis was performed statistically using Mann-Whitney test for small sample. The statistical analysis results showed that the graft attachment was significantly better when using albumin glue (grade 4) compared to suture (grade 2–3) on day-1 after surgery (p=0.000). The wound gap was smaller using albumin glue (0-0,33 µm versus 5,33-14 µm; p0.0005) 10 minutes after surgery and 0 µm versus 0.33–4 µm, p 0,0005, on day-7 after surgery. In conclusion, graft attachment using albumi n glue is better and the wound gap is smaller when using albumin glue compared to the suture technique. [MKB. 2016;48(4):241–8]Key words: Albumin glue, conjunctival wound healing, suture
KEBERHASILAN OPERASI TRABEKULEKTOMI PADA GLAUKOMA SUDUT TERBUKA PRIMER PERIODE 2019-2021 Radilia, Fasya; Rifada, R. Maula; Kartiwa, R. Angga
Oftalmologi : Jurnal Kesehatan Mata Indonesia Vol 5 No 2 (2023): Jurnal Oftalmologi Vol 5 No 2 2023
Publisher : Pusat Mata Nasional Rumah Sakit Mata Cicendo Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/ojkmi.v5i2.50

Abstract

Introduction: Glaucoma represents a group of diseases defined by a characteristic optic neuropathy that is consistent with remodeling of the connective tissue elements of the optic nerve head and with loss of neural tissue associated with the eventual development of distinctive patterns of visual dysfunction. The most common surgery for glaucoma treatment is trabeculectomy, which in principle is done by creating a new channel that drains the aqueous humor, and return the intraocular pressure to normal levels. Objective: This study aimed to know the success rate of trabeculectomy in primary open-angle glaucoma. Methods: This study used a retrospective descriptive research method and was conducted in the Medical Records Center of the Cicendo National Eye Hospital, Bandung City with a data collection period of 21 July 2022 – 6 September 2022. The data collection process was carried out by looking at secondary data from medical records of patients with primary open-angle glaucoma for the period January 2019 – December 2021. Results: Mean IOP decreased from 32.6±12.9 before surgery, to 19.8±10 one week after surgery, and 18.8±7.3 one month after surgery. The overall success rate reaches 82.1%. Conclusions: The success rate for open-angle glaucoma treated with trabeculectomy at Cicendo National Eye hospital is considered good with a total success rate of 82.1% with or without anti-glaucoma medication to control IOP after surgery.
Relationship of Peripapillary Retinal Perfusion with Peripapillary Retinal Nerve Fiber Layer Thickness in Diabetes Mellitus Patients without Diabetic Retinopathy Dwijayanti, Sindi; Irfani, Irawati; Sirait, Susanti Natalya; Gustianty, Elsa; Iskandar, Erwin; Kartiwa, R. Angga
International Journal of Retina Vol 4 No 2 (2021): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2021.vol004.iss002.161

Abstract

Introduction: Impaired blood flow is an early sign of retinal dysfunction in diabetes. Impaired blood flow of the radial peripapillary capillaries can affect the Retinal Nerve Fiber Layer (RNFL) or ganglion cell function. Methods: This was an analytic cross-sectional study in February-April 2019 at Bandung. The subjects of this study were 41 people (79 eyes) divided into two groups, group A (healthy subjects) 19 people (37 eyes) and group B (DM type 2 without diabetic retinopathy) 22 people (42 eyes). Peripapillary retinal perfusion was assesed using OCT Angiography and RNFL thickness was assesed using OCT. Pearson or Spearman correlation statistics test was used to analyze the result. P value ≤0.05 was consiedered significant. Results: There was a decrease in peripapillary retinal perfusion density in the inferior quadrant (P = 0.003) and flux index throughout the peripapillary retinal quadrant (P = 0.0001) but an increase in RNFL thickness in the peripapillary temporal quadrant (P = 0.012) compared to control grup. Positive correlation was found between peripapillary retinal perfusion density and RNFL thickness globally (r = 0.480, P = 0.001), superior quadrant (r = 0.436, P = 0.004), and inferior quadrant (r = 0.608, P = 0.000). A positive correlation was also found between the peripapillary flux and RNFL thickness globally (r = 0.517, P = 0.000), superior quadrant (r = 0.630, P = 0.000), and inferior quadrant (r = 0.519, P = 0.000). Conclusions: There was a relationship between peripapillary retinal perfusion and RNFL thickness in DM patients without diabetic retinopathy. Keywords: Peripapillary perfusion, RNFL thickness, Diabetes.