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All Journal Majalah Kesehatan FKUB Asian Journal of Health Research Indonesian Journal of Cancer Jurnal Ilmiah Ilmu Terapan Universitas Jambi
Irma Darinafitri
Radiology Department, Universitas Brawijaya/ Saiful Anwar Hospital, Malang, Indonesia
Biochemistry, Genetics & Molecular Biology Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health

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Tinjauan Literatur : DIFERENSIASI TUMOR PRIMER TULANG BELAKANG SECARA RADIOLOGIS Aurora, Habiba; Darinafitri, Irma
Majalah Kesehatan FKUB Vol 6, No 3 (2019): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (876.936 KB) | DOI: 10.21776/ub.majalahkesehatan.2019.006.03.7

Abstract

Tumor pada tulang belakang yang terbanyak adalah metastasis, namun tumor primer pada tulang belakang lebih jarang didapatkan. Kesulitan dalam menegakkan diagnosis tumor primer pada tulang belakang karena pada tumor primer memiliki beberapa diagnosis banding serta struktur yang kompleks dari tulang belakang. Ketepatan diagnosis sangat penting untuk menentukan terapi dan mempengaruhi prognosis pasien. Karakteristik tumor secara radiologi sangat membantu dalam mengarahkan diagnosis. Evaluasi secara radiologis didasarkan pada lokasi, matriks tumor, dan usia pasien  Pemeriksaan radiologis meliputi radiografi , CT scan, MRI, angiografi, sidik tulang (bone scintigraphy) serta single photon emission computed tomography (SPECT) dan positron emission tomography (PET). Masing-masing modalitas memiliki kelebihan dan kekurangan dalam pemeriksaan. Karenanya penting untuk mengetahui karakteristik dari tumor pada tulang belakang dan pilihan pemeriksaan radiologis yang tepat untuk diagnosis tumor pada tulang belakang. 
A Case Report of Radiation Therapy as Definitive Treatment for Desmoid Tumor in a Young Girl Rafiq Sulistyo Nugroho; Irma Darinafitri; Eviana Norahmawati; Istan Irmansyah Irsan; Satria Pandu Persada Isma
Indonesian Journal of Cancer Vol 17, No 3 (2023): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v17i3.977

Abstract

Introduction: Desmoid tumor is a benign growth that can exhibit aggressiveness and various patterns, resulting in a wide range of management methods. These methods include observation to active interventions, such as surgery, radiation, and systemic therapy. Therefore, this case report aimed to present the role of radiation therapy for desmoid tumors in a young girl who refused limb amputation to preserve the organ.Case Presentation: This study presented the case of a 13-year-old girl with a vast and painful desmoid tumor in the left upper arm. Magnetic resonance imaging (MRI) on the left shoulder showed an 8 x 9 x 17 cm solid soft tissue mass on the left deltoid muscle with the necrotic component that expands to adjacent cutaneous and subcutaneous tissue. In this case, the left humerus attaches to the deep brachial artery and vein. Previous pathological studies with immunohistochemicals showed desmoid fibromatosis. A multidisciplinary team discussion led to the selection of, radiotherapy for treatment because of tumor localization and proximity to the critical structure. Radiation was also selected as the definitive therapy of choice with the aim of local control and organ preservation. Furthermore, the radiation dose was 56 Gy in 2 Gy per fraction over six weeks. After six months of follow-up, the patient reported pain relief, improved range of motion, and reduced tumor size.Conclusion: Radiotherapy reduced desmoid tumor size and improved symptoms without compromising organ function in young girls.
THE RELATIONSHIP BETWEEN SPINOPELVIC PARAMETERS ON RADIOGRAPHY AND THE DEGREE OF LUMBOSACRAL INTERVERTEBRAL DISC HERNIATION ON MRI Nasrizarni, Nasrizarni; Darinafitri, Irma; Azmy, Abdullah
Jurnal Ilmiah Ilmu Terapan Universitas Jambi Vol. 9 No. 4 (2025): Volume 9, Nomor 4, December 2025
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jiituj.v9i4.50238

Abstract

Given the limited availability of lumbosacral MRI, currently the most accurate modality for assessing the severity of intervertebral disc herniation, in many hospitals in Indonesia, evaluation of spinopelvic parameters on lumbosacral radiographs is expected to serve as an alternative predictor of lumbar disc herniation grade. This study aims to analyze the relationship between spinopelvic parameters and the degree of lumbosacral intervertebral disc herniation, and to identify which parameters are most accurate in predicting the degree of the herniation in patients with low back pain. This research is a retrospective analytic observational study with a cross-sectional design that included 52 patients with low back pain who underwent lumbosacral radiography and MRI at Saiful Anwar General Hospital in 2022–2023. The degree of disc herniation was assessed on sagittal and axial lumbosacral MRI. In contrast, spinopelvic parameters, including pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), lumbar lordosis (LL), lumbosacral angle (LSA), sacral table angle (STA), and sacral kyphosis (SK), were measured on lumbosacral radiographs. Statistical tests were conducted on four groups (normal, bulging, protrusion, and extrusion). Using Spearman’s test, a correlation was found between lumbar lordosis angle and the degree of lumbosacral intervertebral disc herniation, with p=0.011 (p<0.05). One-way ANOVA showed a significant difference in lumbar lordosis across herniation grades, with p=0.028 (p<0.05). A smaller lumbar lordosis angle was associated with a higher risk of lumbosacral intervertebral disc herniation. Therefore, lumbar lordosis, as one of the spinopelvic parameters, may be considered a predictive factor for lumbosacral disc herniation.
Radiographic Differentiation of Tibiofemoral Joint Space Width in Kellgren–Lawrence Grade 2 and 3 Osteoarthritis in Malang Irma Darinafitri; Suaydiy Okdiyanzah
Asian Journal of Health Research Vol. 5 No. 1 (2026): Volume 5 No 1 (April) 2026
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v5i1.329

Abstract

Introduction: Osteoarthritis (OA) is a leading cause of disability worldwide. Although the Kellgren–Lawrence (KL) grading system is widely used, it remains subjective. Quantitative fixed joint space width (fJSW) offers a more objective assessment of structural severity, and is particularly relevant in populations such as Javanese communities, where habitual squatting may influence knee joint loading patterns, making evaluation in Malang, East Java, of specific interest. Material and Methods: This study analyzed 111 knees (KL grade 2 or 3) at Saiful Anwar Hospital in 2024. Medial and lateral fJSW were measured on standardized weight-bearing radiographs using a perpendicular subchondral technique. Results: The participants were predominantly female (69.86%) and aged 40-60 years (47.95 %). KL grade 2 was more frequent than grade 3 (56.76% vs. 43.24%), with more bilateral involvement observed (52.05%). Mean medial fJSW are 3.55 ± 1.72 mm in KL 2 and 3.12 ± 1.89 mm in KL 3, while mean lateral fJSW are  4.47 ± 1.26 mm in KL 2 and 5.15 ± 2.27 mm in KL 3. An optimal medial cutoff of 5.03 mm demonstrated high sensitivity (93.8%) but low specificity (25.4%) for disease staging. Despite limited specificity, this threshold may be useful as a screening tool to reduce underdiagnosis of KL grade 3 osteoarthritis by prioritizing sensitivity in detecting more advanced disease. Conclusion: Findings confirm a pattern of medial narrowing and lateral preservation characteristic of varus-driven attrition. However, the low specificity of fJSW suggests that quantitative narrowing alone is insufficient for grading; it must be integrated with other structural domains, such as osteophyte formation, to differentiate KL2 from KL3.
Co-Authors Abdullah Azmy Eviana Norahmawati Habiba Aurora Istan Irmansyah Irsan Nasrizarni, Nasrizarni Rafiq Sulistyo Nugroho Satria Pandu Persada Isma Suaydiy Okdiyanzah